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Michele Pagano

Michele Pagano, MD

Chair, Department of Biochemistry and Molecular Pharmacology

May Ellen and Gerald Jay Ritter Professor of Oncology, Department of Biochemistry and Molecular Pharmacology

Keywords
cell cycle control and ubiquitin-mediated degradation, cancer, genome integrity
Summary

Our laboratory explores the roles that the ubiquitin system plays in fundamental cellular processes, such as cell growth, proliferation, and the DNA damage response. Our group is also committed to understanding how the deregulation of this regulatory network contributes to malignant transformation. 

Phone

212-263-5322

Fax

212-263-5107

Academic office

522 First Avenue, Smilow Research Bldg.

11, 1107

New York, NY 10016

Lab Website
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May Ellen and Gerald Jay Ritter Professor of Oncology, Department of Biochemistry and Molecular Pharmacology

Chair, Department of Biochemistry and Molecular Pharmacology

MD from University of Naples Federico II

Marzio, Antonio; Puccini, Joseph; Kwon, Youngho; Maverakis, Natalia K; Arbini, Arnaldo; Sung, Patrick; Bar-Sagi, Dafna; Pagano, Michele

Molecular cell. 2019 Jan 17; 73(2):224-237.e6

Jeong, Yeon-Tae; Simoneschi, Daniele; Keegan, Sarah; Melville, David; Adler, Natalia S; Saraf, Anita; Florens, Laurence; Washburn, Michael P; Cavasotto, Claudio N; Fenyö, David; Cuervo, Ana Maria; Rossi, Mario; Pagano, Michele

eLife. 2018 12 31; 7:

Kuchay, Shafi; Saeed, Mohsan; Giorgi, Carlotta; Li, Jie; Hoffmann, Hans-Heinrich; Pinton, Paolo; Rice, Charles M; Pagano, Michele

Cell reports. 2018 Oct 23; 25(4):833-840.e3

Mavrommati, Ioanna; Faedda, Roberta; Galasso, Giovanni; Li, Jie; Burdova, Kamila; Fischer, Roman; Kessler, Benedikt M; Carrero, Zunamys I; Guardavaccaro, Daniele; Pagano, Michele; D'Angiolella, Vincenzo

Cell reports. 2018 Sep 25; 24(13):3404-3412

Rona, Gergely; Roberti, Domenico; Yin, Yandong; Pagan, Julia K; Homer, Harrison; Sassani, Elizabeth; Zeke, Andras; Busino, Luca; Rothenberg, Eli; Pagano, Michele

eLife. 2018 07 09; 7:

Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A; Abrams, John M; Adam, Dieter; Agostinis, Patrizia; Alnemri, Emad S; Altucci, Lucia; Amelio, Ivano; Andrews, David W; Annicchiarico-Petruzzelli, Margherita; Antonov, Alexey V; Arama, Eli; Baehrecke, Eric H; Barlev, Nickolai A; Bazan, Nicolas G; Bernassola, Francesca; Bertrand, Mathieu J M; Bianchi, Katiuscia; Blagosklonny, Mikhail V; Blomgren, Klas; Borner, Christoph; Boya, Patricia; Brenner, Catherine; Campanella, Michelangelo; Candi, Eleonora; Carmona-Gutierrez, Didac; Cecconi, Francesco; Chan, Francis K-M; Chandel, Navdeep S; Cheng, Emily H; Chipuk, Jerry E; Cidlowski, John A; Ciechanover, Aaron; Cohen, Gerald M; Conrad, Marcus; Cubillos-Ruiz, Juan R; Czabotar, Peter E; D'Angiolella, Vincenzo; Dawson, Ted M; Dawson, Valina L; De Laurenzi, Vincenzo; De Maria, Ruggero; Debatin, Klaus-Michael; DeBerardinis, Ralph J; Deshmukh, Mohanish; Di Daniele, Nicola; Di Virgilio, Francesco; Dixit, Vishva M; Dixon, Scott J; Duckett, Colin S; Dynlacht, Brian D; El-Deiry, Wafik S; Elrod, John W; Fimia, Gian Maria; Fulda, Simone; García-Sáez, Ana J; Garg, Abhishek D; Garrido, Carmen; Gavathiotis, Evripidis; Golstein, Pierre; Gottlieb, Eyal; Green, Douglas R; Greene, Lloyd A; Gronemeyer, Hinrich; Gross, Atan; Hajnoczky, Gyorgy; Hardwick, J Marie; Harris, Isaac S; Hengartner, Michael O; Hetz, Claudio; Ichijo, Hidenori; Jäättelä, Marja; Joseph, Bertrand; Jost, Philipp J; Juin, Philippe P; Kaiser, William J; Karin, Michael; Kaufmann, Thomas; Kepp, Oliver; Kimchi, Adi; Kitsis, Richard N; Klionsky, Daniel J; Knight, Richard A; Kumar, Sharad; Lee, Sam W; Lemasters, John J; Levine, Beth; Linkermann, Andreas; Lipton, Stuart A; Lockshin, Richard A; López-Otín, Carlos; Lowe, Scott W; Luedde, Tom; Lugli, Enrico; MacFarlane, Marion; Madeo, Frank; Malewicz, Michal; Malorni, Walter; Manic, Gwenola; Marine, Jean-Christophe; Martin, Seamus J; Martinou, Jean-Claude; Medema, Jan Paul; Mehlen, Patrick; Meier, Pascal; Melino, Sonia; Miao, Edward A; Molkentin, Jeffery D; Moll, Ute M; Muñoz-Pinedo, Cristina; Nagata, Shigekazu; Nuñez, Gabriel; Oberst, Andrew; Oren, Moshe; Overholtzer, Michael; Pagano, Michele; Panaretakis, Theocharis; Pasparakis, Manolis; Penninger, Josef M; Pereira, David M; Pervaiz, Shazib; Peter, Marcus E; Piacentini, Mauro; Pinton, Paolo; Prehn, Jochen H M; Puthalakath, Hamsa; Rabinovich, Gabriel A; Rehm, Markus; Rizzuto, Rosario; Rodrigues, Cecilia M P; Rubinsztein, David C; Rudel, Thomas; Ryan, Kevin M; Sayan, Emre; Scorrano, Luca; Shao, Feng; Shi, Yufang; Silke, John; Simon, Hans-Uwe; Sistigu, Antonella; Stockwell, Brent R; Strasser, Andreas; Szabadkai, Gyorgy; Tait, Stephen W G; Tang, Daolin; Tavernarakis, Nektarios; Thorburn, Andrew; Tsujimoto, Yoshihide; Turk, Boris; Vanden Berghe, Tom; Vandenabeele, Peter; Vander Heiden, Matthew G; Villunger, Andreas; Virgin, Herbert W; Vousden, Karen H; Vucic, Domagoj; Wagner, Erwin F; Walczak, Henning; Wallach, David; Wang, Ying; Wells, James A; Wood, Will; Yuan, Junying; Zakeri, Zahra; Zhivotovsky, Boris; Zitvogel, Laurence; Melino, Gerry; Kroemer, Guido

Cell death & differentiation. 2018 Mar; 25(3):486-541

D'Alessandro, Matthew; Beesley, Stephen; Kim, Jae Kyoung; Jones, Zachary; Chen, Rongmin; Wi, Julie; Kyle, Kathleen; Vera, Daniel; Pagano, Michele; Nowakowski, Richard; Lee, Choogon

Current biology. CB. 2017 Nov 20; 27(22):3454-3467.e8

Fehrenbacher, Nicole; Tojal da Silva, Israel; Ramirez, Craig; Zhou, Yong; Cho, Kwang-Jin; Kuchay, Shafi; Shi, Jie; Thomas, Susan; Pagano, Michele; Hancock, John F; Bar-Sagi, Dafna; Philips, Mark R

Journal of cell biology. 2017 08 07; 216(8):2329-2338