Sounak Sahu, PhD

Interim Member of the Faculty, Department of Cell Biology

Positions

Interim Member of the Faculty, Department of Cell Biology at NYU Grossman School of Medicine

Graduate Education

PhD from Oxford University

Postdoctoral Training

National Cancer Institute, NIH, Mouse Cancer Genetics Program

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Saturation genome editing-based clinical classification of BRCA2 variants

Sahu, Sounak; Galloux, Melissa; Southon, Eileen; Caylor, Dylan; Sullivan, Teresa; Arnaudi, Matteo; Zanti, Maria; Geh, Josephine; Chari, Raj; Michailidou, Kyriaki; Papaleo, Elena; Sharan, Shyam K

Nature. 2025 Feb; 638(8050):538-545

Spatiotemporal modulation of growth factors directs the generation of multilineage mouse embryonic stem cell-derived mammary organoids

Sahu, Sounak; Sahoo, Sarthak; Sullivan, Teresa; O'Sullivan, T Norene; Turan, Sevilay; Albaugh, Mary E; Burkett, Sandra; Tran, Bao; Salomon, David S; Kozlov, Serguei V; Koehler, Karl R; Jolly, Mohit Kumar; Sharan, Shyam K

Developmental cell. 2024 Jan 22; 59(2):175-186.e8

Protocol for the saturation and multiplexing of genetic variants using CRISPR-Cas9

Sahu, Sounak; Sullivan, Teresa; Southon, Eileen; Caylor, Dylan; Geh, Josephine; Sharan, Shyam K

STAR protocols. 2023 Dec 15; 4(4):102702

Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs

Biswas, Kajal; Mitrophanov, Alexander Y; Sahu, Sounak; Sullivan, Teresa; Southon, Eileen; Nousome, Darryl; Reid, Susan; Narula, Sakshi; Smolen, Julia; Sengupta, Trisha; Riedel-Topper, Maximilian; Kapoor, Medha; Babbar, Anav; Stauffer, Stacey; Cleveland, Linda; Tandon, Mayank; Malys, Tyler; Sharan, Shyam K

Cell reports methods. 2023 Nov 20; 3(11):100628

Characterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant

Mishra, Arun Prakash; Hartford, Suzanne; Chittela, Rajani Kant; Sahu, Sounak; Kharat, Suhas S; Alvaro-Aranda, Lucia; Contreras-Perez, Aida; Sullivan, Teresa; Martin, Betty K; Albaugh, Mary; Southon, Eileen; Burkett, Sandra; Karim, Baktiar; Carreira, Aura; Tessarollo, Lino; Sharan, Shyam K

Cell death & disease. 2023 Nov 18; 14(11):753

CRISPR-based precision medicine for hematologic disorders: Advancements, challenges, and prospects

Sahu, Sounak; Poplawska, Maria; Lim, Seah H; Dutta, Dibyendu

Life sciences. 2023 Nov 15; 333:122165

Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants

Sahu, Sounak; Sullivan, Teresa L; Mitrophanov, Alexander Y; Galloux, Mélissa; Nousome, Darryl; Southon, Eileen; Caylor, Dylan; Mishra, Arun Prakash; Evans, Christine N; Clapp, Michelle E; Burkett, Sandra; Malys, Tyler; Chari, Raj; Biswas, Kajal; Sharan, Shyam K

PLoS genetics. 2023 Sep; 19(9):e1010940

Growth factor dependency in mammary organoids regulates ductal morphogenesis during organ regeneration

Sahu, Sounak; Albaugh, Mary E; Martin, Betty K; Patel, Nimit L; Riffle, Lisa; Mackem, Susan; Kalen, Joseph D; Sharan, Shyam K

Scientific reports. 2022 May 03; 12(1):7200

See All Publications (17)