Niels Ringstad

Niels Ringstad, PhD

Professor, Department of Cell Biology

Keywords
channels and transporters, developmental genetics, genome integrity, metabolism, molecular, cellular, & translational neuroscience, neuromodulation, behavioral genetics
Summary

We seek to understand molecular mechanisms that govern the development and function of neuromodulatory systems in the brain. For this, we use a powerful model organism - the nematode C. elegans - to study the genetics of behaviors that rely on neuromodulators such as serotonin, dopamine, and neuropeptides. Our research program also encompasses efforts to use the simple behaviors of C. elegans to discover novel neuroactive compounds that target neuromodulation in vivo.

Phone

212-263-3753

Academic office

540-562 First Avenue

Second Floor

New York, NY 10016

Lab Website
Ringstad Lab
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Positions

Professor, Department of Cell Biology at NYU Grossman School of Medicine

Vice Chair, Research, Department of Cell Biology

Graduate Education

PhD from Yale University

Postdoctoral Training

MIT, Horvitz Laboratory

Food sensing controls C. elegans reproductive behavior by neuromodulatory disinhibition

Chen, Yen-Chih; Zang, Kara E; Ahamed, Hassan; Ringstad, Niels

Science advances. 2025 Apr 18; 11(16):eadu5829

Chemosensory detection of polyamine metabolites guides C. elegans to nutritive microbes

Brissette, Benjamin; Ficaro, Lia; Li, Chenguang; Jones, Drew R; Ramanathan, Sharad; Ringstad, Niels

Science advances. 2024 Mar 22; 10(12):eadj4387

SAMPL is a high-throughput solution to study unconstrained vertical behavior in small animals

Zhu, Yunlu; Auer, Franziska; Gelnaw, Hannah; Davis, Samantha N; Hamling, Kyla R; May, Christina E; Ahamed, Hassan; Ringstad, Niels; Nagel, Katherine I; Schoppik, David

Cell reports. 2023 Jun 01; 42(6):112573

High-fidelity encoding of mechanostimuli by tactile food-sensing neurons requires an ensemble of ion channels

Fok, Alice; Brissette, Benjamin; Hallacy, Tim; Ahamed, Hassan; Ho, Elver; Ramanathan, Sharad; Ringstad, Niels

Cell reports. 2023 Apr 28; 42(5):112452

Opponent vesicular transporters regulate the strength of glutamatergic neurotransmission in a C. elegans sensory circuit

Choi, Jung-Hwan; Horowitz, Lauren Bayer; Ringstad, Niels

Nature communications. 2021 Nov 03; 12(1):6334

A microbial metabolite synergizes with endogenous serotonin to trigger C. elegans reproductive behavior

Chen, Yen-Chih; Seyedsayamdost, Mohammad R; Ringstad, Niels

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2020 Dec 01; 117(48):30589-30598

Development of specialized sensory neurons engages a nuclear receptor required for functional plasticity

Rossillo, Mary; Ringstad, Niels

Genes & development. 2020 Dec 01; 34(23-24):1666-1679

Insulin-like Peptides as Agents of Social Change

Brissette, Benjamin; Ringstad, Niels

Neuron. 2019 Dec 18; 104(6):1027-1028

See All Publications (38)

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