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Shruti Naik

Shruti Naik, PhD

Assistant Professor, Department of Pathology

Assistant Professor, Department of Medicine

Assistant Professor, Ronald O. Perelman Department of Dermatology

Immunology, Stem Cell Biology, Host-Microbe Interactions, Regeneration, Cancer, Development, Epithelial Biology

My laboratory studies the dynamic interactions between immune cells, epithelial cells, and microbes in barrier tissues that interface with the environment such as the skin, lungs, and gut. We navigate these complex biological systems with an interdisciplinary approach that draws from the fields immunology, microbiology, stem cell and developmental biology, and cancer biology. As such, the lab focuses on 3 major areas of research: 1) Inflammation, tissue regeneration and cancer,  2) host-microbe interactions, and 3) early in life immunity. 

Furthermore, we are able to leverage the abundant clinical resources of NYU Langone to translate our bench side findings to understand human immunity and its role in health and disease. This unique position allows us to delve deep into the biology of disease to fundamentally advance our knowledge of how the immune system works and identify the factors that cause immune reactions to go awry.  We then use this information to devise novel therapeutic strategies in a range of inflammatory epithelial conditions such as psoriasis, chronic wounds, and cancer.  



Academic office

435 East 30th St , Science Building

4th Floor, Room 414

New York , NY 10016

Lab Website
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PhD from University of Pennsylvania

The Rockefeller University , Laboratory of Mammalian Cell Biology and Development

Konieczny, Piotr; Naik, Shruti

Journal of investigative dermatology. 2020 Jun 10;

Mansfield, Kody; Naik, Shruti

Yale journal of biology & medicine. 2020 Mar; 93(1):133-143

Xing, Yue; Naik, Shruti

Cell host & microbe. 2019 Dec 11; 26(6):705-707

Jordan, Stefan; Tung, Navpreet; Casanova-Acebes, Maria; Chang, Christie; Cantoni, Claudia; Zhang, Dachuan; Wirtz, Theresa H; Naik, Shruti; Rose, Samuel A; Brocker, Chad N; Gainullina, Anastasiia; Hornburg, Daniel; Horng, Sam; Maier, Barbara B; Cravedi, Paolo; LeRoith, Derek; Gonzalez, Frank J; Meissner, Felix; Ochando, Jordi; Rahman, Adeeb; Chipuk, Jerry E; Artyomov, Maxim N; Frenette, Paul S; Piccio, Laura; Berres, Marie-Luise; Gallagher, Emily J; Merad, Miriam

Cell. 2019 Aug 22; 178(5):1102-1114.e17

Cataisson, Christophe; Salcedo, Rosalba; Michalowski, Aleksandra M; Klosterman, Mary; Naik, Shruti; Li, Luowei; Pan, Michelle J; Sweet, Amalia; Chen, Jin-Qiu; Kostecka, Laurie G; Karwan, Megan; Smith, Loretta; Dai, Ren-Ming; Stewart, C Andrew; Lyakh, Lyudmila; Hsieh, Wang-Ting; Khan, Asra; Yang, Howard; Lee, Maxwell; Trinchieri, Giorgio; Yuspa, Stuart H

Molecular cancer research. 2019 Aug; 17(8):1759-1773

Bukhari, Shoiab; Mertz, Aaron F; Naik, Shruti

International immunology. 2019 Jul 13; 31(7):415-422

Kobayashi, Tetsuro; Naik, Shruti; Nagao, Keisuke

Immunity. 2019 Mar 19; 50(3):552-565

Paller, Amy S; Kong, Heidi H; Seed, Patrick; Naik, Shruti; Scharschmidt, Tiffany C; Gallo, Richard L; Luger, Thomas; Irvine, Alan D

Journal of allergy & clinical immunology. 2019 Jan; 143(1):26-35