Monitoring and Prediction of Treatment Response in Crohn s Disease with Dual-Energy CT Enterography
This will be a quantitative, prospective study. Patients with small bowel Crohn’s will be enrolled in the study. Patients will undergo an initial DECTE prior to starting a new therapy as is already performed by standard of care. Following implementation of medical therapy, patients will undergo a follow-up DECTE 4 to 8 months later as is performed by standard of care. Medical therapies are at the discretion of the gastroenterologist caring for the patient as per standard of care. The iodine density will be determined and 3D iodine density maps will be created for each patient at the time of both DECTE examinations. We will be required to record patient name, MRN, accession number of each CT, patient age, gender, and clinical data including the Crohn’s disease activity index (CDAI), which is a calculated score based on a combination of clinical and laboratory values that do not involve PHI. PHI (MRN, accession number, name, dates of scans) will be used to identify patients for inclusion in the study and for comparison with follow-up imaging. All PHI will be removed at the earliest opportunity. The age, gender and initial clinical information will be recorded while first identifying patients. Clinical information will also be recorded at the time of follow-up CT. Following the 2nd DECTE, all PHI including MRN and accession number will be discarded. Each patient will be assigned a random identification number for anonymous image review. No link to PHI will be maintained.
Monitoring outcomes of new disease modifying interventions and optimization of risk assessment in Alzheimer's disease
The purpose of this study is to develop an easier way to predict brain changes that might occur from Alzheimer's treatments, especially those using antibody therapies like Leqembi (Lecanemab). These therapies can occasionally cause brain changes, like swelling or small internal bleeding, which are usually harmless but sometimes can cause symptoms like headaches or confusion. Normally, these changes are monitored with MRI scans. However, we want to see if a simple blood test could serve as a more convenient alternative to MRIs.
Mood Disorders Consultation Service | NYU Langone Health
Specialists at NYU Langone’s Mood Disorders Consultation Service offer diagnosis and treatment for depression and mood disorders in adults.
Mood Disorders in Children | NYU Langone Health
Specialists at the Child Study Center, part of Hassenfeld Children’s Hospital at NYU Langone diagnose and treat mood disorders in children of all ages.
Movement Disorder Genomic Study
With the present study we aim to perform integrated genomic analysis and study on subject-specific cellular models in order to identify genetic causes of rare or undiagnosed movement disorders. This study will allow to further assess undiagnosed cases and offer the possibility of offering molecular diagnoses to subjects still waiting for a better definition of their conditions.
Movement Disorders | NYU Langone Health
Experts at NYU Langone’s Fresco Institute for Parkinson’s and Movement Disorders diagnose and treat people who have these neurological disorders.
MRI for Monitoring Osteoporosis Therapy Response
Patients will undergo a DXA scan to measure bone mineral density and a non-contrast (=3 T) MRI scan of the hip to assess bone microarchitectural and strength parameters. For patients who cannot tolerate the MRI scan of the hip, which requires being inside the scanner all the way, we can offer scanning of the more distal extremities (either distal femur, tibia, or radius), which will still allow assessment of bone microarchitecture. As stated above, we will also record clinical data, which are obtained as part of standard-of-care, including subjects’ FRAX scores, lab tests, and disease activity scores.
MRI Scans | NYU Langone Health
MRI scans are noninvasive medical tests that help doctors at NYU Langone diagnose certain conditions.
MS Palliative Care | NYU Langone Health
The MS Palliative Care Center at NYU Langone’s Multiple Sclerosis Comprehensive Care Center offers supportive care to people with MS and their families.
Multi-Center Prospective Cervical Radiculopathy and Myelopathy of Adult Surgical Patients
The objective of this study is to develop a clinical registry of patients diagnosed with cervical radiculopathy or cervical myelopathy over a 3 year period. Target enrollment is 1000 patients over 3 years with at least 25 participating sites. The registry will capture radiographic, demographic, and diagnosis related data, as well as patient-reported outcomes. Data will be entered into a centralized, HIPAA compliant database. The registry data will be de-identified.