Tomas Kirchhoff, PhD

Perlmutter Cancer Center

Associate Professor, Department of Population Health

Associate Professor, Department of Environmental Medicine

Keywords
cancer, computational biology, epidemiology, genomics
Summary

The primary interest of my laboratory is focused on the identification of the genetic basis of cancer susceptibility. A key question in these efforts is how the germline genetic events contributing to predisposition of human cancers interact mutually in particular molecular pathways or in concert with the environmental exposures. Specifically, our ongoing studies aim at identification of the genetic variants conferring an increased risk to common cancers, such as breast, colon, prostate cancers or lymphoma, focusing on the relevant molecular pathways. These studies combine the genome-wide association analysis (GWAS), high-throughput genotyping and most recently the next-generation sequencing in large case/control populations. The significant aspect of my current and future research is an integration of the information from somatic genetics in tumors to complement the germline findings. We believe that such integration of biological data will be beneficial not only for improved prevention strategies but most importantly for the future development of the targeted personalized therapies.

Phone

212-263-9418

Academic office

522 First Avenue

Twelfth Floor

New York, NY 10016

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Associate Professor, Department of Population Health

Associate Professor, Department of Environmental Medicine

Ferguson, Robert; Vogelsang, Matjaz; Ucisik-Akkaya, Esma; Rai, Karan; Pilarski, Robert; Martinez, Carlos N; Rendleman, Justin; Kazlow, Esther; Nagdimov, Khagay; Osman, Iman; Klein, Robert J; Davidorf, Frederick H; Cebulla, Colleen M; Abdel-Rahman, Mohamed H; Kirchhoff, Tomas

Scientific reports. 2016 Aug 08; 6:31191-31191

Vogelsang, Matjaz; Martinez, Carlos N; Rendleman, Justin; Bapodra, Anuj Bapodra; Malecek, Karolina; Romanchuk, Artur; Kazlow, Esther; Shapiro, Richard L; Berman, Russell S; Krogsgaard, Michelle; Osman, Iman; Kirchhoff, Tomas

Clinical cancer research. 2016 Jul 01; 22(13):3268-3280

Pires Silva, Ines; Salhi, Amel; Giles, Keith M; Vogelsang, Matjaz; Han, Sung Won; Ismaili, Naima; Lui, Kevin P; Robinson, Eric M; Wilson, Melissa A; Shapiro, Richard L; Pavlick, Anna; Zhong, Judy; Kirchhoff, Tomas; Osman, Iman

Clinical cancer research. 2016 May 15; 22(10):2377-2385

Vogelsang, Matjaz; Wilson, Melissa; Kirchhoff, Tomas

Pigment cell & melanoma research. 2016 Jan; 29(1):15-26

Weiss, Sarah; Darvishian, Farbod; Tadepalli, Jyothi; Shapiro, Richard; Golfinos, John; Pavlick, Anna; Polsky, David; Kirchhoff, Tomas; Osman, Iman

BMC cancer. 2015 Nov 23; 15:926-926

Gumaste, P V; Penn, L A; Cymerman, R M; Kirchhoff, T; Polsky, D; McLellan, B

British journal of dermatology. 2015 Jun; 172(6):1498-1506

Tumor infiltrating lymphocyte (TIL) classifications and association with survival in primary melanomas. [Meeting Abstract]

Weiss, Sarah Ann; Han, Sung Won; Vogelsang, Matjaz; Krogsgaard, Michelle; Lui, Kevin P; Shapiro, Richard L; Kirchhoff, Tomas; Darvishian, Farbod; Osman, Iman

Journal of clinical oncology. 2015 MAY 20; 33(15):?-?

The expression quantitative trait loci (eQTLs) and their association with melanoma clinical outcomes [Meeting Abstract]

Vogelsang, Matjaz; Martinez, Carlos N; Romanchuk, Artur; Hecht, Chana; Richardson, Olivia; Shapiro, Richard L; Berman, Russell S; Osman, Iman; Kirchhoff, Tomas

Journal of clinical oncology. 2015 MAY 20; 33(15):?-?