Evaluation of the Navitor Transcatheter Heart Valve in Low and Intermediate Risk Patients who have Severe Symptomatic Aortic Stenosis Requiring Aortic Valve Replacement
Aortic stenosis is a type of heart valve disease where the valve located between the lower left heart chamber and the body’s main artery (aorta) becomes narrowed and cannot open completely. This narrowing of the valve reduces or blocks the blood flow from the heart to the rest of the body. The treatment for severe aortic stenosis is aortic valve replacement. While aortic valve replacement has traditionally been done through open heart surgery, a less invasive technique called transcatheter aortic valve implantation (TAVI) has become an alternative option for patients. The Navitor TAVI System has been Food and Drug Administration (FDA) approved for patients with symptomatic, severe aortic stenosis who are at high or extreme risk for open heart surgery. The purpose of this research study is to expand the indication of the Navitor TAVI System to patients at intermediate and low risk for open heart surgery. The safety and effectiveness of the Navitor TAVI System will be compared to that of any commercially available transcatheter aortic valve system approved by FDA for treating patients considered intermediate or low risk.
Evaluation of the Navitor Transcatheter Heart Valve in Low and Intermediate Surgical Risk Patients who have Severe Symptomatic Aortic Stenosis Requiring Aortic Valve Replacement
The ENVISION Clinical Trial is studying theNavitor™ Transcatheter Aortic Valve Implantation(TAVI) System in patients with severe,symptomatic aortic stenosis who are deemedlow or intermediate surgical risk. Approximately 1,500 patients will be studied atup to 95 centers globally. A select team ofphysicians will monitor the patients includedin the ENVISION Clinical Trial. Clinical trial participants will play an importantrole in helping physicians evaluate the use of theNavitor TAVI System for patients with severeaortic stenosis.
EVEREST-2: A Seamless Phase 1/2 Study to Evaluate the Safety and Efficacy of A2B694 an Autologous Logic-gated Tmod CAR T in Heterozygous HLA-A*02 Adults with Recurrent Unresectable Locally Advanced or Metastatic Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
econditioning lymphodepletion) for different cancers that express mesothelin (MSLN). First, the study team will test it on a small number of patients to see if it has few side effects and if it is effective in treating the cancers. Then, they'll include more patients to check there are few side effects again and see how well it works. If it seems effective with few side effects, they study team will continue testing it on more patients with different types of cancer. The study team will closely watch how the treatment works for each type of cancer. If it doesn't seem to be helping enough for a specific type of cancer, they might not include more patients with that cancer type. All the patients in the second part of the study will get the best dosage found from the first part of the study.
Every patient has one electronic record, streamlining care system-wide | NYU Langone Health
At NYU Langone, our patients use one electronic health record to streamline and integrate care across the health system.
Evoked Compound Action Potentials for Parkinson's Disease (eCAP-PD) Study
The purpose of this research is to see whether the study device, the Evoke® SCS System, is safe and works to treat Parkinson’s disease symptoms. The Evoke Spinal Cord Stimulator is FDA approved for and routinely used to treat chronic pain, but it has not been tested to know whether it helps treat Parkinson’s Disease symptoms.
Executive Administration & Musculoskeletal Advisory Board at NYU Langone Orthopedic Hospital | NYU Langone Health
NYU Langone Orthopedic Hospital is led by an executive administration and musculoskeletal advisory board.
Executive Administration at NYU Langone Hospital—Long Island | NYU Langone Health
NYU Winthrop Hospital achieves excellence through the leadership of its senior executives and medical experts.
Executive Administration at NYU Langone Hospital—Suffolk | NYU Langone Health
We use cookies and similar tools to give you the best website experience. By using our site, you accept ...
Executive Physicals | NYU Langone Health
NYU Langone offers executive physicals, providing diagnostic testing and medical referrals.
Exercise & Cardiovascular Wellness Programs | NYU Langone Health
The team at NYU Langone’s Center for the Prevention of Cardiovascular Disease helps people start and maintain a heart-healthy exercise routine.