Adult ECMO Program Doctors | NYU Langone Health
Find a doctor at the Adult ECMO Program at NYU Langone.
Adult Inpatient Rehabilitation Services | NYU Langone Health
The team at NYU Langone’s Rusk Rehabilitation provides inpatient rehabilitation care for people recovering from severe illness and injury.
Adult Medicine Program—Family Health Centers at NYU Langone | NYU Langone Health
The Adult Medicine Program—Family Health Centers at NYU Langone provides annual checkups, screenings, and specialized care for men and women.
Adult Reconstructive Surgery | NYU Langone Health
Our adult reconstructive surgeons at NYU Langone perform more than 3,000 joint replacement procedures per year.
Adult Recreation & Creative Arts Therapies | NYU Langone Health
Using leisure, music, and art, the adult recreation and creative arts therapists at NYU Langone help you cope with your medical experience.
Adult Rehabilitation Services | NYU Langone Health
At NYU Langone’s Rusk Rehabilitation, we provide rehabilitation care for adults who have experienced illness or injury.
Advance Care Planning | NYU Langone Health
Advance care planning and completion of an advance directive are part of the patient experience at NYU Langone.
ADVANCED DIFFUSION IMAGING IN RENAL TISSUE: TECHNICAL OPTIMIZATION
The objective of this study is to optimize imaging protocols and analysis for advanced diffusion-weighted MRI of the kidney. We hypothesize that this optimization will produce a robust and reproducible workflow with minimal variance for application in future renal function clinical studies
Advanced Imaging Characteristics Following Nerve Repair in the Early and Midterm Postoperative Period Predictive of Functional Outcome
The purpose of this study is to determine the efficacy of ultrasound and magnetic resonance imaging (MRI) in characterizing the healing process across a coaptation after nerve repair surgery and determine how imaging findings correlate to clinical outcome. This project would be a feasibility study where several patients will be recruited to receive an MRI and ultrasound at several predetermined time points after nerve repair surgery to allow for the characterization of imaging findings that are useful and predictive for evaluating the healing process. This information will result in improved patient education and expedited intervention based on prognosis, with the ultimate goal of improving patient outcomes.
AERODIGESTIVE DISEASE IN THE WORLD TRADE CENTER EXPOSED FDNY COHORT: A Single Center Observational Study of Biomarkers of Airway Disease Barrett s and Underdiagnosed Reflux Noninvasively
The destruction of the World Trade Center (WTC) led to the exposure of thousands of first responders and inhabitants of New York City to WTC-particulate matter (WTC-PM). WTC-PM exposure in our Fire Department of New York (FDNY) cohort is associated with the development of obstructive airways disease (OAD), gastroesophageal reflux disease (GERD) and Barrett’s Esophagus (BE). GERD is a well-known risk factor of the metaplastic changes of BE, which can subsequently lead to adenocarcinoma. GERD is also associated with occupational or environmental exposure related OAD. Overall, WTC-exposed firefighters with OAD had a three times higher risk of developing GERD. At least 40% of WTC rescue and recovery workers have developed GERD symptoms, which is 8.2 times its pre-9/11 prevalence. It is in the context of these findings that we propose to study Aerodigestive Disease in the World Trade Center Exposed FDNY Cohort: Validation of Biomarkers and Defining Risk to Tailor Therapy. Research that will further define, phenotype aerodigestive/gastrointestinal health biomarkers, determine impact on lung health to improve care fulfill the mandate of the James Zadroga 9/11 Health and Compensation Act and are in line with PAR-16-098.GERD diminishes health-related quality of life and productivity. Complications of GERD can further extend beyond BE; extra-esophageal reflux can incite or exacerbate allergies, sinusitis, chronic bronchitis, and asthma. Management of reflux is challenging and often refractory to proton pump inhibitor (PPI) therapy, with associated significant health costs. WTC-PM exposure associated asthma more often had, persistent GERD. Although many studies have suggested interdependence between airway and digestive diseases, the causative factors and specific mechanisms remain unclear. There is no gold standard of GERD diagnosis and few disease specific biomarkers. We have successfully identified metabolic, vascular and inflammatory biomarkers of WTC-airway hyperreactivity (WTC-AHR). We have identify biomarkers of GERD/BE in our WTC exposed population with respiratory disease, facilitating identification of biologically relevant immune pathways. In addition, we now present data that GERD increases the odds of developing WTC-AHR, independent of exposure intensity. We propose 2 AIMs to explore the HYPOTHESIS that serum biomarkers will be different in FDNY rescue and recovery workers who proceed to develop GERD/BE. Noninvasive biomarkers will identify subjects that may require improved treatment. We are requesting funding of our translational research to leverage the longitudinally phenotyped FDNY-WTC cohort and identify Biomarkers of Airway Disease, Barrett’s and Underdiagnosed Reflux Noninvasively (BAD-BURN). We will validate biomarkers of GERD and BE (AIM 1), and phenotype subgroups with aerodigestive disease to identify noninvasive biomarkers of under-diagnosis/treatment efficacy to inform future biologically plausible therapies to improve care (AIM 2).