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Shruti Naik

Shruti Naik, PhD

Associate Professor, Department of Pathology

Associate Professor, Department of Medicine

Associate Professor, Ronald O. Perelman Department of Dermatology

Immunology, Stem Cell Biology, Host-Microbe Interactions, Regeneration, Cancer, Development, Epithelial Biology

My laboratory studies the dynamic interactions between immune cells, epithelial cells, and microbes in barrier tissues that interface with the environment such as the skin, lungs, and gut. We navigate these complex biological systems with an interdisciplinary approach that draws from the fields immunology, microbiology, stem cell and developmental biology, and cancer biology. As such, the lab focuses on 3 major areas of research: 1) Inflammation, tissue regeneration and cancer,  2) host-microbe interactions, and 3) early in life immunity. 

Furthermore, we are able to leverage the abundant clinical resources of NYU Langone to translate our bench side findings to understand human immunity and its role in health and disease. This unique position allows us to delve deep into the biology of disease to fundamentally advance our knowledge of how the immune system works and identify the factors that cause immune reactions to go awry.  We then use this information to devise novel therapeutic strategies in a range of inflammatory epithelial conditions such as psoriasis, chronic wounds, and cancer.  



Academic office

435 East 30th St , Science Building

4th Floor, Room 414

New York , NY 10016

Lab Website
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Associate Director, Judith & StewartColton Center for Autoimmunity

PhD from University of Pennsylvania

The Rockefeller University , Laboratory of Mammalian Cell Biology and Development

Major, Jack; Naik, Shruti

Cell. 2023 Nov 22; 186(24):5201-5202

Konieczny, Piotr; Naik, Shruti

Cell stem cell. 2023 Oct 05; 30(10):1283-1284

Castillo, Rochelle L; Sidhu, Ikjot; Dolgalev, Igor; Chu, Tinyi; Prystupa, Aleksandr; Subudhi, Ipsita; Yan, Di; Konieczny, Piotr; Hsieh, Brandon; Haberman, Rebecca H; Selvaraj, Shanmugapriya; Shiomi, Tomoe; Medina, Rhina; Girija, Parvathy Vasudevanpillai; Heguy, Adriana; Loomis, Cynthia A; Chiriboga, Luis; Ritchlin, Christopher; Garcia-Hernandez, Maria De La Luz; Carucci, John; Meehan, Shane A; Neimann, Andrea L; Gudjonsson, Johann E; Scher, Jose U; Naik, Shruti

Science immunology. 2023 Jun 08; 8(84):eabq7991

McKinley, Kara L; Longaker, Michael T; Naik, Shruti

Science. 2023 May 26; 380(6647):796-798

Guenin-Mace, Laure; Konieczny, Piotr; Naik, Shruti

Annual review of immunology. 2023 Apr 26; 41:207-228

Kratofil, Rachel M; Naik, Shruti

Journal of experimental medicine. 2023 Mar 06; 220(3):

Wasko, Renee; Bridges, Kate; Pannone, Rebecca; Sidhu, Ikjot; Xing, Yue; Naik, Shruti; Miller-Jensen, Kathryn; Horsley, Valerie

Developmental cell. 2022 Dec 19; 57(24):2699-2713.e5

Konieczny, Piotr; Xing, Yue; Sidhu, Ikjot; Subudhi, Ipsita; Mansfield, Kody P; Hsieh, Brandon; Biancur, Douglas E; Larsen, Samantha B; Cammer, Michael; Li, Dongqing; Landén, Ning Xu; Loomis, Cynthia; Heguy, Adriana; Tikhonova, Anastasia N; Tsirigos, Aristotelis; Naik, Shruti

Science. 2022 07 08; 377(6602):eabg9302