As a researcher and professor of orthopaedic surgery, biochemistry, and molecular pharmacology at NYU School of Medicine, I am an expert in osteoarthritis, the extracellular matrix, hyaluronic acid, synovial fluid, and intra-articular injection therapies.
My work has spanned three related fields—medical applications of matrix polymers, orthopaedic medicine and injection devices, and recombinant botulinum neurotoxins. Dr. Joseph Zuckerman and I founded the Center for Clinical Research, where we began developing big data approaches to personalized musculoskeletal medicine.
I am the chief executive officer of CytoDel LLC, a biopharmaceutical company that was co-developed at NYU Langone. We have engineered recombinant derivatives of botulinum neurotoxin to create therapeutic fusion proteins designed to deliver single chain antibodies into neurons.
Throughout my career, I have been deeply involved in taking inventions from the laboratory and applying them to medical practice using preclinical testing, formulation, chemistry and manufacturing controls, clinical trial design, and regulatory compliance.
Research Professor, Department of Orthopaedic Surgery
Research Professor, Department of Biochemistry and Molecular Pharmacology
PhD from City College
Clinical rheumatology. 2017 Sep 14; ?-?
Neurotherapeutics. 2017 July; Conference:(19th):827
TSG-6-A DOUBLE-EDGED SWORD FOR OSTEOARTHRITIS [Meeting Abstract]
Osteoarthritis & cartilage. 2017 APR; 25:S45-S46
Scientific reports. 2017 Feb 21; 7:42923-42923
Scientific reports. 2016 Aug 03; 6:30429-30429
Journal of bone & joint surgery (American volume). 2015 Dec 02; 97(23):1921-1928
Clinical orthopaedics & related research. 2015 Dec; 473(12):3894-3902
American journal of medical quality. 2015 Sep-Oct; 30(5):484-488e2880