William J. Rice, PhD

Assistant Professor, Department of Cell Biology

Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Positions

Assistant Professor, Department of Cell Biology at NYU Grossman School of Medicine

Assistant Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Core Director, Cryo-Electron Microscopy Laboratory (Cryo-EM)

Graduate Education

PhD from University of Toronto

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BRAF oncogenic mutants evade autoinhibition through a common mechanism

Lavoie, Hugo; Jin, Ting; Lajoie, Driss; Decossas, Marion; Gendron, Patrick; Wang, Bing; Filandr, Frantisek; Sahmi, Malha; Hwa Jo, Chang; Weber, Sandra; Arseneault, Geneviève; Tripathy, Sasmita; Beaulieu, Pierre; Schuetz, Doris A; Schriemer, David C; Marinier, Anne; Rice, William J; Maisonneuve, Pierre; Therrien, Marc

Science (New York, N.Y.). 2025 May 29; 388(6750):eadp2742

Substrate translocation and inhibition in human dicarboxylate transporter NaDC3

Li, Yan; Song, Jinmei; Mikusevic, Vedrana; Marden, Jennifer J; Becerril, Alissa; Kuang, Huihui; Wang, Bing; Rice, William J; Mindell, Joseph A; Wang, Da-Neng

Nature structural & molecular biology. 2025 Mar; 32(3):502-512

Structural insights into the diversity and DNA cleavage mechanism of Fanzor

Xu, Peiyu; Saito, Makoto; Faure, Guilhem; Maguire, Samantha; Chau-Duy-Tam Vo, Samuel; Wilkinson, Max E; Kuang, Huihui; Wang, Bing; Rice, William J; Macrae, Rhiannon K; Zhang, Feng

Cell. 2024 Sep 19; 187(19):5238-5252.e20

Applying 3D ED/MicroED workflows toward the next frontiers

Aragon, Mahira; Bowman, Sarah E J; Chen, Chun Hsing; de la Cruz, M Jason; Decato, Daniel A; Eng, Edward T; Flatt, Kristen M; Gulati, Sahil; Li, Yuchen; Lomba, Charles J; Mercado, Brandon; Miller, Jessalyn; Palatinus, Lukáš; Rice, William J; Waterman, David; Zimanyi, Christina M

Acta crystallographica. Section C, Structural chemistry. 2024 Jun 01; 80(Pt 6):179-189

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1

Thomas, Jonathan F; Valencia-Sánchez, Marco Igor; Tamburri, Simone; Gloor, Susan L; Rustichelli, Samantha; Godínez-López, Victoria; De Ioannes, Pablo; Lee, Rachel; Abini-Agbomson, Stephen; Gretarsson, Kristjan; Burg, Jonathan M; Hickman, Allison R; Sun, Lu; Gopinath, Saarang; Taylor, Hailey F; Sun, Zu-Wen; Ezell, Ryan J; Vaidya, Anup; Meiners, Matthew J; Cheek, Marcus A; Rice, William J; Svetlov, Vladimir; Nudler, Evgeny; Lu, Chao; Keogh, Michael-Christopher; Pasini, Diego; Armache, Karim-Jean

Science advances. 2023 Aug 09; 9(32):eadg9832

Measuring the Effect of Ice Thickness and Microscope Configuration on Resolution in Single Particle Cryo-EM

Chua, Eugene Y D; Neselu, Kasahun; Wang, Bing; Rice, William J; Potter, Clinton S; Carragher, Bridget

Microscopy & microanalysis. 2023 Jul 22; 29(29 Suppl 1):1040

CD19 CAR antigen engagement mechanisms and affinity tuning

He, Changhao; Mansilla-Soto, Jorge; Khanra, Nandish; Hamieh, Mohamad; Bustos, Victor; Paquette, Alice J; Garcia Angus, Andreina; Shore, Derek M; Rice, William J; Khelashvili, George; Sadelain, Michel; Meyerson, Joel R

Science immunology. 2023 Mar 10; 8(81):eadf1426

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1

Thomas, Jonathan F; Valencia-Sánchez, Marco Igor; Tamburri, Simone; Gloor, Susan L; Rustichelli, Samantha; Godínez-López, Victoria; De Ioannes, Pablo; Lee, Rachel; Abini-Agbomson, Stephen; Gretarsson, Kristjan; Burg, Jonathan M; Hickman, Allison R; Sun, Lu; Gopinath, Saarang; Taylor, Hailey; Meiners, Matthew J; Cheek, Marcus A; Rice, William; Nudler, Evgeny; Lu, Chao; Keogh, Michael-Christopher; Pasini, Diego; Armache, Karim-Jean

bioRxiv.org : the preprint server for biology. 2023 Feb 23;

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