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Shane A. Liddelow

Shane A. Liddelow, PhD

Neuroscience Institute

Assistant Professor, Department of Neuroscience and Physiology

Assistant Professor, Department of Ophthalmology

Keywords
glia, astrocyte, neuroinflammation, neurodegeneration, Alzheimer's disease, blood-brain barrier

Phone

212-263-8114

Fax

212-263-9170

Academic office

Science Building, 435 East 30th Street

11th Floor, Room 1116

New York, NY 10016

Lab Website
Liddelow Lab
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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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Positions

Assistant Professor, Department of Neuroscience and Physiology at NYU Grossman School of Medicine

Assistant Professor, Department of Ophthalmology at NYU Grossman School of Medicine

Co-Director, Parekh Center for Interdisciplinary Neurology

Graduate Education

PhD from University of Melbourne

Postdoctoral Training

Stanford University, Barres Lab

Neurotoxic reactive astrocytes are induced by activated microglia

Liddelow, Shane A; Guttenplan, Kevin A; Clarke, Laura E; Bennett, Frederick C; Bohlen, Christopher J; Schirmer, Lucas; Bennett, Mariko L; Munch, Alexandra E; Chung, Won-Suk; Peterson, Todd C; Wilton, Daniel K; Frouin, Arnaud; Napier, Brooke A; Panicker, Nikhil; Kumar, Manoj; Buckwalter, Marion S; Rowitch, David H; Dawson, Valina L; Dawson, Ted M; Stevens, Beth; Barres, Ben A

Nature. 2017 01 26; 541(7638):481-487

Normal aging induces A1-like astrocyte reactivity

Clarke, Laura E; Liddelow, Shane A; Chakraborty, Chandrani; Münch, Alexandra E; Heiman, Myriam; Barres, Ben A

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2018 02 20; 115(8):E1896-E1905

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

Shi, Yang; Yamada, Kaoru; Liddelow, Shane Antony; Smith, Scott T; Zhao, Lingzhi; Luo, Wenjie; Tsai, Richard M; Spina, Salvatore; Grinberg, Lea T; Rojas, Julio C; Gallardo, Gilbert; Wang, Kairuo; Roh, Joseph; Robinson, Grace; Finn, Mary Beth; Jiang, Hong; Sullivan, Patrick M; Baufeld, Caroline; Wood, Michael W; Sutphen, Courtney; McCue, Lena; Xiong, Chengjie; Del-Aguila, Jorge L; Morris, John C; Cruchaga, Carlos; Fagan, Anne M; Miller, Bruce L; Boxer, Adam L; Seeley, William W; Butovsky, Oleg; Barres, Ben A; Paul, Steven M; Holtzman, David M

Nature. 2017 09 28; 549(7673):523-527

Author Correction: Longitudinal scRNA-seq analysis in mouse and human informs optimization of rapid mouse astrocyte differentiation protocols

Frazel, Paul W; Labib, David; Fisher, Theodore; Brosh, Ran; Pirjanian, Nicolette; Marchildon, Anne; Boeke, Jef D; Fossati, Valentina; Liddelow, Shane A

Nature neuroscience. 2023 Nov 23;

Longitudinal scRNA-seq analysis in mouse and human informs optimization of rapid mouse astrocyte differentiation protocols

Frazel, Paul W; Labib, David; Fisher, Theodore; Brosh, Ran; Pirianian, Nicolette; Marchildon, Anne; Boeke, Jef D; Fossati, Valentina; Liddelow, Shane A

Nature neuroscience. 2023 Oct; 26(10):1726-1738

Determinants of motor neuron functional subtypes important for locomotor speed

D'Elia, Kristen P; Hameedy, Hanna; Goldblatt, Dena; Frazel, Paul; Kriese, Mercer; Zhu, Yunlu; Hamling, Kyla R; Kawakami, Koichi; Liddelow, Shane A; Schoppik, David; Dasen, Jeremy S

Cell reports. 2023 Sep 26; 42(9):113049

Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration

Patani, Rickie; Hardingham, Giles E; Liddelow, Shane A

Nature reviews. Neurology. 2023 Jul; 19(7):395-409

Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease

Castranio, Emilie L; Hasel, Philip; Haure-Mirande, Jean-Vianney; Ramirez Jimenez, Angie V; Hamilton, B Wade; Kim, Rachel D; Glabe, Charles G; Wang, Minghui; Zhang, Bin; Gandy, Sam; Liddelow, Shane A; Ehrlich, Michelle E

Alzheimer's & dementia. 2023 Jun; 19(6):2239-2252

See All Publications (83)

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