Associate Professor, Department of Neuroscience & Physiology
NYU Neuroscience Institute
Our lab is using electrophysiology, imaging, optogenetics, and psychophysics to understand the principles of the sensory information processing. Specifically we are focused on two questions: 1) how is odor information represented in the brain of the awake, behaving mouse? & 2) how is the information that is relevant to animal behavior extracted by the brain? In short, we want to understand what the mouse’s nose tells its brain.
Recently, our laboratory has been focused on temporal aspects of olfactory coding. Contrary to the common belief, we demonstrated that olfactory processing is temporally very precise at both the levels of the neural code (Shusterman-2011) and of behavior (Smear-2011, -2013), and also that it can be very fast: mice can make olfactory decisions in less than 100 ms (Resulaj-2015).
Our current efforts are directed towards establishing causal connection between neuronal coding and animal behavior.
Smear, M., A. Resulaj, J. Zhang, T. Bozza, and D. Rinberg. Multiple perceptible signals from a single olfactory glomerulus. Nature Neuroscience 16, pp.1687–1691 (2013).
Smear, M., Shusterman, R., O’Connor, R., Bozza, T. & Rinberg, D. Perception of sniff phase in mouse olfaction. Nature 479, 397–400 (2011).
Shusterman, R., Smear, M. C., Koulakov, A. A. & Rinberg, D. Precise olfactory responses tile the sniff cycle. Nat Neurosci 14, 1039–1044 (2011).
Koulakov, A. A. & Rinberg, D. Sparse Incomplete Representations: A Potential Role of Olfactory Granule Cells. Neuron 72, 124–136 (2011).
Rinberg, D., Koulakov, A. & Gelperin, A. Speed-accuracy tradeoff in olfaction. Neuron 51, 351–358 (2006).