Sophie M. Morgani, PhD

My research is centered on elucidating the factors that affect the function of skeletal stem cells, which play a pivotal role in the maintenance and repair of bone tissue.

With advancing age, there is a decrease in the number and osteogenic function of skeletal stem cells resulting in increased bone fragility, compromised healing processes, and the onset of osteoporosis. The principal objective of my studies is to understand the cell-intrinsic and extrinsic factors that bring about this decline to facilitate the development of effective therapies to rejuvenate the aged skeleton.