Perlmutter Cancer Center
Associate Professor, Department of Population Health
Associate Professor, Department of Environmental Medicine
The primary interest of my laboratory is focused on the identification of the genetic basis of cancer susceptibility. A key question in these efforts is how the germline genetic events contributing to predisposition of human cancers interact mutually in particular molecular pathways or in concert with the environmental exposures. Specifically, our ongoing studies aim at identification of the genetic variants conferring an increased risk to common cancers, such as breast, colon, prostate cancers or lymphoma, focusing on the relevant molecular pathways. These studies combine the genome-wide association analysis (GWAS), high-throughput genotyping and most recently the next-generation sequencing in large case/control populations. The significant aspect of my current and future research is an integration of the information from somatic genetics in tumors to complement the germline findings. We believe that such integration of biological data will be beneficial not only for improved prevention strategies but most importantly for the future development of the targeted personalized therapies.
212-263-9418
522 First Avenue
Twelfth Floor
New York, NY 10016
Associate Professor, Department of Population Health at NYU Grossman School of Medicine
Associate Professor, Department of Environmental Medicine at NYU Grossman School of Medicine
Memorial Sloan-Kettering Cancer Center, Clinical Cancer Genetics
Journal of translational medicine. 2021 Jun 02; 19(1):238
Journal of translational medicine. 2021 Feb 17; 19(1):78
Immunity. 2021 Feb 09; 54(2):367-386.e8
Journal of translational medicine. 2021 Jan 06; 19(1):13
Frontiers in genetics. 2021 Feb; 12:790445
Pigment cell & melanoma research. 2020 May; 33(3):466-479
Methods in molecular biology. 2020 Sep; 2055:93-117
Immuno-oncology technology. 2019 September; 2(pp):14-21