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Zhe S. Chen

Zhe S. Chen, PhD

Associate Professor, Department of Psychiatry

Associate Professor, Department of Neuroscience and Physiology

integration of computational and experimental techniques to dissect neural circuits and neural population codes, computational neuroscience, neural engineering, computational statistics, machine learning, computational psychiatry, behavior modeling

Our current research focuses on combining multidisciplinary techniques: electrophysiology, computational modeling of circuits and behavior,  statistical analysis of neural data, and neural engineering to investigate basic and translational neuroscience questions, and to address challenging data analytic problems in neuropsychiatric clinical research.

In collaboration with experimental neuroscientists, we are working on several exciting projects: learning and memory associated with hippocampal-cortical circuits; thalamocortical and cortico-thalamic circuits in working memory and executive control; and, real-time brain-machine interface for pain circuits and memory circuits.



Academic office

One Park Avenue

Eighth Floor, Rm 226

New York, NY 10016

Lab Website
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These focus areas and their associated publications are derived from medical subject headings from PubMed.
represents one publication
*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

PhD from McMaster University

Harvard Medical School, Neuroscience Statistics Research Lab

Friesner, Isabel D; Martinez, Erik; Zhou, Haocheng; Gould, Jonathan Douglas; Li, Anna; Chen, Zhe Sage; Zhang, Qiaosheng; Wang, Jing

Molecular brain. 2020 Sep 23; 13(1):129

Rajakumar, Alfred; Rinzel, John; Chen, Zhe S

Neural computation. 2021 Sep 16; 33(10):2603-2645

Bhattacharya, Sayak; Cauchois, Matthieu B L; Iglesias, Pablo A; Chen, Zhe Sage

Scientific reports. 2021 Jul 13; 11(1):14359

Zhang, Qiaosheng; Hu, Sile; Talay, Robert; Xiao, Zhengdong; Rosenberg, David; Liu, Yaling; Sun, Guanghao; Li, Anna; Caravan, Bassir; Singh, Amrita; Gould, Jonathan D; Chen, Zhe S; Wang, Jing

Nature biomedical engineering. 2021 Jun 21;

Wen, Zhenfu; Chen, Zhe Sage; Milad, Mohammed R

Neuroimage. 2021 Jun 11; 118261

Chen, Zhe Sage; Pesaran, Bijan

Neuron. 2021 Jun 02; 109(11):1776-1790

Song, Yuru; Yao, Mingchen; Kemprecos, Helen; Byrne, Aine; Xiao, Zhengdong; Zhang, Qiaosheng; Singh, Amrita; Wang, Jing; Chen, Zhe S

Journal of computational neuroscience. 2021 May; 49:107-127