Sophie M. Morgani

Sophie M. Morgani, PhD

Research Assistant Professor, Department of Orthopedic Surgery

Keywords
skeletal stem cells, bone, osteoporosis, aging, fracture, regeneration
Summary

My research is centered on elucidating the factors that affect the function of skeletal stem cells, which play a pivotal role in the maintenance and repair of bone tissue.

With advancing age, there is a decrease in the number and osteogenic function of skeletal stem cells resulting in increased bone fragility, compromised healing processes, and the onset of osteoporosis. The principal objective of my studies is to understand the cell-intrinsic and extrinsic factors that bring about this decline to facilitate the development of effective therapies to rejuvenate the aged skeleton.

 

Academic office

550 1st Avenue , Medical Science Building

2, 255E

New York, NY 10016

Lab Website
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PhD from University of Edinburgh

University of Copenhagen, Danish Stem Cell Center / Brickman Lab

Memorial Sloan Kettering Cancer Center , Developmental Biology Program / Hadjantonakis Lab

NYU Langone, NYU Department of Orthopedic Surgery / Leucht Lab

Remark, Lindsey H; Leclerc, Kevin; Ramsukh, Malissa; Lin, Ziyan; Lee, Sooyeon; Dharmalingam, Backialakshmi; Gillinov, Lauren; Nayak, Vasudev V; El Parente, Paulo; Sambon, Margaux; Atria, Pablo J; Ali, Mohamed A E; Witek, Lukasz; Castillo, Alesha B; Park, Christopher Y; Adams, Ralf H; Tsirigos, Aristotelis; Morgani, Sophie M; Leucht, Philipp

Bone research. 2023 Sep 27; 11(1):50

Loder, Shawn; Patel, Nicole; Morgani, Sophie; Sambon, Margaux; Leucht, Philipp; Levi, Benjamin

Bone. 2023 Aug; 173:116777

Leclerc, Kevin; Remark, Lindsey H; Ramsukh, Malissa; Josephson, Anne Marie; Palma, Laura; Parente, Paulo E L; Sambon, Margaux; Lee, Sooyeon; Lopez, Emma Muiños; Morgani, Sophie M; Leucht, Philipp

Development. 2023 Mar 15; 150(6):

Lopez, Emma Muiños; Leclerc, Kevin; Ramsukh, Malissa; Parente, Paulo El; Patel, Karan; Aranda, Carlos J; Josephson, Anna M; Remark, Lindsey H; Kirby, David J; Buchalter, Daniel B; Hadi, Tarik; Morgani, Sophie M; Ramkhelawon, Bhama; Leucht, Philipp

Bone. 2022 Jan 06; 157:116324

Morgani, Sophie M; Hadjantonakis, Anna-Katerina

Biology open. 2021 May 15; 10(5):

Morgani, Sophie M; Hadjantonakis, Anna-Katerina

Biology open. 2021 May 15; 10(5):

Morgani, Sophie M; Su, Jie; Nichols, Jennifer; Massagué, Joan; Hadjantonakis, Anna-Katerina

eLife. 2021 Apr 30; 10:

Morgani, Sophie M; Hadjantonakis, Anna-Katerina

Methods in molecular biology. 2021 Jan; 2214:41-58