Ting Chen

Ting Chen, PhD

Perlmutter Cancer Center

Research Assistant Professor, Department of Medicine

Summary

I have been working on molecular biology and drug development in oncology in an industrial setting including target identification, chemical scaffold optimization and animal models for more than 15 years. As the lab supervisor and industrial project manager, I am currently working with various lung cancer mouse models and drug test using GEMMs and xenograft through both academic (Harvard, MIT and MD Anderson etc.) and industrial (Novartis, AZ, Pfizer, GSK, Eli Lilly and Gilead etc.) collaborations. Meanwhile, I am utilizing a 3D culture new platform using patient biopsy samples for personalized treatment strategy. Main role involves research proposal and budgeting, group leading, project execution and management.

Phone

646-501-2849

Academic office

522 1st Ave SML1010

New York, NY 10016

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Positions

Research Assistant Professor, Department of Medicine at NYU Grossman School of Medicine

Graduate Education

PhD from Nanjing University

Postdoctoral Training

Harvard Medical School, Lab for Translational Research

Author Correction: Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer

Robichaux, Jacqulyne P; Elamin, Yasir Y; Tan, Zhi; Carter, Brett W; Zhang, Shuxing; Liu, Shengwu; Li, Shuai; Chen, Ting; Poteete, Alissa; Estrada-Bernal, Adriana; Le, Anh T; Truini, Anna; Nilsson, Monique B; Sun, Huiying; Roarty, Emily; Goldberg, Sarah B; Brahmer, Julie R; Altan, Mehmet; Lu, Charles; Papadimitrakopoulou, Vassiliki; Politi, Katerina; Doebele, Robert C; Wong, Kwok-Kin; Heymach, John V

Nature medicine. 2024 Sep; 30(9):2694-2695

FGFR inhibition augments anti-PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression

Okato, Atsushi; Utsumi, Takanobu; Ranieri, Michela; Zheng, Xingnan; Zhou, Mi; Pereira, Luiza D; Chen, Ting; Kita, Yuki; Wu, Di; Hyun, Hyesun; Lee, Hyojin; Gdowski, Andrew S; Raupp, John D; Clark-Garvey, Sean; Manocha, Ujjawal; Chafitz, Alison; Sherman, Fiona; Stephens, Janaye; Rose, Tracy L; Milowsky, Matthew I; Wobker, Sara E; Serody, Jonathan S; Damrauer, Jeffrey S; Wong, Kwok-Kin; Kim, William Y

Journal of clinical investigation. 2024 Jan 16; 134(2):

Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth

Rashidfarrokhi, Ali; Pillai, Ray; Hao, Yuan; Wu, Warren L; Karadal-Ferrena, Burcu; Dimitriadoy, Sofia G; Cross, Michael; Yeaton, Anna H; Huang, Shih Ming; Bhutkar, Arjun J; Herrera, Alberto; Rajalingam, Sahith; Hayashi, Makiko; Huang, Kuan-Lin; Bartnicki, Eric; Zavitsanou, Anastasia-Maria; Wohlhieter, Corrin A; Leboeuf, Sarah E; Chen, Ting; Loomis, Cynthia; Mezzano, Valeria; Kulicke, Ruth; Davis, Fred P; Stransky, Nicolas; Smolen, Gromoslaw A; Rudin, Charles M; Moreira, Andre L; Khanna, Kamal M; Pass, Harvey I; Wong, Kwok-Kin; Koide, Shohei; Tsirigos, Aristotelis; Koralov, Sergei B; Papagiannakopoulos, Thales

bioRxiv.org : the preprint server for biology. 2023 Jul 17;

Histone Deacetylase 6 Inhibition Exploits Selective Metabolic Vulnerabilities in LKB1 Mutant, KRAS Driven NSCLC

Zhang, Hua; Nabel, Christopher S; Li, Dezhi; O'Connor, Ruth Í; Crosby, Caroline R; Chang, Sarah M; Hao, Yuan; Stanley, Robyn; Sahu, Soumyadip; Levin, Daniel S; Chen, Ting; Tang, Sittinon; Huang, Hsin-Yi; Meynardie, Mary; Stephens, Janaye; Sherman, Fiona; Chafitz, Alison; Costelloe, Naoise; Rodrigues, Daniel A; Fogarty, Hilda; Kiernan, Miranda G; Cronin, Fiona; Papadopoulos, Eleni; Ploszaj, Magdalena; Weerasekara, Vajira; Deng, Jiehui; Kiely, Patrick; Bardeesy, Nabeel; Vander Heiden, Matthew G; Chonghaile, Triona Ni; Dowling, Catríona M; Wong, Kwok-Kin

Journal of thoracic oncology. 2023 Jul; 18(7):882-895

KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition

Pan, Yuanwang; Han, Han; Hu, Hai; Wang, Hua; Song, Yueqiang; Hao, Yuan; Tong, Xinyuan; Patel, Ayushi S; Misirlioglu, Selim; Tang, Sittinon; Huang, Hsin-Yi; Geng, Ke; Chen, Ting; Karatza, Angeliki; Sherman, Fiona; Labbe, Kristen E; Yang, Fan; Chafitz, Alison; Peng, Chengwei; Guo, Chenchen; Moreira, Andre L; Velcheti, Vamsidhar; Lau, Sally C M; Sui, Pengfei; Chen, Haiquan; Diehl, J Alan; Rustgi, Anil K; Bass, Adam J; Poirier, John T; Zhang, Xiaoyang; Ji, Hongbin; Zhang, Hua; Wong, Kwok-Kin

Cancer cell. 2023 Jan 09; 41(1):88-105.e8

Nemvaleukin alfa, a novel engineered IL-2 fusion protein, drives antitumor immunity and inhibits tumor growth in small cell lung cancer

Pan, Yuanwang; Hao, Yuan; Han, Han; Chen, Ting; Ding, Hailin; Labbe, Kristen E; Shum, Elaine; Guidry, Kayla; Hu, Hai; Sherman, Fiona; Geng, Ke; Stephens, Janaye; Chafitz, Alison; Tang, Sittinon; Huang, Hsin-Yi; Peng, Chengwei; Almonte, Christina; Lopes, Jared E; Losey, Heather C; Winquist, Raymond J; Velcheti, Vamsidhar; Zhang, Hua; Wong, Kwok-Kin

Journal for immunotherapy of cancer. 2022 Sep; 10(9):

Loss of TSC1/TSC2 sensitizes immune checkpoint blockade in non-small cell lung cancer

Huang, Qingyuan; Li, Fei; Hu, Hai; Fang, Zhaoyuan; Gao, Zhendong; Xia, Guozhan; Ng, Wai-Lung; Khodadadi-Jamayran, Alireza; Chen, Ting; Deng, Jiehui; Zhang, Hua; Almonte, Christina; Labbe, Kristen; Han, Han; Geng, Ke; Tang, Sittinon; Freeman, Gordon J; Li, Yuan; Chen, Haiquan; Wong, Kwok-Kin

Science advances. 2022 Feb 04; 8(5):eabi9533

Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC

Tang, Kwan Ho; Li, Shuai; Khodadadi-Jamayran, Alireza; Jen, Jayu; Han, Han; Guidry, Kayla; Chen, Ting; Hao, Yuan; Fedele, Carmine; Zebala, John A; Maeda, Dean Y; Christensen, James G; Olson, Peter; Athanas, Argus; Loomis, Cynthia A; Tsirigos, Aristotelis; Wong, Kwok-Kin; Neel, Benjamin G

Cancer discovery. 2022 Jan; 12(1):47-61

See All Publications (69)