Rusk Rehabilitation | NYU Langone Health
At NYU Langone’s Rusk Rehabilitation, you receive care that meets your physical, social, emotional, cognitive, and psychological needs.
Elucidating Neural Mechanisms and Sex Differences in Response to Mindfulness Based Stress Reduction in Generalized Anxiety Disorder
Mindfulness-Based Stress Reduction (MBSR) has demonstrated efficacy for Generalized Anxiety Disorder (GAD), yet there remains a major knowledge gap about its neural mechanisms. Neuroimaging studies thus far have mostly focused on the impact of MBSR on structural and resting-state brain changes, and these studies have been predominantly conducted in healthy participants. Core features of GAD, such as ruminative worry, represent dysfunctional emotion regulation strategies that increase bias towards future threat. MBSR success is associated with improved emotion regulation, enhanced attention to the present moment, and non-judgmental acceptance of internal and external cues. Our primary aim is to elucidate neural mechanisms that drive response to MBSR in patients with generalized anxiety disorder (GAD), and to examine the degree to which sex differences in MBSR response are explained by sex differences in these mechanisms. Our overarching hypothesis is that MBSR enhances ‘top-down’ learning and memory capacities that are broad and impact ‘top-down’ as well as ‘instinctual’ abilities (bottom-up) to regulate fear and emotions. We will first study the functional activation of brain regions associated with the fear extinction network (ventromedial prefrontal cortex (vmPFC), hippocampus, and amygdala) as a specific probe of the ‘instinctual’ type of emotion regulation. Second, we will use a novel analytic approach to examine large-scale functional connectivity as a marker of neural plasticity changes (pre- and post-MBSR) trial-by-trial during fear extinction learning across the entire brain, focusing analyses on the default mode network (DMN), frontoparietal network (FPN), and ventral attention network (VAN). Next, we will examine sex differences in MBSR-induced neural changes and their relationship to sex differences in clinical GAD response. Finally, we will use a novel statistical approach to explore whether baseline neural measures can predict MBSR-induced neural changes and clinical symptom reduction to identify likely MBSR responders. Participants will undergo a standardized 2-day fear conditioning and extinction paradigm in the fMRI scanner before and after MBSR or stress education (SE) with primary clinical outcomes at endpoint and 3 month follow-up. This study will deploy rigorous scientific methods with a time and attention control intervention to enable isolation of MBSR’s mechanistic impact on brain regions involved in emotion regulation and clinical response. The unique combination of a focus on a classic anxiety condition with established emotion regulation difficulties implicating target neural circuits, previously demonstrated MBSR efficacy, and sex differences with rigorous fMRI behavioral probes with novel analytic approaches ought to provide major new insights about MBSR mechanisms and sex considerations, moving towards precision medicine that could guide future treatment development research.
Our Dance Medicine Team | NYU Langone Health
Experts at NYU Langone’s Harkness Center for Dance Injuries aim to improve the delivery of dance medicine.
Voice, Swallowing & Airway Conditions We Treat | NYU Langone Health
At NYU Langone’s Voice Center, we are experts in a range of conditions that affect your ability to speak, swallow, and breathe.
chnaa-csp.pdf
... , Nassau and Suffolk Counties Table of Contents SECTION PAGES MISSION 1 OVERVIEW 2-7 PRIORITY AREAS ... OF FOCUS I. COMMUNITY HEALTH NEEDS AND ASSETS ASSESSMENT 7-38 A. Definition and Brief Description ...
fhc-heia-relocation-and-consolidation-heia.pdf
... and clinical advisory panels; conducted healthcare assessments; and developed and directed initiatives focused ... care facilities, such as Federally Qualified Health Centers, hospitals, and mental health focused ...
Concussion Center Care Team | NYU Langone Health
The medical team at NYU Langone’s Concussion Center specializes in concussion care.
policy-163-ladders-scaffolds.pdf
... Page 1 of 10 Revised: September 2, 2025 APPLICATION NYU Langone Health PURPOSE To minimize the hazards ... Work Platforms Page 2 of 10 Revised: September 2, 2025 3.0 Responsibilities 3.1 Environmental Health ...
community-health-executive-summary-english.pdf
... . The CHNAA and 2025-2027 CSP continue to focus on the Lower East Side and Chinatown in Manhattan; Sunset Park ...
policy-143-hot-work.pdf
... Safety Policy Manual Policy 143 Policy: Hot Work Program Page 1 of 17 Revised: July 1, 2025 ... County or Town requirements Safety Policy Manual Policy 143 Policy: Hot Work Program Page 2 of 17 Revised ...