Sylvia Lee-Huang

Sylvia Lee-Huang, PhD

Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
Viral Infection, Biomarkers, Anti-HIV Agents, Regulation of Gene Expression, Isolation, Purification and Cloning of Human Erythropoietin, Interactions of DNA, RNA, Polynucleotides with Metal Ions, Polyamines and Proteins, Small RNAs, Ribosomes, Initiation Factors in Protein Biosynthesis, Antiviral and Antitumor Agents from Nature Products and Medicinal Plants
Summary

Dr. Sylvia Lee-Huang has a broad background in biochemistry, biophysics, cell biology, molecular biology, molecular genetics and virology. She received her training in molecular biology/biochemistry with Nobel laureate Severo Ochoa in the Department of Biochemistry at New York University School of Medicine. She is globally renowned for proposing and providing experimental evidence for the reversed flow of genetic information from RNA to DNA and for the discovery of small regulatory RNAs and messenger specific initiation factors. Dr. Lee Huang's lab was the first to clone and express human erythropoietin. The lab isolated, purified, characterized and elucidated the mechanism of anti-HIV proteins, oligopeptides, and small molecules.

Phone

212-263-5135

Academic office

455 First Avenue, Public Health Bldg.

8, 840

New York, NY 10016

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Positions

Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Graduate Education

PhD from University of Pittsburgh

The ribosome-inactivating proteins MAP30 and Momordin inhibit SARS-CoV-2

Watts, Norman R; Eren, Elif; Palmer, Ira; Huang, Paul L; Huang, Philip Lin; Shoemaker, Robert H; Lee-Huang, Sylvia; Wingfield, Paul T

PLoS one. 2023; 18(6):e0286370

Endothelial Nitric Oxide Synthase Knockdown in Human Stem Cells Impacts Mitochondrial Biogenesis and Adipogenesis: Live-Cell Real-Time Fluorescence Imaging

Lee-Huang, Sylvia; Huang, Philip Lin; Huang, Paul Lee

Journal of clinical medicine. 2021 Feb 07; 10(4):

Live-Cell Real-Time Imaging of Mitochondria in HIV-1-Infected Cells

Lee-Huang, Sylvia; Huang, Philip Lin; Huang, Paul Lee

AIDS research & human retroviruses. 2014 Nov; 30(11):1025-6

Oleuropein and Related Compounds from Olive Plants Modulate Adipogenesis

Lee-Huang, Sylvia; Huang, Philip L; Zhang, Dawei, Lee, Jae Wook; Chang, Young-Tae; Zhang, John; Huang, Paul L

Open conference proceedings journal. 2013; 4:113-124

The Discovery of MAP30 and Elucidation of its Medicinal Activities

Lee-Huang, Sylvia; Huang, Philip Lin; Huang, Paul Lee

Antitumor potential and other emerging medicinal properties of natural compounds. Dordrecht ; New York : Springer, cop. 2013. p.117-126. (2089102)

Live-cell real-time imaging reveals role of mitochondria in cell-to-cell transmission of HIV-1

Lee-Huang, Sylvia; Lin Huang, Philip; Lee Huang, Paul

Biochemical & biophysical research communications. 2011 Nov 18; 415(2):384-9

Computational study of bindings of HL9, a nonapeptide fragment of human lysozyme, to HIV-1 fusion protein gp41

Hartono, Yossa Dwi; Lee, Angelina Noviani; Lee-Huang, Sylvia; Zhang, Dawei

Bioorganic & medicinal chemistry letters. 2011 Mar 15; 21(6):1607-11

COMPUTATIONAL DESIGN OF NORBORNANE-BASED HIV-1 PROTEASE INHIBITORS

Zhang, DW; Yu, LZ; Huang, PL; Lee-Huang, S; Zhang, JZH

Journal of theoretical & computational chemistry. 2010 Apr; 9(2):471-485

See All Publications (99)