WUH: Impact of medical and surgical weight loss on lipocalin prostaglandin D2 synthase (LPGDS) and bile acid levels.
Obesity and type 2 diabetes are medical conditions that are associated with significant health risks. These include stroke, heart disease, and kidney disease. Medical research has been attempting to identify new ways to treat both of these diseases. What clinicians have recently noticed, is the impact of a low calorie diet and weight loss surgery appears to have a profound beneficial role on both obesity and type 2 diabetes. However, the mechanism of how this is achieved remains unclear. This study will attempt to study various proteins and hormone levels that may become altered with dietary restriction and weight loss surgery. Specifically, the research laboratory has studied and identified a protein known as “Lipocalin Prostaglandin D2 Synthase.” It appears to be associated with both obesity and type 2 diabetes. This protein and various others will be examined to better understand their biologic roles.
WUH: NATURAL HISTORY STUDY OF THE DEVELOPMENT OF TYPE 1 DIABETES
An important part of this study is to better understand what causes type 1 diabetes, to look for new ways to identify people at risk for disease, and to get ideas about new treatments in the future. While TrialNet is ongoing, participant's blood samples will be and used only by TrialNet approved researchers. You will not routinely be provided with test results from these studies. The study is divided into two phases: Screening and Monitoring. The screening phase of the study will include testing for diabetes related auto antibodies in the blood. The Monitoring Phase will require that completing several tests. An important part of this study is to better understand what causes type 1 diabetes, to look for new ways to identify people at risk for disease, and to get ideas about new treatments in the future.
X-Ray Imaging | NYU Langone Health
NYU Langone offers bone, chest, abdominal, and dental X-rays.
Young Lung Cancer Program | NYU Langone Health
Experts at the Young Lung Cancer Program, part of NYU Langone’s Lung Cancer Center, offer personalized care for younger people with lung cancer.
Young Onset Parkinson's disease Subtypes and Pathogenic Mechanisms (YOPD Study)
Young Onset Parkinson's disease (YOPD) occurs in patients before the age of 50 years. Our current knowledge about the mechanisms that cause YOPD is lacking. Understanding these causes is crucial for the successful design of therapeutic strategies and clinical trials. We know that different factors contribute to cause Parkinson’s disease, including the buildup of a protein (alpha-synuclein) in different areas of the brain, inflammation, and genetics. The clinical presentation, progression, and severity of the symptoms can be different across subjects with YOPD. These differences may be due to different underlying mechanisms or due to a combination of different factors described before (protein accumulation, inflammation and genetics). The purpose of this study will be to collect clinical and genetic information as well as to characterize the inflammation and alpha-synuclein aggregation profiles in a large group of subjects with YOPD in order to define disease clinical and mechanistic subtypes. The identification of different YOPD sub-types from a clinical as well as a mechanistic point of view (including different disease rate of progression of the symptoms, genetic mutations and biomarker profiles) is crucial to better inform patients about possible disease outcomes and implications for them and their family members in addition for the designing of therapeutic approaches that may be able to delay or stop disease progression.
Your Cancer Care Team | NYU Langone Health
At Perlmutter Cancer Center, your cancer care team works together to provide individualized diagnostic testing and treatment.
Your Child’s Care Team | NYU Langone Health
Meet the members of the care team at Hassenfeld Children’s Hospital at NYU Langone.
Your Child's ECMO Treatment | NYU Langone Health
At Hassenfeld Children’s Hospital at NYU Langone, we provide support while your child is receiving extracorporeal membrane oxygenation (ECMO).
Your Child’s Visit | NYU Langone Health
We help you prepare for your child’s visit to Hassenfeld Children’s Hospital at NYU Langone.
Your Emergency Care Visit | NYU Langone Health
NYU Langone offers information about what to expect during your emergency care visit in Manhattan, Brooklyn, or Long Island.
