Saran Jonas, MD

Clinical Professor, Department of Neurology

Professor Emeritus of Neurology, Department of Neurology

Keywords
prevention and treatment of stroke
Summary

Saran Jonas, M.D. and a multidisciplinary team of investigators are engaged in studies to prevent and treat stroke. At NYUMC/BHC the Clopidogrel vs. Aspirin in Patients at Risk of Ischemic Events (CAPRIE) is comparing a new antiplatelet agent, clopidogrel, to conventional therapy with aspirin in the prevention of recurrent stroke. Eligible patients are randomized within six months of ischemic stroke onset. The NASCET (North American Symptomatic Carotid Endartetectomy Trial) study at NYUMC/BH is random for endarterectomy or medical management within 3 months of event. TIA-minor stroke patients with 30-69% relevant carotid stenosis. The WARSS trial (Warfarin Aspirin Recurrent Stroke Study) at the New York Department of Veterans Affairs Medical Center compares the efficacy of aspirin and warfarin in stroke prevention. Eligible veterans must be enrolled within 30 days of ischemic stroke onset. Also at the New York VAMC, investigators are carrying out a study to refine the recognition of the effects (neuropsychological and other) of cerebral microemboli during cardiac surgery, in order to enhance the ability to use this situation to test neuroprotective drugs.

At Tisch Hospital the use of intra-arterial thrombolytic agents for the treatment of acute stroke is being evaluated in conjunction with the Department of Radiology. Eligible patients are assessed and treated as soon as possible within the first few hours of ischemic stroke symptoms. Two potential neuroprotective agents, lubelozole and eloprodil are also being tested and administered to patients within the first 6 hours of stroke onset.

 

Phone

212-263-7591

Academic office

462 First Avenue

Seventh Floor

New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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Clinical Professor, Department of Neurology

Professor Emeritus of Neurology, Department of Neurology

MD from Columbia University

Wu, Fen; Koenig, Karen L; Zeleniuch-Jacquotte, Anne; Jonas, Saran; Afanasyeva, Yelena; Wojcik, Oktawia P; Costa, Max; Chen, Yu

PLoS one. 2016; 11(2):e0149348-e0149348e0149348

Jonas, Saran; Grieco, Giacinto; Norman, Robert; Grumet, Surah; Kedan, Ilan

Ethnicity & inequalities in health & social care. 2014; 7(3):137-145

Li, Yong-Sheng; Shemmer, Benjamin; Stone, Eric; A Nardi, Michael; Jonas, Saran; Quartermain, David

Brain research. 2013 Apr 24; 1507:134-145

Li, Zongdong; Nardi, Michael A; Li, Yong-Sheng; Zhang, Wei; Pan, Ruimin; Dang, Suying; Yee, Herman; Quartermain, David; Jonas, Saran; Karpatkin, Simon

Blood. 2009 Jun 11; 113(24):6051-6060

Quartermain, David; Li, Yong-Sheng; Jonas, Saran

Neurological research. 2007 Jul; 29(5):469-475

Reply to the letter by Derendorf: Clinical trials and dipyridamole formulation selection [Letter]

Grieco, G; Jonas, S

Cerebrovascular diseases. 2007 Feb; 23(1):73-74