Skip to Main Content

Weimin Zhang, PhD

Institute for Systems Genetics

Research Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Keywords
Synthetic genomes, Disease modeling in mouse, COVID-19, Cancer

Is this your profile?
Edit profile

Positions

Research Assistant Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Graduate Education

PhD from Tsinghua University

Genomic context sensitizes regulatory elements to genetic disruption

Ordoñez, Raquel; Zhang, Weimin; Ellis, Gwen; Zhu, Yinan; Ashe, Hannah J; Ribeiro-Dos-Santos, André M; Brosh, Ran; Huang, Emily; Hogan, Megan S; Boeke, Jef D; Maurano, Matthew T

bioRxiv : the preprint server for biology. 2024 Mar 12;

Large-scale genomic rearrangements boost SCRaMbLE in Saccharomyces cerevisiae

Cheng, Li; Zhao, Shijun; Li, Tianyi; Hou, Sha; Luo, Zhouqing; Xu, Jinsheng; Yu, Wenfei; Jiang, Shuangying; Monti, Marco; Schindler, Daniel; Zhang, Weimin; Hou, Chunhui; Ma, Yingxin; Cai, Yizhi; Boeke, Jef D; Dai, Junbiao

Nature communications. 2024 Jan 26; 15(1):770

Manipulating the 3D organization of the largest synthetic yeast chromosome

Zhang, Weimin; Lazar-Stefanita, Luciana; Yamashita, Hitoyoshi; Shen, Michael J; Mitchell, Leslie A; Kurasawa, Hikaru; Lobzaev, Evgenii; Fanfani, Viola; Haase, Max A B; Sun, Xiaoji; Jiang, Qingwen; Goldberg, Gregory W; Ichikawa, David M; Lauer, Stephanie L; McCulloch, Laura H; Easo, Nicole; Lin, S Jiaming; Camellato, Brendan R; Zhu, Yinan; Cai, Jitong; Xu, Zhuwei; Zhao, Yu; Sacasa, Maya; ,; Noyes, Marcus B; Bader, Joel S; Deutsch, Samuel; Stracquadanio, Giovanni; Aizawa, Yasunori; Dai, Junbiao; Boeke, Jef D

Molecular cell. 2023 Dec 07; 83(23):4424-4437.e5

Building a eukaryotic chromosome arm by de novo design and synthesis

Jiang, Shuangying; Luo, Zhouqing; Wu, Jie; Yu, Kang; Zhao, Shijun; Cai, Zelin; Yu, Wenfei; Wang, Hui; Cheng, Li; Liang, Zhenzhen; Gao, Hui; Monti, Marco; Schindler, Daniel; Huang, Linsen; Zeng, Cheng; Zhang, Weimin; Zhou, Chun; Tang, Yuanwei; Li, Tianyi; Ma, Yingxin; Cai, Yizhi; Boeke, Jef D; Zhao, Qiao; Dai, Junbiao

Nature communications. 2023 Nov 30; 14(1):7886

Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions

Zhao, Yu; Coelho, Camila; Hughes, Amanda L; Lazar-Stefanita, Luciana; Yang, Sandy; Brooks, Aaron N; Walker, Roy S K; Zhang, Weimin; Lauer, Stephanie; Hernandez, Cindy; Cai, Jitong; Mitchell, Leslie A; Agmon, Neta; Shen, Yue; Sall, Joseph; Fanfani, Viola; Jalan, Anavi; Rivera, Jordan; Liang, Feng-Xia; Bader, Joel S; Stracquadanio, Giovanni; Steinmetz, Lars M; Cai, Yizhi; Boeke, Jef D

Cell. 2023 Nov 22; 186(24):5220-5236.e16

Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains

McCulloch, Laura H; Sambasivam, Vijayan; Hughes, Amanda L; Annaluru, Narayana; Ramalingam, Sivaprakash; Fanfani, Viola; Lobzaev, Evgenii; Mitchell, Leslie A; Cai, Jitong; ,; Jiang, Hua; LaCava, John; Taylor, Martin S; Bishai, William R; Stracquadanio, Giovanni; Steinmetz, Lars M; Bader, Joel S; Zhang, Weimin; Boeke, Jef D; Chandrasegaran, Srinivasan

Cell genomics. 2023 Nov 08; 3(11):100419

Context-dependent neocentromere activity in synthetic yeast chromosome VIII

Lauer, Stephanie; Luo, Jingchuan; Lazar-Stefanita, Luciana; Zhang, Weimin; McCulloch, Laura H; Fanfani, Viola; Lobzaev, Evgenii; Haase, Max A B; Easo, Nicole; Zhao, Yu; Yu, Fangzhou; Cai, Jitong; ,; Bader, Joel S; Stracquadanio, Giovanni; Boeke, Jef D

Cell genomics. 2023 Nov 08; 3(11):100437

Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function

Luo, Jingchuan; Vale-Silva, Luis A; Raghavan, Adhithi R; Mercy, Guillaume; Heldrich, Jonna; Sun, Xiaoji; Li, Mingyu Kenneth; Zhang, Weimin; Agmon, Neta; Yang, Kun; Cai, Jitong; Stracquadanio, Giovanni; Thierry, Agnès; Zhao, Yu; Coelho, Camila; McCulloch, Laura H; Lauer, Stephanie; ,; Kaback, David B; Bader, Joel S; Mitchell, Leslie A; Mozziconacci, Julien; Koszul, Romain; Hochwagen, Andreas; Boeke, Jef D

Cell genomics. 2023 Nov 08; 3(11):100439

See All Publications (20)

Read Story
Read Story
Read Story