Deep learning on ECGs to improve outcomes in patients on dialysis
During hemodialysis, a rapid fluid removal can cause fall in blood pressure. When compensatorymechanisms fail to raise blood pressure, chronic kidney disease patients can suffer from intradialytic(meaning something that happens during dialysis) hypotension (IDH) that requires immediateintervention to prevent syncope and vital organs blood supply interruption. IDH is a frequent and seriouscomplication of chronic hemodialysis, linked to adverse long-term outcomes including increasedcardiovascular and all-cause mortality.The purpose of this research study is to use machine learning and ECGs obtained at hemodialysistreatment start to predict intradialytic hypotension during hemodialysis treatment and over the following30 days with the purpose of improving the prediction and management of intradialytic hypotension andmajor adverse cardiac events in end-stage kidney disease patients receiving maintenancehemodialysis.
Deep Vein Thrombosis | NYU Langone Health
NYU Langone specialists recognize and quickly manage deep vein thrombosis, sometimes called DVT, before serious complications develop.
Defining the Impact of Peyronie s Disease on Sexual Quality of Life for Partners
In this study we will interview female partners of patients with Peyronie's disease about the impact of the disease on their sexual quality of life. We will use these data to develop a new instrument to evaluate self-reported sexual quality of life among partners of patients with Peyronie's disease.
Degenerative Disc Disease | NYU Langone Health
NYU Langone physicians and surgeons offer individualized care and support for people with degenerative disc disease.
Dementia | NYU Langone Health
NYU Langone offers evaluation, treatment, and rehabilitation services for all types of dementia.
Dental Medicine—Family Health Centers at NYU Langone | NYU Langone Health
Dental Medicine—Family Health Centers at NYU Langone provides dental care to adults, children, and people with special needs.
Dental Medicine—Family Health Centers at NYU Langone Doctors | NYU Langone Health
Find a doctor at Dental Medicine—Family Health Centers at NYU Langone.
Department Chairs | NYU Langone Health
The leadership of NYU Langone Health includes our renowned department chairs, each one an exemplary in their field.
Depression | NYU Langone Health
NYU Langone mental health specialists diagnose and manage depression.
Depression treatment and A dynamics: A study of Alzheimer s disease risk (ABD Study)
The study will use a randomized 8-week double-blind placebo controlled parallel trial using escitalopram to test the associations between depressive symptoms (captured by the MADRS and other depression scales), and AD biomarkers in both CSF and plasma as well as changes in vascular dysfunction (VD)-associated biomarkers(MMP2, MMP9, homocysteine, and platelet activation markers P-selectin and GP IIa/IIIb). The primary endpoints are the severity of depression symptoms at baseline, the change in depression scores after treatment with escitalopram, and the associated changes in AD and VD markers peptide levels. Secondary endpoints are depression severity at baseline, which will be tested in regression models in relation to the AD biomarkers (Aß peptides in CSF) cross-sectionally at baseline and after antidepressant treatment to test that Aß peptides are correlated with symptoms. The study will also examine if decreased levels of VD-associated biomarkers will (at least partially) mediate the effect of depression treatment response on increases in CSF Aß levels. This proposal will be the first to explore the relationships between CSF AD and VD biomarker levels and MDD symptom severity in cognitively normal MDD patients and the direction of causation between changes in Aß and VD biomarkers and changes in MDD symptom severity. The results of this study, if successful, may provide a rationale for reducing AD risk through a more effective treatment of depression in the elderly.