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Michele Pagano

Michele Pagano, MD

Chair, Department of Biochemistry and Molecular Pharmacology

May Ellen and Gerald Jay Ritter Professor of Oncology, Department of Biochemistry and Molecular Pharmacology

Keywords
cell cycle control and ubiquitin-mediated degradation, cancer, genome integrity
Summary

Our laboratory explores the roles that the ubiquitin system plays in fundamental cellular processes, such as cell growth, proliferation, and the DNA damage response. Our group is also committed to understanding how the deregulation of this regulatory network contributes to malignant transformation. 

Phone

212-263-5322

Fax

212-263-5107

Academic office

The Alexandria Center of Life, 450 East 29th Street

East Tower, 802

New York, NY 10016

Lab Website
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Chair, Department of Biochemistry and Molecular Pharmacology

MD from University of Naples Federico II

Deng, Jiehui; Thennavan, Aatish; Dolgalev, Igor; Chen, Ting; Li, Jie; Marzio, Antonio; Poirier, John T; Peng, David; Bulatovic, Mirna; Mukhopadhyay, Subhadip; Silver, Heather; Papadopoulos, Eleni; Pyon, Val; Thakurdin, Cassandra; Han, Han; Li, Fei; Li, Shuai; Ding, Hailin; Hu, Hai; Pan, Yuanwang; Weerasekara, Vajira; Jiang, Baishan; Wang, Eric S; Ahearn, Ian; Philips, Mark; Papagiannakopoulos, Thales; Tsirigos, Aristotelis; Rothenberg, Eli; Gainor, Justin; Freeman, Gordon J; Rudin, Charles M; Gray, Nathanael S; Hammerman, Peter S; Pagano, Michele; Heymach, John V; Perou, Charles M; Bardeesy, Nabeel; Wong, Kwok-Kin

Nature cancer. 2021 May; 2(5):503-514

Mena, Elijah L; Donahue, Callie J; Vaites, Laura Pontano; Li, Jie; Rona, Gergely; O'Leary, Colin; Lignitto, Luca; Miwatani-Minter, Bearach; Paulo, Joao A; Dhabaria, Avantika; Ueberheide, Beatrix; Gygi, Steven P; Pagano, Michele; Harper, J Wade; Davey, Robert A; Elledge, Stephen J

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2021 04 27; 118(17):

Maiani, Emiliano; Milletti, Giacomo; Nazio, Francesca; Holdgaard, Søs Grønbæk; Bartkova, Jirina; Rizza, Salvatore; Cianfanelli, Valentina; Lorente, Mar; Simoneschi, Daniele; Di Marco, Miriam; D'Acunzo, Pasquale; Di Leo, Luca; Rasmussen, Rikke; Montagna, Costanza; Raciti, Marilena; De Stefanis, Cristiano; Gabicagogeascoa, Estibaliz; Rona, Gergely; Salvador, Nélida; Pupo, Emanuela; Merchut-Maya, Joanna Maria; Daniel, Colin J; Carinci, Marianna; Cesarini, Valeriana; O'sullivan, Alfie; Jeong, Yeon-Tae; Bordi, Matteo; Russo, Francesco; Campello, Silvia; Gallo, Angela; Filomeni, Giuseppe; Lanzetti, Letizia; Sears, Rosalie C; Hamerlik, Petra; Bartolazzi, Armando; Hynds, Robert E; Pearce, David R; Swanton, Charles; Pagano, Michele; Velasco, Guillermo; Papaleo, Elena; De Zio, Daniela; Maya-Mendoza, Apolinar; Locatelli, Franco; Bartek, Jiri; Cecconi, Francesco

Nature. 2021 Apr; 592(7856):799-803

Simoneschi, Daniele; Rona, Gergely; Zhou, Nan; Jeong, Yeon-Tae; Jiang, Shaowen; Milletti, Giacomo; Arbini, Arnaldo A; O'Sullivan, Alfie; Wang, Andrew A; Nithikasem, Sorasicha; Keegan, Sarah; Siu, Yik; Cianfanelli, Valentina; Maiani, Emiliano; Nazio, Francesca; Cecconi, Francesco; Boccalatte, Francesco; Fenyö, David; Jones, Drew R; Busino, Luca; Pagano, Michele

Nature. 2021 Apr; 592(7856):789-793

Lignitto, Luca; Pagano, Michele

Developmental cell. 2021 Mar 08; 56(5):569-570

Salamina, Marco; Montefiore, Bailey C; Liu, Mengxi; Wood, Daniel J; Heath, Richard; Ault, James R; Wang, Lan-Zhen; Korolchuk, Svitlana; Baslé, Arnaud; Pastok, Martyna W; Reeks, Judith; Tatum, Natalie J; Sobott, Frank; Arold, Stefan T; Pagano, Michele; Noble, Martin E M; Endicott, Jane A

Journal of molecular biology. 2021 Mar 05; 433(5):166795

Moro, Loredana; Pagano, Michele

Molecular & cellular oncology. 2020 Oct 22; 7(6):1833698

Pálinkás, Hajnalka L; Békési, Angéla; Róna, Gergely; Pongor, Lőrinc; Papp, Gábor; Tihanyi, Gergely; Holub, Eszter; Póti, Ádám; Gemma, Carolina; Ali, Simak; Morten, Michael J; Rothenberg, Eli; Pagano, Michele; Szűts, Dávid; Győrffy, Balázs; Vértessy, Beáta G

eLife. 2020 09 21; 9: