Dmitry Novikov

Dmitry Novikov, PhD

Associate Professor, Department of Radiology

Keywords
tissue microstructure, magnetic resonance imaging, biophysics, diffusion, modeling
Summary

I use analytical and numerical modeling methods to quantify and interpret cellular-level tissue structure and its changes in disease based on various MRI contrasts. Biophysical modeling of diffusion and NMR relaxation makes it possible to become specific to tissue features 100-1000 times below the nominal MRI resolution. Specifically, I focus on MRI measurements of diffusion and transverse relaxation to quantify the structure and sizes of cells, their membrane permeability, and the amount of accumulated iron, and to identify quantitative disease biomarkers in neurodegenerative diseases, tumors, and myopathies.

Phone

212-263-2718

Academic office

227 E 30th St

7, 724

New York, NY 10016

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Positions

Associate Professor, Department of Radiology at NYU Grossman School of Medicine

Graduate Education

PhD from Massachusetts Institute of Technology

Postdoctoral Training

Princeton University, Physics

Yale University, Physics

Development of RPBM for Quantitative Assessment of Myofascial Pain

Technical Development and Optimization for Random Matrix Theory-Based Magnetic Resonance Imaging

Unpacking the Importance of the Structural Injuries of MTBI

Mesoscopic Biomarkers of Neurodegeneration and Inflammation with Diffusion MRI

See All Studies (6)

Linking Symptom Phenotypes to Patterns of White Matter Injury in Mild Traumatic Brain Injury: A Latent Class Analysis

Chung, Sohae; Shin, Seon-Hi; Alivar, Alaleh; McGiffin, Jed N; Coelho, Santiago; Rath, Joseph F; Fieremans, Els; Novikov, Dmitry S; El Berkaoui, Ali; Foo, Farng-Yang; Rashbaum, Ira G; Amorapanth, Prin; Flanagan, Steven R; Lui, Yvonne W

AJNR. American journal of neuroradiology. 2026 May 04; 47(5):1400-1405

What If Each Voxel Were Measured With a Different Diffusion Protocol?

Coelho, Santiago; Lemberskiy, Gregory; Zhu, Ante; Lee, Hong-Hsi; Abad, Nastaren; Foo, Thomas K F; Fieremans, Els; Novikov, Dmitry S

Magnetic resonance in medicine. 2026 Apr; 95(4):2277-2290

Simulation-Informed Evaluation of Microvascular Parameter Mapping for Diffusion MR Imaging of Solid Tumours

Voronova, Anna Kira; Prior, Olivia; Grigoriou, Athanasios; Salvà, Francesc; Elez, Elena; Atlagich, Luz M; Sala-Llonch, Roser; Palombo, Marco; Fieremans, Els; Novikov, Dmitry S; Perez-Lopez, Raquel; Grussu, Francesco

Magnetic resonance in medicine. 2026 Mar 07;

White matter microstructure differences in obstructive sleep apnea severity groups assessed by diffusion tensor metrics and biophysical modeling

Figueredo, Luisa F; Chen, Jenny; Gaggi, Naomi L; Song, Xiaotong; Jacobs, Tovia; Silva-Albornoz, Gabriela; Pehel, Shayna; Gonzalez, Moses; Badia, Sandra Giménez; Rosenzweig, Ivana; Naismith, Sharon L; Ramos-Cejudo, Jaime; Gills, Joshua; Ayappa, Indu; Rapoport, David M; Kam, Korey; Mullins, Anna E; Parekh, Ankit; Varga, Andrew W; Bubu, Omonigho M; Blessing, Esther; Novikov, Dmitry S; Fieremans, Els; Osorio, Ricardo S

Scientific reports. 2026 Mar 04; 16(1):

Histology-informed microstructural diffusion simulations for MRI cancer characterisation-the Histo-μSim framework

Grigoriou, Athanasios; Macarro, Carlos; Palombo, Marco; Navarro-Garcia, Daniel; Voronova, Anna Kira; Bernatowicz, Kinga; Barba, Ignasi; Escriche, Alba; Greco, Emanuela; Abad, María; Simonetti, Sara; Serna, Garazi; Mast, Richard; Merino, Xavier; Roson, Núria; Escobar, Manuel; Vieito, Maria; Nuciforo, Paolo; Toledo, Rodrigo; Garralda, Elena; Sala-Llonch, Roser; Fieremans, Els; Novikov, Dmitry S; Perez-Lopez, Raquel; Grussu, Francesco

Communications biology. 2025 Nov 26; 8(1):1695

Scattering approach to diffusion quantifies axonal damage in brain injury

Abdollahzadeh, Ali; Coronado-Leija, Ricardo; Lee, Hong-Hsi; Sierra, Alejandra; Fieremans, Els; Novikov, Dmitry S

Nature communications. 2025 Nov 06; 16(1):9808

Engineering clinical translation of OGSE diffusion MRI

Zhu, Ante; Michael, Eric S; Li, Hua; Sprenger, Tim; Hua, Yihe; Lee, Seung-Kyun; Yeo, Desmond Teck Beng; McNab, Jennifer A; Hennel, Franciszek; Fieremans, Els; Wu, Dan; Foo, Thomas K F; Novikov, Dmitry S

Magnetic resonance in medicine. 2025 Sep; 94(3):913-936

Quantifying axonal features of human superficial white matter from three-dimensional multibeam serial electron microscopy data assisted by deep learning

Tian, Qiyuan; Ngamsombat, Chanon; Lee, Hong-Hsi; Berger, Daniel R; Wu, Yuelong; Fan, Qiuyun; Bilgic, Berkin; Li, Ziyu; Novikov, Dmitry S; Fieremans, Els; Rosen, Bruce R; Lichtman, Jeff W; Huang, Susie Y

Neuroimage. 2025 Apr 11; 121212

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