Zhe S. Chen

Zhe S. Chen, PhD

Associate Professor, Department of Psychiatry

Associate Professor, Department of Neuroscience and Physiology

Keywords
integration of computational and experimental techniques to dissect neural circuits and neural population codes, computational neuroscience, neural engineering, computational statistics, machine learning, computational psychiatry, behavior modeling
Summary

Our current research focuses on combining multidisciplinary techniques: electrophysiology, computational modeling of circuits and behavior,  statistical analysis of neural data, and neural engineering to investigate basic and translational neuroscience questions, and to address challenging data analytic problems in neuropsychiatric clinical research.

In collaboration with experimental neuroscientists, we are working on several exciting projects: learning and memory associated with hippocampal-cortical circuits; thalamocortical and cortico-thalamic circuits in working memory and executive control; and, real-time brain-machine interface for pain circuits and memory circuits.

Phone

646-754-4765

Academic office

One Park Avenue

Eighth Floor, Rm 226

New York, NY 10016

Lab Website
Chen Laboratory
Is this your profile?
Edit profile

Positions

Associate Professor, Department of Psychiatry at NYU Grossman School of Medicine

Associate Professor, Department of Neuroscience and Physiology at NYU Grossman School of Medicine

Director, Computational Psychiatry Research Program

Graduate Education

PhD from McMaster University

Postdoctoral Training

Harvard Medical School, Neuroscience Statistics Research Lab

Uncovering spatial representations from spatiotemporal patterns of rodent hippocampal field potentials

Cao, Liang; Varga, Viktor; Chen, Zhe S

Cell reports methods. 2021 Nov 22; 1(7):

Decoding pain from brain activity

Chen, Zhe Sage

Journal of neural engineering. 2021 Oct 04; 18(5):

Sharp Tuning of Head Direction and Angular Head Velocity Cells in the Somatosensory Cortex

Long, Xiaoyang; Deng, Bin; Young, Calvin K; Liu, Guo-Long; Zhong, Zeqi; Chen, Qian; Yang, Hui; Lv, Sheng-Qing; Chen, Zhe Sage; Zhang, Sheng-Jia

Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2022 Mar 17; e2200020

Mediodorsal thalamus regulates task uncertainty to enable cognitive flexibility

Zhang, Xiaohan; Mukherjee, Arghya; Halassa, Michael M; Chen, Zhe Sage

Nature communications. 2025 Mar 18; 16(1):2640

Inferring directed spectral information flow between mixed-frequency time series

Xian, Qiqi; Chen, Zhe Sage

Research square. 2025 Feb 28;

Prefrontal transthalamic uncertainty processing drives flexible switching

Lam, Norman H; Mukherjee, Arghya; Wimmer, Ralf D; Nassar, Matthew R; Chen, Zhe Sage; Halassa, Michael M

Nature. 2025 Jan; 637(8044):127-136

Closed-loop neural interfaces for pain: Where do we stand?

Wang, Jing; Chen, Zhe Sage

Cell reports. Medicine. 2024 Oct 15; 5(10):101662

Identifying behavioral links to neural dynamics of multifiber photometry recordings in a mouse social behavior network

Chen, Yibo; Chien, Jonathan; Dai, Bing; Lin, Dayu; Chen, Zhe Sage

Journal of neural engineering. 2024 Jun 25; 21(3):

See All Publications (131)