Intra-Individual Variability in Cognitive Performance as a Marker of Prodromal Disability in MS
The purpose of this research study is to develop a way of detecting the very early signs of cognitive decline in patients with Multiple Sclerosis (MS). The researchers will analyze cognitive performance (thinking abilities) as well as brain activity using magnetic resonance imaging (MRI) and transcranial direct current stimulation (tDCS). MRI is a routine medical procedure that takes pictures of the body, in this case, the brain. tDCS is a non-invasive brain stimulation that applies low electrical current to the brain. The researchers are using tDCS to help with obtaining images of brain activity and it is not intended as treatment.
Intradialytic Myocardial Study Stunning in Maintenance Hemodialysis Patients: A Multi-Center Observational Cohort Study
The purpose of this observational study is to prospectively investigate the frequency and risk factors for intradialytic myocardial stunning (IDMS--transient changes in how well the heart pumps during dialysis) in maintenance hemodialysis patients, to evaluate the prevalence of repetitive IDMS, and to investigate the role of cardiovascular autonomic control in IDMS pathophysiology using a battery of autonomic function tests (tests of the nervous system) during dialysis and on non-dialysis days. All subjects will undergo pre- and intradialytic echocardiography during a single hemodialysis session. There will be four substudies: Substudy A: a subset of participants will undergo repeat echocardiography during a 2nd session to assess the frequency of repetitive IDS Substudy B: a subset of participants will undergo intradialytic testing of autonomic function during a single hemodialysis session during the baseline echocardiography scanning Substudy C: a subset of participants will undergo autonomic function testing on a non-dialysis day Substudy D: a subset of participants will undergo myocardial sympathetic PET scanning--a radiology test to analyze the function of the heart nervous system--in order to assess myocardial uptake of neuro-sympathetic hormones
Intraocular Melanoma in Adults | NYU Langone Health
Perlmutter Cancer Center specialists offer expert care for people with intraocular melanoma, or choroidal melanoma, a cancer that begins in the eye.
Intrathecal Therapy for Acute Myeloid Leukemia | NYU Langone Health
NYU Langone doctors may recommend intrathecal therapy to destroy leukemia cells for people with acute myeloid leukemia.
Intrathecal Therapy for Leukemia in Children | NYU Langone Health
Doctors at Hassenfeld Children’s Hospital recommend intrathecal therapy to protect the central nervous system during chemotherapy for acute childhood leukemia.
Intrathecal Therapy for Non-Hodgkin Lymphoma in Children | NYU Langone Health
Doctors at Hassenfeld Children’s Hospital at NYU Langone use intrathecal therapy to protect the central nervous system during chemotherapy.
Intravenous Treatment for Sepsis in Children | NYU Langone Health
At Hassenfeld Children’s Hospital at NYU Langone, children with sepsis receive IV treatments to combat infection and symptoms.
Intravesical Therapy for Bladder Cancer | NYU Langone Health
Doctors at NYU Langone’s Perlmutter Cancer Center may use intravesical immunotherapy or intravesical chemotherapy to treat bladder cancer.
INTREPId (INTermediate Risk Erection PreservatIon Trial): A Randomized Trial of Radiation Therapy and Darolutamide for Prostate Cancer
The purpose of the trial is to determine whether Darolutamide plus radiation therapy (RT) is non-inferior to gonadotropin releasing hormone (GnRH) agonist and bicalutamide plus RT for intermediate risk prostate cancer. The goal of this trial is to determine whether men who receive Darolutamide with RT are better able to preserve erectile function without sacrificing the potential for long-term disease control.
Investigating the Temperature Dependence of Age-related Tau Pathology Relevant to Early Alzheimer's Disease
The purpose of this study is to assess how day to day patterns in how your body temperature naturally varies over time may contribute to increasing risk for developing Alzheimer’s disease. The study will enroll 120 adults aged between 60–80 years. We will be testing to see whether specific patterns in body temperature, recorded over 2 days, are associated with results from several tests. These tests will include cognitive evaluations, a PET-MR scan, and a blood test. During the two days we measure your body temperature, we will ask you to visit the sleep lab at night to have your sleep assessed, because body temperature and sleep are closely related. We hope to identify the mechanisms by which age-related body temperature and sleep changes contribute to AD neurodegeneration in normal elderly patients, the group that could profit the most from sleep improvement strategies.