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Michele Pagano

Michele Pagano, MD

Chair, Department of Biochemistry and Molecular Pharmacology

May Ellen and Gerald Jay Ritter Professor of Oncology, Department of Biochemistry and Molecular Pharmacology

Keywords
cell cycle control and ubiquitin-mediated degradation, cancer, genome integrity
Summary

Our laboratory explores the roles that the ubiquitin system plays in fundamental cellular processes, such as cell growth, proliferation, and the DNA damage response. Our group is also committed to understanding how the deregulation of this regulatory network contributes to malignant transformation. 

Phone

212-263-5322

Fax

212-263-5107

Academic office

The Alexandria Center of Life, 450 East 29th Street

East Tower, 802

New York, NY 10016

Lab Website
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Chair, Department of Biochemistry and Molecular Pharmacology

MD from University of Naples Federico II

Rona, Gergely; Zeke, Andras; Miwatani-Minter, Bearach; de Vries, Maren; Kaur, Ramanjit; Schinlever, Austin; Garcia, Sheena Faye; Goldberg, Hailey V; Wang, Hui; Hinds, Thomas R; Bailly, Fabrice; Zheng, Ning; Cotelle, Philippe; Desmaële, Didier; Landau, Nathaniel R; Dittmann, Meike; Pagano, Michele

Cell death & differentiation. 2022 Feb; 29(2):285-292

Marzio, Antonio; Kurz, Emma; Sahni, Jennifer M; Di Feo, Giuseppe; Puccini, Joseph; Jiang, Shaowen; Hirsch, Carolina Alcantara; Arbini, Arnaldo A; Wu, Warren L; Pass, Harvey I; Bar-Sagi, Dafna; Papagiannakopoulos, Thales; Pagano, Michele

Cell. 2022 Jan 06; 185(1):169-183.e19

Chaikovsky, Andrea C; Sage, Julien; Pagano, Michele; Simoneschi, Daniele

DNA & cell biology. 2021 Dec; 40(12):1457-1461

Duan, Shanshan; Moro, Loredana; Qu, Rui; Simoneschi, Daniele; Cho, Hyunwoo; Jiang, Shaowen; Zhao, Huiyong; Chang, Qing; de Stanchina, Elisa; Arbini, Arnaldo A; Pagano, Michele

Cell reports. 2021 Oct 19; 37(3):109870

Duan, Shanshan; Pagano, Michele

Cell chemical biology. 2021 Jul 15; 28(7):918-933

Deng, Jiehui; Thennavan, Aatish; Dolgalev, Igor; Chen, Ting; Li, Jie; Marzio, Antonio; Poirier, John T; Peng, David; Bulatovic, Mirna; Mukhopadhyay, Subhadip; Silver, Heather; Papadopoulos, Eleni; Pyon, Val; Thakurdin, Cassandra; Han, Han; Li, Fei; Li, Shuai; Ding, Hailin; Hu, Hai; Pan, Yuanwang; Weerasekara, Vajira; Jiang, Baishan; Wang, Eric S; Ahearn, Ian; Philips, Mark; Papagiannakopoulos, Thales; Tsirigos, Aristotelis; Rothenberg, Eli; Gainor, Justin; Freeman, Gordon J; Rudin, Charles M; Gray, Nathanael S; Hammerman, Peter S; Pagano, Michele; Heymach, John V; Perou, Charles M; Bardeesy, Nabeel; Wong, Kwok-Kin

Nature cancer. 2021 May; 2(5):503-514

Mena, Elijah L; Donahue, Callie J; Vaites, Laura Pontano; Li, Jie; Rona, Gergely; O'Leary, Colin; Lignitto, Luca; Miwatani-Minter, Bearach; Paulo, Joao A; Dhabaria, Avantika; Ueberheide, Beatrix; Gygi, Steven P; Pagano, Michele; Harper, J Wade; Davey, Robert A; Elledge, Stephen J

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2021 04 27; 118(17):

Maiani, Emiliano; Milletti, Giacomo; Nazio, Francesca; Holdgaard, Søs Grønbæk; Bartkova, Jirina; Rizza, Salvatore; Cianfanelli, Valentina; Lorente, Mar; Simoneschi, Daniele; Di Marco, Miriam; D'Acunzo, Pasquale; Di Leo, Luca; Rasmussen, Rikke; Montagna, Costanza; Raciti, Marilena; De Stefanis, Cristiano; Gabicagogeascoa, Estibaliz; Rona, Gergely; Salvador, Nélida; Pupo, Emanuela; Merchut-Maya, Joanna Maria; Daniel, Colin J; Carinci, Marianna; Cesarini, Valeriana; O'sullivan, Alfie; Jeong, Yeon-Tae; Bordi, Matteo; Russo, Francesco; Campello, Silvia; Gallo, Angela; Filomeni, Giuseppe; Lanzetti, Letizia; Sears, Rosalie C; Hamerlik, Petra; Bartolazzi, Armando; Hynds, Robert E; Pearce, David R; Swanton, Charles; Pagano, Michele; Velasco, Guillermo; Papaleo, Elena; De Zio, Daniela; Maya-Mendoza, Apolinar; Locatelli, Franco; Bartek, Jiri; Cecconi, Francesco

Nature. 2021 Apr; 592(7856):799-803