Teresa Davoli

Teresa Davoli, PhD

Institute for Systems Genetics

Associate Professor, Department of Biochemistry and Molecular Pharmacology

Summary

What are the causes and consequences of genomic copy number alterations (i.e. aneuploidy) in cancer? How does aneuploidy affect patients’ response to therapy, especially immuno-therapy? How do protein complexes form in normal cells and how is this process affected by aneuploidy?
These are among the main questions our Lab is interested in. To answer these questions, we utilize a variety of experimental and computational approaches, from large-scale genetic screens in human cells to prediction of survival in cancer patients.

Phone

212-263-8081

Academic office

NYU Langone Health, 435 East 30th Street

9th floor, Room 904

Lab Website
Davoli Lab
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Positions

Associate Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Graduate Education

PhD from Rockefeller University

PARP1 suppression drives ROS resistance in aneuploid cancer cells

Cheng, Pan; Mermerian-Baghdassarian, Angela; Wang, Yufeng; Chen, Ze; Quysbertf, Helberth M; Cheema, Pradeep Singh; Mays, Joseph C; Zhao, Xin; Katsnelson, Lizabeth; Mei, Sally; Shrivastava, Rohini; Bulatovic, Mirna; Deng, Jiehui; Schober, Markus; Wong, Kwok-Kin; Davoli, Teresa

Molecular cell. 2026 May 07; 86(9):1742-1761.e19

The role of retrotransposons at the interface of DNA damage and the innate immune response

Vikraman, Pooja; Davoli, Teresa; Mita, Paolo

Current opinion in cell biology. 2026 Apr; 99:102625

Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation

Lee, Sophia N; Banda, Erin C; Qiao, Lu; Thompson, Sarah L; Singh, Karan; Hagenson, Ryan A; Davoli, Teresa; Pinter, Stefan F; Sheltzer, Jason M

Genome research. 2026 Mar 02; 36(3):547-560

Modeling and targeting general and chromosome-specific aneuploidy in cancer

Goldberg, Aleah; Trifas, Maria; Davoli, Teresa

Genes & development. 2025 Oct 01; 39(19-20):1132-1154

Interferon-ε loss is elusive 9p21 link to immune-cold tumors, resistant to immune-checkpoint therapy and endogenous CXCL9/10 induction

Zhao, Xin; Liu, Bin; William, William N; Tsanov, Kaloyan M; Ho, Yu-Jui; Barriga, Francisco M; Lim, Raymond J; Trifas, Maria; Du, Yushen; Lowe, Scott W; Dubinett, Steven M; Davoli, Teresa; Lippman, Scott M

Journal of thoracic oncology. 2025 Sep; 20(9):1177-1236

The Hallmarks of Aneuploidy in Cancer and Congenital Syndromes

Cheng, Pan; Singh, Karan; Reeves, Roger H; Davoli, Teresa

Annual review of genomics & human genetics. 2025 Aug; 26(1):103-138

Proteogenomic insights suggest druggable pathways in endometrial carcinoma

Dou, Yongchao; Katsnelson, Lizabeth; Gritsenko, Marina A; Hu, Yingwei; Reva, Boris; Hong, Runyu; Wang, Yi-Ting; Kolodziejczak, Iga; Lu, Rita Jui-Hsien; Tsai, Chia-Feng; Bu, Wen; Liu, Wenke; Guo, Xiaofang; An, Eunkyung; Arend, Rebecca C; Bavarva, Jasmin; Chen, Lijun; Chu, Rosalie K; Czekański, Andrzej; Davoli, Teresa; Demicco, Elizabeth G; DeLair, Deborah; Devereaux, Kelly; Dhanasekaran, Saravana M; Dottino, Peter; Dover, Bailee; Fillmore, Thomas L; Foxall, McKenzie; Hermann, Catherine E; Hiltke, Tara; Hostetter, Galen; Jędryka, Marcin; Jewell, Scott D; Johnson, Isabelle; Kahn, Andrea G; Ku, Amy T; Kumar-Sinha, Chandan; Kurzawa, Paweł; Lazar, Alexander J; Lazcano, Rossana; Lei, Jonathan T; Li, Yi; Liao, Yuxing; Lih, Tung-Shing M; Lin, Tai-Tu; Martignetti, John A; Masand, Ramya P; Matkowski, Rafał; McKerrow, Wilson; Mesri, Mehdi; Monroe, Matthew E; Moon, Jamie; Moore, Ronald J; Nestor, Michael D; Newton, Chelsea; Omelchenko, Tatiana; Omenn, Gilbert S; Payne, Samuel H; Petyuk, Vladislav A; Robles, Ana I; Rodriguez, Henry; Ruggles, Kelly V; Rykunov, Dmitry; Savage, Sara R; Schepmoes, Athena A; Shi, Tujin; Shi, Zhiao; Tan, Jimin; Taylor, Mason; Thiagarajan, Mathangi; Wang, Joshua M; Weitz, Karl K; Wen, Bo; Williams, C M; Wu, Yige; Wyczalkowski, Matthew A; Yi, Xinpei; Zhang, Xu; Zhao, Rui; Mutch, David; Chinnaiyan, Arul M; Smith, Richard D; Nesvizhskii, Alexey I; Wang, Pei; Wiznerowicz, Maciej; Ding, Li; Mani, D R; Zhang, Hui; Anderson, Matthew L; Rodland, Karin D; Zhang, Bing; Liu, Tao; Fenyö, David; ,

Cancer cell. 2023 Sep 11; 41(9):1586-1605.e15

KaryoCreate: A CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres

Bosco, Nazario; Goldberg, Aleah; Zhao, Xin; Mays, Joseph C; Cheng, Pan; Johnson, Adam F; Bianchi, Joy J; Toscani, Cecilia; Di Tommaso, Elena; Katsnelson, Lizabeth; Annuar, Dania; Mei, Sally; Faitelson, Roni E; Pesselev, Ilan Y; Mohamed, Kareem S; Mermerian, Angela; Camacho-Hernandez, Elaine M; Gionco, Courtney A; Manikas, Julie; Tseng, Yi-Shuan; Sun, Zhengxi; Fani, Somayeh; Keegan, Sarah; Lippman, Scott M; Fenyö, David; Giunta, Simona; Santaguida, Stefano; Davoli, Teresa

Cell. 2023 Apr 27; 186(9):1985-2001.e19

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