Inflammatory Bowel Disease Research Program | NYU Langone Health

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Inflammatory Bowel Disease Research Program

Our work turns basic science discoveries into treatments for inflammatory bowel diseases.

The Inflammatory Bowel Disease Research Program at NYU Langone Health bridges basic, clinical, and educational disciplines and brings together faculty who build on the breadth of our immunology, microbiology, and cell biology research to foster cross-disciplinary collaborations and studies. Our mission is to build on our institution’s tradition of turning basic science discoveries into treatments for inflammatory bowel diseases (IBD) including Crohn’s disease and ulcerative colitis.

Following their research on immune signaling molecules, NYU Langone microbiologists worked with pharmaceutical companies to develop the drug infliximab, which blocks one such molecule called TNF-α. It remains among the most commonly used therapies for IBD.

Faculty at the Inflammatory Bowel Disease Research Program work hand-in-hand with gastroenterologists and surgeons at NYU Langone’s clinical Inflammatory Bowel Disease Center with the goal of discovering new treatment strategies and how best to apply them to improve patient care.

Our Leadership

Jordan E. Axelrad, MD, MPH, is our program director. Dr. Axelrad is recognized for his research on malignant and infectious complications of IBD, specifically, in elucidating how exposures such as gastrointestinal infections may complicate IBD or trigger it to develop.

David P. Hudesman, MD, is the director of our Inflammatory Bowel Disease Center. Together with Dr. Axelrad, they manage IBD research studies and clinical trials representing partnerships among clinicians, scientists, and industry.

Available Positions

We are hiring research scientists to join our team. Learn more about our available positions.

Select Faculty Publications

AGA Clinical Practice Update on Management of Inflammatory Bowel Disease in Patients With Malignancy: Commentary

Axelrad, Jordan E; Hashash, Jana G; Itzkowitz, Steven H

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2024 Jul ; 22:1365-1372

Prevention of Psoriatic Arthritis: The Need for Prospective Studies

Wu, Alexander; Scher, Jose U; Ogdie, Alexis; Ritchlin, Christopher; Merola, Joseph F

Dermatologic clinics. 2024 Jul ; 42:429-438

SARS-CoV-2 inflammation durably imprints memory CD4 T cells

Gray-Gaillard, Sophie L; Solis, Sabrina M; Chen, Han M; Monteiro, Clarice; Ciabattoni, Grace; Samanovic, Marie I; Cornelius, Amber R; Williams, Tijaana; Geesey, Emilie; Rodriguez, Miguel; Ortigoza, Mila Brum; Ivanova, Ellie N; Koralov, Sergei B; Mulligan, Mark J; Herati, Ramin Sedaghat

Science immunology. 2024 Jun 21; 9:eadj8526

Clinical validation of digital assessment tools and machine learning models for remote measurement of psoriasis and psoriatic arthritis: a proof-of-concept study

Webster, Dan E; Haberman, Rebecca H; Chada, Lourdes Maria Perez; Tummalacherla, Meghasyam; Tediarjo, Aryton; Yadav, Vijay; Neto, Elias Chaibub; MacDuffie, Woody; DePhillips, Michael; Sieg, Eric; Catron, Sydney; Grant, Carly; Francis, Wynona; Nguyen, Marina; Yussuff, Muibat; Castillo, Rochelle L; Yan, Di; Neimann, Andrea L; Reddy, Soumya M; Ogdie, Alexis; Kolivras, Athanassios; Kellen, Michael R; Mangravite, Lara M; Sieberts, Solveig K; Omberg, Larsson; Merola, Joseph F; Scher, Jose U

The Journal of rheumatology. 2024 Jun 15;

Genetic and environmental interactions contribute to immune variation in rewilded mice

Oyesola, Oyebola; Downie, Alexander E; Howard, Nina; Barre, Ramya S; Kiwanuka, Kasalina; Zaldana, Kimberly; Chen, Ying-Han; Menezes, Arthur; Lee, Soo Ching; Devlin, Joseph; Mondragón-Palomino, Octavio; Souza, Camila Oliveira Silva; Herrmann, Christin; Koralov, Sergei B; Cadwell, Ken; Graham, Andrea L; Loke, P'ng

Nature immunology. 2024 Jun 14;

Cardiometabolic Comorbidity Burden and Circulating Biomarkers in Patients with Chronic Coronary Disease in the ISCHEMIA Trials

Hamo, Carine E; Liu, Richard; Wu, Wenbo; Anthopolos, Rebecca; Bangalore, Sripal; Held, Claes; Kullo, Ifitkhar; Mavromatis, Kreton; McManus, Bruce; Newby, L Kristin; Reynolds, Harmony R; Ruggles, Kelly V; Wallentin, Lars; Maron, David J; Hochman, Judith S; Newman, Jonathan D; Berger, Jeffrey S; ,

The American journal of cardiology. 2024 Jun 04;

The Management of Colorectal Neoplasia in Patients With Inflammatory Bowel Disease

Axelrad, Jordan E; Rubin, David T

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2024 Jun ; 22:1181-1185

Multiomics Assessment of the Gut Microbiome in Rare Hyperoxaluric Conditions

Zaidan, Nadim; Wang, Chan; Chen, Ze; Lieske, John C; Milliner, Dawn; Seide, Barbara; Ho, Melody; Li, Huilin; Ruggles, Kelly V; Modersitzki, Frank; Goldfarb, David S; Blaser, Martin; Nazzal, Lama

Kidney international reports. 2024 Jun ; 9:1836-1848