Institute for Systems Genetics
Assistant Professor, Department of Biochemistry and Molecular Pharmacology
What are the causes and consequences of genomic copy number alterations (i.e. aneuploidy) in cancer? How does aneuploidy affect patients’ response to therapy, especially immuno-therapy? How do protein complexes form in normal cells and how is this process affected by aneuploidy?
These are among the main questions our Lab is interested in. To answer these questions, we utilize a variety of experimental and computational approaches, from large-scale genetic screens in human cells to prediction of survival in cancer patients.
PhD from Rockefeller University
Cancer cell. 2023 Sep 11; 41(9):1586-1605.e15
Cell. 2023 Apr 27; 186(9):1985-2001.e19
Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2022 Nov 22; 119(47):e2213835119
Nature. 2022 Mar; 603(7902):728-735
Genetics. 2021 May 17; 218(1):
Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2021 May 11; 118(19):