Behcet’s Disease Recovery & Support | NYU Langone Health
NYU Langone rheumatologists offer care over the long term for people with Behçet’s disease.
Benign Vocal Cord Lesions | NYU Langone Health
Voice specialists at NYU Langone offer expert diagnosis and treatment of benign vocal cord lesions using new technologies, procedures, and voice therapy.
Better health starts with a better health system. | NYU Langone Health
At NYU Langone Health, we believe that better health starts with a better health system.
bhng 0A Phase 1/2 Open-label Study to Investigate the Safety Efficacy and Pharmacokinetics of Administration of Subcutaneous Blinatumomab for the Treatment of Adults with Relapsed or Refractory B cell Precursor Acute Lymphoblastic Leukemia (R/R B-ALL)
This is a multicenter, single arm, open-label, combined 2-part phase 1/2 dose escalation and expansion study in adult subjects with R/R B-ALL, evaluating the safety, tolerability, pharmacokinetic (PK), and efficacy of SC blinatumomab as monotherapy. The first part (phase 1 [Ph1]) is a dose-finding study to investigate the PK, safety, and clinical activity of escalating dose levels of SC blinatumomab in adults (age ? 18 years) with R/R B-ALL. Once a recommended dose has been selected in the phase 1 (Ph 1) part of the study, the phase 2 (Ph2) part will begin to assess the safety and efficacy of the recommended dose level of SC blinatumomab in adults.The study will evaluate SC administration of blinatumomab as a potentially moreconvenient mode of administration and explore higher doses in the dose escalation(Ph1) part of the study and will be conducted at approximately 40 sites. The study willconsist of up to a 3-week screening and pre-phase period, a treatment period, a safetyfollow-up visit 30 (? 3) days after last dose of study treatment, and a long-term follow-up period (for Ph2 only) lasting approximately 2 years after the first dose of investigational product (IP) is received.
Bile Duct Cancer | NYU Langone Health
At NYU Langone’s Perlmutter Cancer Center, our experts diagnose and treat bile duct cancer and other liver conditions.
Biliary Atresia in Children | NYU Langone Health
Experts at Hassenfeld Children’s Hospital at NYU Langone diagnose and treat babies with biliary atresia, which causes blockages in bile ducts.
Biological and Imaging Markers to Understand and Predict Progression of Joint Damage after Injury
This study aims to study joint health after an anterior cruciate ligament (ACL) (band of tissue in the knee) injury both in the short and long term. We will look at how the body responds to injury by measuring markers in synovial fluid (SF, a thick liquid located between your joints) and gathering knee images with magnetic resonance imaging (MRI).
Biology of Blood Cells in Healthy Volunteers
The purpose of the study is to investigate immune cell and platelet physiology in a healthy population, as immune response and platelet activity has been speculated to play a role in aneurysm formation.We hope to determine the baseline immune cell and platelet properties in a healthy population.
Biomarker and Edema Attenuation in IntraCerebral hemorrhage (BEACH)
This first-in-patient phase 2a pilot study will assess the safety and tolerability of MW01-6-189WH (hereafter called MW189) in patients with Intracerebral Hemorrhage (ICH). This study will monitor exploratory radiographic and clinical endpoints, explore the use of biochemical biomarkers to demonstrate target engagement and biological response to a potential new therapy targeted to neuroinflammation and synaptic dysfunction mechanisms.
Biomarker Liquid Observation Of Mothers (BLOOM)
The purpose of this study is to learn more about postpartum depression, a mental health problem that affects some women after they give birth. Mothers with postpartum depression can feel very sad, lose interest in things they used to enjoy, have trouble sleeping, have low self-esteem, feel guilty a lot, and have trouble thinking clearly. It can also affect how babies grow and develop emotionally and behaviorally in the long run. We are interested in finding biological predictors of postpartum depression in body fluids, including blood, saliva, and cerebrospinal fluid - the liquid surrounding the brain and spinal cord. After collecting these specimens during delivery, we will survey different biological molecules, looking for specific predictors of postpartum depression. We are looking for pregnant women scheduled to deliver by Cesarean section, in which accessing these body liquids is medically required. Women participating in our study will also be asked to fill out a short online survey a few times post-delivery. Our long-term goal is to use our results to predict which women are at risk for postpartum depression to be able to predict, prevent, and treat such mothers to promote their and their children's mental health.