RELATIONSHIP BETWEEN SYNOVIAL FLUID BIOMARKERS IN ACL RECONSTRUCTED PATIENTS AND PROGRESSION OF OSTEOARTHRITIS
We will perform a cross-sectional study on 25 patients undergoing isolated ACL reconstruction (intact menisci and articular cartilage). We have previously obtained samples of synovial fluid from both knees under a previously accepted IRB (IRB: i15-00929). At 5 years post-operatively we will perform clinical MRI on both knees with measurement of cartilage morphology, and novel imaging of articular cartilage to assess collagen and proteoglycan (PG) content. We will test our primary hypothesis that the time of surgery concentration of a panel of synovial biomarkers recently described in our laboratories will correlate with the extent of cartilage loss occurring post-operatively. Primary ObjectiveTo create a biomarker-model that can predict the development of cartilage loss and post-traumatic osteoarthritis at the relatively short term 5-year follow-up timepoint through analysis of synovial fluid samples collected at the time of surgery. Secondary ObjectiveTo compare synovial fluid biomarker profiles between patients who demonstrate evidence of accelerated articular cartilage loss following ACL reconstruction using advanced MRI based imaging techniques to patients whose articular cartilage remains intact post-operatively.
A Multi-Center Prospective Registry to Evaluate the Continued Safety and Effectiveness of Arthrex Products used for Knee Sports Medicine Repair and Reconstruction
The study is being done to evaluate the effectiveness and safety profile of Arthrex knee products when used as standard of care for repair or reconstruction of soft tissues of the knee such as ligaments, tendons, or the meniscus.
BiorEsorbable SiroLimus-ElutIng Scaffold TreatmEnt for Below The Knee Disease ELITE-BTK Trial
The purpose of this research is to is to evaluate the investigational MAGNITUDE® Bioresorbable Drug-Eluting Scaffold (MAGNITUDE Scaffold) to treat narrowed or blocked leg arteries below the knee compared to the standard of care with balloon angioplasty.
Data-Driven Learning Framework for Fast Quantitative Knee Joint Mapping
We propose a rapid and robust approach for the quantitative multi-compartment assessment of knee cartilage using magnetic resonance imaging without using either exogenous contrast agent or hardware modifications as an early screening tool for osteoarthritis.
The use of cannabidiol (CBD) in pain reduction for knee osteoarthritis. A Double-Blind Randomized Control Study
This will be a multi-center, double-blinded randomized controlled study. The study is comparing pain, patient satisfaction, in two cohorts: patients with knee OA undergoing physiotherapy who receive CBD and a placebo group. Patients will be asked on treatment Day 1, 2, 7, and 14, 28, and 42 to rate their pain according to the VAS scale. Additionally, patient satisfaction will be measured.
Common Neurological Tests | NYU Langone Health
Neurological exams help the neurosurgeons at NYU Langone pinpoint the cause of your condition and develop effective treatment strategies.
Sports Medicine Injuries We Treat | NYU Langone Health
Doctors at NYU Langone’s Sports Medicine Center are dedicated to treating all types of orthopedic injuries.
Diagnosing Psoriatic Arthritis | NYU Langone Health
NYU Langone doctors perform a physical exam and use specific criteria to diagnose psoriatic arthritis.
Nonsurgical Treatment for Anterior Cruciate Ligament Tears | NYU Langone Health
NYU Langone doctors may recommend a variety of medical treatments for anterior cruciate ligament (ACL) tears, including physical therapy.
Surgery for Meniscus Tears | NYU Langone Health
NYU Langone’s orthopedic surgeons offer a full range of surgeries for meniscus tears, including partial resection and repair procedures.