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Xin Li

Associate Professor, Department of Urology

Keywords
prostate cancer, bone metabolism, diabetes
Summary

The research projects in our laboratory are centered on the mechanisms of action of metformin, the most prescribed anti–type II diabetes medicine. We are particularly interested in its antineoplastic effects and its impact on bone metabolism in diabetes.

Using various animal and cell culture models and molecular and cellular techniques, we have revealed the role of metformin as an epigenetic regulator and metabolic rebalancer, restoring normal cellular function in cancer and diabetes.

Phone

212-992-7009

Fax

212-995-4085

Academic office

345 East 24th Street, 901D

New York, NY 10010

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These focus areas and their associated publications are derived from medical subject headings from PubMed.
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*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

Positions

Associate Professor, Department of Urology at NYU Grossman School of Medicine

Postdoctoral Training

University of Michigan, Laurie McCauley

A novel SUCNR1 inhibitor alleviates dysbiosis through inhibition of host responses without direct interaction with host microbiota

Thomas, Scott C; Guo, Yuqi; Xu, Fangxi; Saxena, Deepak; Li, Xin

Molecular oral microbiology. 2023 Sep 16;

Metformin regulates bone marrow stromal cells to accelerate bone healing in diabetic mice

Guo, Yuqi; Wei, Jianlu; Liu, Chuanju; Li, Xin; Yan, Wenbo

eLife. 2023 Jul 07; 12:

Risk factors associated with low bone mineral density in children with idiopathic scoliosis: a scoping review

Yang, Yuqi; Chen, Zhengquan; Huang, Zefan; Tao, Jing; Li, Xin; Zhou, Xuan; Du, Qing

BMC musculoskeletal disorders. 2023 Jan 20; 24(1):48

Bone mineral density in children and young adults with idiopathic scoliosis: a systematic review and meta-analysis

Yang, Yuqi; Han, Xiaoli; Chen, Zhengquan; Li, Xin; Zhu, Xiaoqing; Yuan, Haiyan; Huang, Zefan; Zhou, Xuan; Du, Qing

European spine journal. 2023 Jan; 32(1):149-166

The tumor mycobiome: A paradigm shift in cancer pathogenesis

Li, Xin; Saxena, Deepak

Cell. 2022 Sep 29; 185(20):3648-3651

Targeting the succinate receptor effectively inhibits periodontitis

Guo, Yuqi; Xu, Fangxi; Thomas, Scott C; Zhang, Yanli; Paul, Bidisha; Sakilam, Satish; Chae, Sungpil; Li, Patty; Almeter, Caleb; Kamer, Angela R; Arora, Paramjit; Graves, Dana T; Saxena, Deepak; Li, Xin

Cell reports. 2022 Sep 20; 40(12):111389

Neuroinflammation: A Distal Consequence of Periodontitis

Li, X; Kiprowska, M; Kansara, T; Kansara, P; Li, P

Journal of dental research. 2022 Jun 16; 220345221102084

Intrahepatic microbes govern liver immunity by programming NKT cells

Leinwand, Joshua C; Paul, Bidisha; Chen, Ruonan; Xu, Fangxi; Sierra, Maria A; Paluru, Madan M; Nanduri, Sumant; Alcantara Hirsch, Carolina G; Shadaloey, Sorin Aa; Yang, Fan; Adam, Salma A; Li, Qianhao; Bandel, Michelle; Gakhal, Inderdeep; Appiah, Lara; Guo, Yuqi; Vardhan, Mridula; Flaminio, Zia J; Grodman, Emilie R; Mermelstein, Ari; Wang, Wei; Diskin, Brian; Aykut, Berk; Khan, Mohammed; Werba, Gregor; Pushalkar, Smruti; McKinstry, Mia; Kluger, Zachary; Park, Jaimie J; Hsieh, Brandon; Dancel-Manning, Kristen; Liang, Feng-Xia; Park, James S; Saxena, Anjana; Li, Xin; Theise, Neil D; Saxena, Deepak; Miller, George

Journal of clinical investigation. 2022 Apr 15; 132(8):

See All Publications (99)