Chiara Giannarelli

Chiara Giannarelli, MD, PhD

Associate Professor, Department of Medicine

Associate Professor, Department of Pathology

Positions

Associate Professor, Department of Medicine at NYU Grossman School of Medicine

Associate Professor, Department of Pathology at NYU Grossman School of Medicine

Graduate Education

PhD from University of Pisa

MD from University of Pisa

Lab Website
Giannarelli Lab
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Investigation of cellular and molecular interactions in inflammation angiogenesis and immunity in human atherosclerosis: the ATHERO-IN study

CHORD1 CHOlesterol Lowering and Residual Risk in Diabetes Type 1

PERSPIRE: A pilot study of Pro-rEsolving and pRo-inflammatory reSPonses to acute exhaustIve exeRcisE in healthy individuals

See All Studies (3)

Phthalate exposure from plastics and cardiovascular disease: global estimates of attributable mortality and years life lost

Hyman, Sara; Acevedo, Jonathan; Giannarelli, Chiara; Trasande, Leonardo

EBioMedicine. 2025 Apr 25; 105730

Immune checkpoint landscape of human atherosclerosis and influence of cardiometabolic factors

Barcia Durán, José Gabriel; Das, Dayasagar; Gildea, Michael; Amadori, Letizia; Gourvest, Morgane; Kaur, Ravneet; Eberhardt, Natalia; Smyrnis, Panagiotis; Cilhoroz, Burak; Sajja, Swathy; Rahman, Karishma; Fernandez, Dawn M; Faries, Peter; Narula, Navneet; Vanguri, Rami; Goldberg, Ira J; Fisher, Edward A; Berger, Jeffrey S; Moore, Kathryn J; Giannarelli, Chiara

Nature cardiovascular research. 2024 Dec; 3(12):1482-1502

Decoding Macrophage Heterogeneity to Unravel Vascular Inflammation as a Path to Precision Medicine

Chelvanambi, Sarvesh; Decano, Julius L; Winkels, Holger; Giannarelli, Chiara; Aikawa, Masanori

Arteriosclerosis, thrombosis, & vascular biology. 2024 Nov; 44(11):2253-2257

The IRG1-itaconate axis protects from cholesterol-induced inflammation and atherosclerosis

Cyr, Yannick; Bozal, Fazli K; Barcia Durán, José Gabriel; Newman, Alexandra A C; Amadori, Letizia; Smyrnis, Panagiotis; Gourvest, Morgane; Das, Dayasagar; Gildea, Michael; Kaur, Ravneet; Zhang, Tracy; Wang, Kristin M; Von Itter, Richard; Schlegel, P Martin; Dupuis, Samantha D; Sanchez, Bernard F; Schmidt, Ann Marie; Fisher, Edward A; van Solingen, Coen; Giannarelli, Chiara; Moore, Kathryn J

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2024 Apr 09; 121(15):e2400675121

BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer's disease and other disorders of lipid-rich tissues

Podleśny-Drabiniok, Anna; Novikova, Gloriia; Liu, Yiyuan; Dunst, Josefine; Temizer, Rose; Giannarelli, Chiara; Marro, Samuele; Kreslavsky, Taras; Marcora, Edoardo; Goate, Alison Mary

Nature communications. 2024 Mar 06; 15(1):2058

SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels

Eberhardt, Natalia; Noval, Maria Gabriela; Kaur, Ravneet; Amadori, Letizia; Gildea, Michael; Sajja, Swathy; Das, Dayasagar; Cilhoroz, Burak; Stewart, O'Jay; Fernandez, Dawn M; Shamailova, Roza; Guillen, Andrea Vasquez; Jangra, Sonia; Schotsaert, Michael; Newman, Jonathan D; Faries, Peter; Maldonado, Thomas; Rockman, Caron; Rapkiewicz, Amy; Stapleford, Kenneth A; Narula, Navneet; Moore, Kathryn J; Giannarelli, Chiara

Nature cardiovascular research. 2023 Oct; 2(10):899-916

Systems immunology-based drug repurposing framework to target inflammation in atherosclerosis

Amadori, Letizia; Calcagno, Claudia; Fernandez, Dawn M; Koplev, Simon; Fernandez, Nicolas; Kaur, Ravneet; Mury, Pauline; Khan, Nayaab S; Sajja, Swathy; Shamailova, Roza; Cyr, Yannick; Jeon, Minji; Hill, Christopher A; Chong, Peik Sean; Naidu, Sonum; Sakurai, Ken; Ghotbi, Adam Ali; Soler, Raphael; Eberhardt, Natalia; Rahman, Adeeb; Faries, Peter; Moore, Kathryn J; Fayad, Zahi A; Ma'ayan, Avi; Giannarelli, Chiara

Nature cardiovascular research. 2023 Jun; 2(6):550-571

Macrophage-Derived 25-Hydroxycholesterol Promotes Vascular Inflammation, Atherogenesis, and Lesion Remodeling

Canfrán-Duque, Alberto; Rotllan, Noemi; Zhang, Xinbo; Andrés-Blasco, Irene; Thompson, Bonne M; Sun, Jonathan; Price, Nathan L; Fernández-Fuertes, Marta; Fowler, Joseph W; Gómez-Coronado, Diego; Sessa, William C; Giannarelli, Chiara; Schneider, Robert J; Tellides, George; McDonald, Jeffrey G; Fernández-Hernando, Carlos; Suárez, Yajaira

Circulation. 2023 Jan 31; 147(5):388-408

See All Publications (92)

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