Study of inherited monogenic disorders in patient and tissue-specific cells
We propose to collect blood samples to reprogram into patient-specific neuronal, cardiac, and cancer cell lines (see below in the background section) from patients diagnosed with inherited epilepsy & neurodevelopmental disorders (NDDs) and arrhythmias & neuromuscular disorders (NMDs).
Study of newly identified natriuretic protein haptoglobin related protein without signal peptide as biomarker for renal salt wasting and new syndrome of renal salt wasting in Alzheimer s disease: Study to identify protein that alters brain cell function in Alzheimer s disease
This study is being done to better understand hyponatremia (low blood sodium). We have now identified a protein that may be used to diagnose a cause of hyponatremia, cerebral/renal salt wasting (C/RSW). C/RSW is the loss of excessive amounts of salt and water in the urine and is what causes dehydration or too little salt and water in your body. The dehydration can be severe enough to cause low blood pressure, weakness, loss of appetite, dizziness, confusion, trouble walking and even fainting, especially when you stand up. We have also identified that the same protein is present in the blood of subjects with C/RSW and with Alzheimer’s disease (AD). We have also shown that the brain cells of subjects with Alzheimer’s disease are altered. The major aims of this study are to: Develop the protein to help diagnose C/RSW. Use the protein to identify a new syndrome of C/RSW in subjects with Alzheimer’s disease and Identify the protein in the blood of subjects with Alzheimer’s disease that causes their brains cell to alter their function. We can then inhibit the function of this protein to possibly prevent the dementia of Alzheimer disease.
Stye | NYU Langone Health
NYU Langone ophthalmologists manage eyelid styes with simple home remedies, medication, or surgery.
Suffolk County & East End Locations | NYU Langone Health
See all NYU Langone locations in Suffolk County and East End, Long Island, and find locations in your neighborhood.
Sun Avoidance for Cutaneous Lupus | NYU Langone Health
NYU Langone dermatologists recommend limiting exposure to sunlight to manage the symptoms of cutaneous lupus.
Sun Protection for Dermatomyositis | NYU Langone Health
Doctors at NYU Langone recommend avoiding exposure to sunlight to prevent the skin rash associated with dermatomyositis.
SUNRAY-01 A Global Pivotal Study in Participants with KRAS G12C-Mutant Locally Advanced or Metastatic Non-Small Cell Lung Cancer Comparing FirstLine Treatment of LY3537982 and Pembrolizumab vs Placebo and Pembrolizumab in those with PD-L1 expression =50% or LY3537982 and Pembrolizumab Pemetrexed Platinum vs Placebo and Pembrolizumab Pemetrexed Platinum regardless of PD-L1 Expression
This study is testing two different treatments (LY3537982 in combination with pembrolizumab against a placebo combined with pembrolizumab) for a cancer called KRAS G12C-mutant NSCLC (non-small cell lung cancer). The study has two parts: Part A compares the treatments with one another for patients whose cancer has a marker called PD-L1 at a level of 50% or higher. Part B looks at the same treatments for patients with PD-L1 ranging from 0 to 100%. The decision about which part a patient joins depends on their doctor and what's best for treatment. Before joining, some patients might get one cycle of regular treatment if they really need it. The study also has two different doses of LY3537982 in combination with pembrolizumab, and they're trying to figure out the best amount, comparing different options to see which one works better. Overall, the study team is hoping to find better treatments for this type of lung cancer.
Sunset Park Family Health Center at NYU Langone—55th Street | NYU Langone Health
Experts at Sunset Park Family Health Center at NYU Langone—55th Street provide adult primary and specialty healthcare.
Sunset Park Family Health Center at NYU Langone—55th Street Doctors | NYU Langone Health
Find a doctor at Sunset Park Family Health Center at NYU Langone—55th Street.
Sunset Park Family Health Center at NYU Langone—Second Avenue | NYU Langone Health
Experts at Sunset Park Family Health Center at NYU Langone—Second Avenue provide healthcare services to women and children.