Robert G. Baker

Robert G. Baker

Neuroscience Institute

Research Professor, Department of Neuroscience and Physiology

cranial motor systems in vertebrates

Our goals address the evolution, embryology, ethology, and neurophysiology of cranial motor systems in vertebrates. The comparative anatomy and physiology of the visual, vestibular, and oculomotor systems are major fields of interests with experimental emphasis largely directed towards brainstem and cerebellar circuitry underlying eye and head movement. Current research projects center on establishing the intrinsic properties of vestibular, reticular, and cerebellar neurons both in vitro and in vivo with special emphasis on their role in oculomotor performance and motor learning. We use various single-cell microelectrode techniques to correlate excitatory and inhibitory synaptic responses with motor behavior. In complementary work, we address the ontogenetic assembly of cranial sensorimotor systems with contemporary chemical, molecular, and anatomical probes. We are also studying neuroepithelial and mesodermal cell lineage, fate, and tissue development in shark, zebrafish, bird, and mouse embryos. We investigate when and how eye muscles, motoneurons, and vestibular neurons become spatially programmed and functionally specified to produce eye movements. Overall, these experiments are designed to define the processes that coordinate development of sensory/motor networks to provide new insights into genetic blueprints, neuronal specification, and the role of hindbrain segmentation.

These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication

Research Professor, Department of Neuroscience and Physiology

Gilland, E; Straka, H; Wong, T W; Baker, R; Zottoli, S J

Journal of comparative neurology. 2014 Jul 01; 522(10):2446-2464

Ma, Leung-Hang; Grove, Charlotte L; Baker, Robert

Nature communications. 2014 Jun 25; 5:4221-4221

Bianco, Isaac H; Ma, Leung-Hang; Schoppik, David; Robson, Drew N; Orger, Michael B; Beck, James C; Li, Jennifer M; Schier, Alexander F; Engert, Florian; Baker, Robert

Current biology. CB. 2012 Jul 24; 22(14):1285-1295

May, Paul J; Vidal, Pierre-Paul; Baker, Harriet; Baker, Robert

Journal of comparative neurology. 2012 Jul 01; 520(10):2218-2240

Chagnaud, BP; Zee, MC; Baker, R; Bass, AH

Journal of neurophysiology. 2012 Jun; 107(12):3528-3542

Ulrich, Florian; Ma, Leung-Hang; Baker, Robert G; Torres-Vazquez, Jesus

Developmental biology (Orlando). 2011 Sep 01; 357(1):134-151