Associate Professor, Department of Pathology
Our laboratory focuses on identifying metabolic pathways that are altered in the transformed state, understanding how those pathways support transformation, and investigating the environmental, genetic and epigenetic contexts in which such pathways act. Of particular interest are investigating serine and glycine metabolism and iron-sulfur cluster metabolism as well as exploring the potential ways by which mutations in the mitochondrial genome support cellular transformation. We attack these problems with a combination of approaches that endeavor to push the boundaries of genetic screening, mammalian cell culture, and metabolomic methods. Visit our lab website at: http://possematolab.med.nyu.edu/
550 First Avenue
Smilow 611
New York, NY 10016
Associate Professor, Department of Pathology at NYU Grossman School of Medicine
PhD from Harvard University
Whitehead Institute, MIT, Sabatini Lab
Nature metabolism. 2023 Feb; 5(2):277-293
Molecular cell. 2020 Nov 19; 80(4):682-698.e7
Nature. 2017 11 30; 551(7682):639-643
Molecular cell. 2018 02 15; 69(4):610-621.e5
Nature. 2011 Aug 18; 476(7360):346-50
Nature. 2014 Apr 03; 508(7494):108-12
Ferroptosis in Health and Disease. [S.l.] : Springer International Publishing, 2019. p.215-237. (4508572)