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Tomas Kirchhoff, PhD

Perlmutter Cancer Center

Associate Professor, Department of Population Health

cancer, computational biology, epidemiology, genomics

The primary interest of my laboratory is focused on the identification of the genetic basis of cancer susceptibility. A key question in these efforts is how the germline genetic events contributing to predisposition of human cancers interact mutually in particular molecular pathways or in concert with the environmental exposures. Specifically, our ongoing studies aim at identification of the genetic variants conferring an increased risk to common cancers, such as breast, colon, prostate cancers or lymphoma, focusing on the relevant molecular pathways. These studies combine the genome-wide association analysis (GWAS), high-throughput genotyping and most recently the next-generation sequencing in large case/control populations. The significant aspect of my current and future research is an integration of the information from somatic genetics in tumors to complement the germline findings. We believe that such integration of biological data will be beneficial not only for improved prevention strategies but most importantly for the future development of the targeted personalized therapies.



Academic office

522 First Avenue

Twelfth Floor

New York, NY 10016

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication
*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

Memorial Sloan-Kettering Cancer Center, Clinical Cancer Genetics

Ibrahim, Milad; Illa-Bochaca, Irineu; Fa"™ak, Faisal; Monson, Kelsey R.; Ferguson, Robert; Lyu, Chen; Vega-Saenz de Miera, Eleazar; Johannet, Paul; Chou, Margaret; Mastroianni, Justin; Darvishian, Farbod; Kirchhoff, Tomas; Zhong, Judy; Krogsgaard, Michelle; Osman, Iman

Cancers. 2024 Jan 01; 16(<prism:issueIdentifier>1):?-?

Ferguson, Robert; Chat, Vylyny; Morales, Leah; Simpson, Danny; Monson, Kelsey R; Cohen, Elisheva; Zusin, Sarah; Madonna, Gabriele; Capone, Mariaelena; Simeone, Ester; Pavlick, Anna; Luke, Jason J; Gajewski, Thomas F; Osman, Iman; Ascierto, Paolo; Weber, Jeffrey; Kirchhoff, Tomas

European journal of cancer (1990). 2023 Aug; 189:112923

Ascierto, Paolo A; Avallone, Antonio; Bifulco, Carlo; Bracarda, Sergio; Brody, Joshua D; Emens, Leisha A; Ferris, Robert L; Formenti, Silvia C; Hamid, Omid; Johnson, Douglas B; Kirchhoff, Tomas; Klebanoff, Christopher A; Lesinski, Gregory B; Monette, Anne; Neyns, Bart; Odunsi, Kunle; Paulos, Chrystal M; Powell, Daniel J; Rezvani, Katayoun; Segal, Brahm H; Singh, Nathan; Sullivan, Ryan J; Fox, Bernard A; Puzanov, Igor

Journal of translational medicine. 2023 Jul 20; 21(1):488

Chat, Vylyny; Dagayev, Sasha; Moran, Una; Snuderl, Matija; Weber, Jeffrey; Ferguson, Robert; Osman, Iman; Kirchhoff, Tomas

Frontiers in oncology. 2023 Jan 19; 12:?-?

Khushalani, Nikhil I; Vassallo, Melinda; Goldberg, Judith D; Eroglu, Zeynep; Kim, Younchul; Cao, Biwei; Ferguson, Robert; Monson, Kelsey R; Kirchhoff, Tomas; Amato, Carol M; Burke, Paulo; Strange, Ann; Monk, Emily; Gibney, Geoffrey Thomas; Kudchadkar, Ragini; Markowitz, Joseph; Brohl, Andrew S; Pavlick, Anna; Richards, Alison; Woods, David M; Weber, Jeffrey

Journal for immunotherapy of cancer. 2022 Nov; 10(11):

Ascierto, Paolo A; Bifulco, Carlo; Ciardiello, Fortunato; Demaria, Sandra; Emens, Leisha A; Ferris, Robert; Formenti, Silvia C; Galon, Jerome; Khleif, Samir N; Kirchhoff, Tomas; McQuade, Jennifer; Odunsi, Kunle; Patnaik, Akash; Paulos, Chrystal M; Taube, Janis M; Timmerman, John; Fox, Bernard A; Hwu, Patrick; Puzanov, Igor

Journal of translational medicine. 2021 Jun 02; 19(1):238

Morales, Leah; Simpson, Danny; Ferguson, Robert; Cadley, John; Esteva, Eduardo; Monson, Kelsey; Chat, Vylyny; Martinez, Carlos; Weber, Jeffrey; Osman, Iman; Kirchhoff, Tomas

Journal of translational medicine. 2021 Feb 17; 19(1):78

Sayaman, Rosalyn W; Saad, Mohamad; Thorsson, Vésteinn; Hu, Donglei; Hendrickx, Wouter; Roelands, Jessica; Porta-Pardo, Eduard; Mokrab, Younes; Farshidfar, Farshad; Kirchhoff, Tomas; Sweis, Randy F; Bathe, Oliver F; Heimann, Carolina; Campbell, Michael J; Stretch, Cynthia; Huntsman, Scott; Graff, Rebecca E; Syed, Najeeb; Radvanyi, Laszlo; Shelley, Simon; Wolf, Denise; Marincola, Francesco M; Ceccarelli, Michele; Galon, Jérôme; Ziv, Elad; Bedognetti, Davide

Immunity. 2021 Feb 09; 54(2):367-386.e8