Watchful Waiting for Chronic Lymphocytic Leukemia | NYU Langone Health
NYU Langone doctors may recommend delaying treatment if chronic lymphocytic leukemia progresses slowly.
Hair Loss Services | NYU Langone Health
NYU Langone dermatologists treat hair loss and hair disorders in adults and children.
The Hirschsprung Disease Research Collaborative
Hirschsprung disease (HSCR) is a neurodevelopmental defect resulting from the absence of nerve (ganglion) cells in the gastrointestinal tract. The disorder has a population incidence of 1/5,000 live births and most often occurs as an isolated phenotype. However, approximately 30% of HSCR cases are associated with other birth defects such as Down syndrome, deafness, hypopigmentation, and Congenital Central Hypoventilation syndrome (CCHS, aka Ondine’s curse). Hirschsprung disease is a genetic condition sometimes recognized with autosomal dominant and autosomal recessive inheritance, but is generally multifactorial. While several genes associated with HSCR have been identified, it is expected that additional genes play important roles in the disorder. Furthermore, much remains to be understood about the mechanisms of genetic variants involved in the disease and how variants in multiple genes interact to lead to the diverse forms of HSCR. The objective of the Hirschsprung Disease Research Collaborative (HDRC) is to build a large collection of data and biological samples of individuals with HSCR by which genetic data can be linked to detailed and accurate phenotypic information. HDRC members (surgeon champions at diverse medical centers) will collect samples and data through a multi-site study where Dr. Aravinda Chakravarti’s laboratory at NYU School of Medicine serves as the coordinating center. The data and samples collected by HDRC members will not only be available for genetic studies, but will form a biobank from which HDRC members can request access to de-identified samples and data for use in their own IRB-approved studies. The goal of the genetic studies carried out with HDRC samples is to complete the identification of HSCR susceptibility genes and to better understand the complex inheritance of HSCR in families by whole genome mapping and sequencing studies. We also intend to ascertain the frequency with which HSCR gene variants, individually and together, lead to the diverse forms of HSCR. Finally, we use these results together with the clinical information we collect to investigate possible genotype-phenotype correlations and their relationship with medical, surgical and pathological data on participants.
Chronic Obstructive Pulmonary Disease | NYU Langone Health
NYU Langone doctors offer expert care for people with chronic obstructive pulmonary disease, or COPD, including emphysema.
SELECT-SLE: A Phase 3 Program to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Moderately to Severely Active SLE
The purpose of this program is to assess the safety and efficacy of upadacitinib compared with placebo (fake drug) for the treatment of signs and symptoms in adults with moderately to severely active systemic lupus erythematosus (SLE). Upadacitinib is an experimental drug that blocks the actions of proteins known as Janus kinases (Jaks). Jaks are involved in the immune response and cell growth including blood cells. The study drug has been approved by regulatory authorities to treat other medical conditions such as rheumatoid arthritis, psoriatic arthritis, and axial spondylarthritis but is not approved to treat lupus. Therefore, the use of the study drug is investigational (experimental) for the purposes of this program.
Dysautonomia Center | NYU Langone Health
NYU Langone’s Dysautonomia Center is dedicated to improving the lives of people with autonomic disorders, offering a range of treatment options.
NYU Langone Hospital—Suffolk Wound Care and Hyperbaric Medicine | NYU Langone Health
Experts at NYU Langone Hospital—Suffolk Wound Care and Hyperbaric Medicine offer a specialized approach to healing chronic wounds.
Recovery & Support for Chronic Lymphocytic Leukemia | NYU Langone Health
NYU Langone recovery and support services are available to help manage chronic lymphocytic leukemia.
Lung Cancer Center | NYU Langone Health
Lung Cancer Center experts at NYU Langone’s Perlmutter Cancer Center provide individualized care for people with lung cancer and mesothelioma.
Our Occupational & Industrial Orthopedic Center Team | NYU Langone Health
The staff at NYU Langone Occupational and Industrial Orthopedic Center is composed of a range of specialists in musculoskeletal disorders.