Kirsch Lab

The Kirsch Laboratory studies novel mechanisms involved in the regulation of cartilage homeostasis, maintenance and pathology with the ultimate goal to define novel therapeutic targets for the treatment of osteoarthritis. In addition, the laboratory is interested in how cells and the environment in the joint communicate to maintain organ health and how such communication networks are altered in joint diseases or injuries.

The Kirsch Laboratory is located in the Bioengineering Institute at 433 First Avenue in Manhattan. The modern laboratory space in the Bioengineering Institute is being shared between the Department of Orthopaedic Surgery at NYU School of Medicine and the Department of Biomedical Engineering at NYU Tandon School of Engineering to foster a collaborative environment for the discovery of novel therapeutic strategies for musculoskeletal tissue repair and regeneration.

The Broad Research Focus Areas in the Kirsch Laboratory

  • Cartilage and bone biology
  • Musculoskeletal tissue injury, repair and regeneration
  • Matrix biology
  • Biology of extracellular vesicles in health and disease
  • Osteoarthritis