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Nigel W. Bunnett, PhD

Professor, Department of Neuroscience and Physiology

Positions

Professor, Department of Neuroscience and Physiology at NYU Grossman School of Medicine

Graduate Education

PhD from Cambridge University

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Protease-Activated Receptors in Health and Disease

Peach, Chloe J; Edgington-Mitchell, Laura E; Bunnett, Nigel W; Schmidt, Brian L

Physiological reviews. 2023 Jan 01; 103(1):717-785

The contribution of endocytosis to sensitization of nociceptors and synaptic transmission in nociceptive circuits

Tonello, Raquel; Anderson, Wayne B; Davidson, Steve; Escriou, Virginie; Yang, Lei; Schmidt, Brian L; Imlach, Wendy L; Bunnett, Nigel W

Pain. 2022 Nov 14;

Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain

Latorre, Rocco; Ramírez-Garcia, Paulina D; Hegron, Alan; Grace, James L; Retamal, Jeffri S; Shenoy, Priyank; Tran, Mai; Aurelio, Luigi; Flynn, Bernard; Poole, Daniel P; Klein-Cloud, Rafael; Jensen, Dane D; Davis, Thomas P; Schmidt, Brian L; Quinn, John F; Whittaker, Michael R; Veldhuis, Nicholas A; Bunnett, Nigel W

Biomaterials. 2022 Apr 28; 285:121536

Opioid-Induced Pronociceptive Signaling in the Gastrointestinal Tract Is Mediated by Delta-Opioid Receptor Signaling

Jaramillo-Polanco, Josue; Lopez-Lopez, Cintya; Yu, Yang; Neary, Emma; Hegron, Alan; Canals, Meritxell; Bunnett, Nigel W; Reed, David E; Lomax, Alan E; Vanner, Stephen J

Journal of neuroscience. 2022 04 20; 42(16):3316-3328

Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects

Jiménez-Vargas, Nestor Nivardo; Yu, Yang; Jensen, Dane D; Bok, Diana Daeun; Wisdom, Matthew; Latorre, Rocco; Lopez, Cintya; Jaramillo-Polanco, Josue O; Degro, Claudius; Guzman-Rodriguez, Mabel; Tsang, Quentin; Snow, Zachary; Schmidt, Brian L; Reed, David E; Lomax, Alan Edward; Margolis, Kara Gross; Stein, Christoph; Bunnett, Nigel W; Vanner, Stephen J

Gut. 2022 Apr; 71(4):695-704

Oral cancer induced TRPV1 sensitization is mediated by PAR2 signaling in primary afferent neurons innervating the cancer microenvironment

Scheff, Nicole N; Wall, Ian M; Nicholson, Sam; Williams, Hannah; Chen, Elyssa; Tu, Nguyen H; Dolan, John C; Liu, Cheng Z; Janal, Malvin N; Bunnett, Nigel W; Schmidt, Brian L

Scientific reports. 2022 Mar 08; 12(1):4121

Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain

Latorre, Rocco; Hegron, Alan; Peach, Chloe J; Teng, Shavonne; Tonello, Raquel; Retamal, Jeffri S; Klein-Cloud, Rafael; Bok, Diana; Jensen, Dane D; Gottesman-Katz, Lena; Rientjes, Jeanette; Veldhuis, Nicholas A; Poole, Daniel P; Schmidt, Brian L; Pothoulakis, Charalabos H; Rankin, Carl; Xie, Ying; Koon, Hon Wai; Bunnett, Nigel W

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2022 Feb 08; 119(6):

Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice

De Logu, Francesco; Nassini, Romina; Hegron, Alan; Landini, Lorenzo; Jensen, Dane D; Latorre, Rocco; Ding, Julia; Marini, Matilde; Souza Monteiro de Araujo, Daniel; Ramírez-Garcia, Paulina; Whittaker, Michael; Retamal, Jeffri; Titiz, Mustafa; Innocenti, Alessandro; Davis, Thomas P; Veldhuis, Nicholas; Schmidt, Brian L; Bunnett, Nigel W; Geppetti, Pierangelo

Nature communications. 2022 02 03; 13(1):646

See All Publications (372)