My laboratory studies the dynamic interactions between immune cells, epithelial cells, and microbes in barrier tissues that interface with the environment such as the skin, lungs, and gut. We navigate these complex biological systems with an interdisciplinary approach that draws from the fields immunology, microbiology, stem cell and developmental biology, and cancer biology. As such, the lab focuses on 3 major areas of research: 1) Inflammation, tissue regeneration and cancer, 2) host-microbe interactions, and 3) early in life immunity.
Furthermore, we are able to leverage the abundant clinical resources of the NYU medical center to translate our bench side findings to understand human immunity and its role in health and disease. This unique position allows us to delve deep into the biology of disease to fundamentally advance our knowledge of how the immune system works and identify the factors that cause immune reactions to go awry. We then use this information to devise novel therapeutic strategies in a range of inflammatory epithelial conditions such as psoriasis, chronic wounds, and cancer.
Assistant Professor, Department of Pathology
Assistant Professor, Department of Medicine
Assistant Professor, Ronald O. Perelman Department of Dermatology
PhD from University of Pennsylvania
The Rockefeller University , Laboratory of Mammalian Cell Biology and Development
Nature medicine. 2018 Sep; 24(9):1311-1312
Nature. 2018 Aug; 560(7716):E2-E2
Nature. 2017 Oct 26; 550(7677):475-480
Developmental cell. 2017 Jun 05; 41(5):455-456
Nature. 2017 Jan 26; 541(7638):494-499
Cell. 2016 Nov 17; 167(5):1323-1338.e14
Experimental dermatology. 2016 Nov; 25(11):917-932
Journal of immunology (1950). 2015 Dec 15; 195(12):5837-5838