Skip to Main Content
Michele Pagano

Michele Pagano, MD

Chair, Department of Biochemistry and Molecular Pharmacology

May Ellen and Gerald Jay Ritter Professor of Oncology, Department of Biochemistry and Molecular Pharmacology

cell cycle control and ubiquitin-mediated degradation, cancer, genome integrity

Our laboratory explores the roles that the ubiquitin system plays in fundamental cellular processes, such as cell growth, proliferation, and the DNA damage response. Our group is also committed to understanding how the deregulation of this regulatory network contributes to malignant transformation. 





Academic office

522 First Avenue, Smilow Research Bldg.

11, 1107

New York, NY 10016

Lab Website
Is this your profile?

Chair, Department of Biochemistry and Molecular Pharmacology

MD from University of Naples Federico II

Horváth, András; Rona, Gergely; Pagano, Michele; Jordan, Philip W

BMC molecular & cell biology. 2020 May 08; 21(1):36

Wang, Hui; Shi, Hui; Rajan, Malini; Canarie, Elizabeth R; Hong, Seoyeon; Simoneschi, Daniele; Pagano, Michele; Bush, Matthew F; Stoll, Stefan; Leibold, Elizabeth A; Zheng, Ning

Molecular cell. 2020 Apr 02; 78(1):31-41.e5

Reynders, Martin; Matsuura, Bryan S; Bérouti, Marleen; Simoneschi, Daniele; Marzio, Antonio; Pagano, Michele; Trauner, Dirk

Science advances. 2020 02; 6(8):eaay5064

Rona, Gergely; Pagano, Michele

Genes & development. 2019 Dec 01; 33(23-24):1615-1616

Lignitto, Luca; LeBoeuf, Sarah E; Homer, Harrison; Jiang, Shaowen; Askenazi, Manor; Karakousi, Triantafyllia R; Pass, Harvey I; Bhutkar, Arjun J; Tsirigos, Aristotelis; Ueberheide, Beatrix; Sayin, Volkan I; Papagiannakopoulos, Thales; Pagano, Michele

Cell. 2019 Jul 11; 178(2):316-329.e18

Kuchay, Shafi; Wang, Hui; Marzio, Antonio; Jain, Kunj; Homer, Harrison; Fehrenbacher, Nicole; Philips, Mark R; Zheng, Ning; Pagano, Michele

Nature structural & molecular biology. 2019 Jul; 26(7):628-636

Clijsters, Linda; Hoencamp, Claire; Calis, Jorg J A; Marzio, Antonio; Handgraaf, Shanna M; Cuitino, Maria C; Rosenberg, Brad R; Leone, Gustavo; Pagano, Michele

Molecular cell. 2019 Jun 20; 74(6):1264-1277.e7

Cuitiño, Maria C; Pécot, Thierry; Sun, Daokun; Kladney, Raleigh; Okano-Uchida, Takayuki; Shinde, Neelam; Saeed, Resham; Perez-Castro, Antonio J; Webb, Amy; Liu, Tom; Bae, Soo In; Clijsters, Linda; Selner, Nicholas; Coppola, Vincenzo; Timmers, Cynthia; Ostrowski, Michael C; Pagano, Michele; Leone, Gustavo

Cell reports. 2019 Jun 18; 27(12):3547-3560.e5