Dmitry Novikov

Dmitry Novikov, PhD

Associate Professor, Department of Radiology

Keywords
tissue microstructure, magnetic resonance imaging, biophysics, diffusion, modeling
Summary

I use analytical and numerical modeling methods to quantify and interpret cellular-level tissue structure and its changes in disease based on various MRI contrasts. Biophysical modeling of diffusion and NMR relaxation makes it possible to become specific to tissue features 100-1000 times below the nominal MRI resolution. Specifically, I focus on MRI measurements of diffusion and transverse relaxation to quantify the structure and sizes of cells, their membrane permeability, and the amount of accumulated iron, and to identify quantitative disease biomarkers in neurodegenerative diseases, tumors, and myopathies.

Phone

212-263-2718

Academic office

227 E 30th St

7, 724

New York, NY 10016

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Positions

Associate Professor, Department of Radiology at NYU Grossman School of Medicine

Graduate Education

PhD from Massachusetts Institute of Technology

Postdoctoral Training

Princeton University, Physics

Yale University, Physics

Technical Development and Optimization for Random Matrix Theory-Based Magnetic Resonance Imaging

Unpacking the Importance of the Structural Injuries of MTBI

Mesoscopic Biomarkers of Neurodegeneration and Inflammation with Diffusion MRI

Optimized sodium MR imaging at clinical field strength to study in vivo sodium signal in mild traumatic brain injury

See All Studies (4)

Quantifying axonal features of human superficial white matter from three-dimensional multibeam serial electron microscopy data assisted by deep learning

Tian, Qiyuan; Ngamsombat, Chanon; Lee, Hong-Hsi; Berger, Daniel R; Wu, Yuelong; Fan, Qiuyun; Bilgic, Berkin; Li, Ziyu; Novikov, Dmitry S; Fieremans, Els; Rosen, Bruce R; Lichtman, Jeff W; Huang, Susie Y

NeuroImage. 2025 Apr 11; 121212

SpinFlowSim: A blood flow simulation framework for histology-informed diffusion MRI microvasculature mapping in cancer

Voronova, Anna Kira; Grigoriou, Athanasios; Bernatowicz, Kinga; Simonetti, Sara; Serna, Garazi; Roson, Núria; Escobar, Manuel; Vieito, Maria; Nuciforo, Paolo; Toledo, Rodrigo; Garralda, Elena; Fieremans, Els; Novikov, Dmitry S; Palombo, Marco; Perez-Lopez, Raquel; Grussu, Francesco

Medical image analysis. 2025 Mar 07; 102:103531

Revealing membrane integrity and cell size from diffusion kurtosis time dependence

Lee, Hong-Hsi; Novikov, Dmitry S; Fieremans, Els; Huang, Susie Y

Magnetic resonance in medicine. 2025 Mar; 93(3):1329-1347

Denoising Improves Cross-Scanner and Cross-Protocol Test-Retest Reproducibility of Diffusion Tensor and Kurtosis Imaging

Ades-Aron, Benjamin; Coelho, Santiago; Lemberskiy, Gregory; Veraart, Jelle; Baete, Steven H; Shepherd, Timothy M; Novikov, Dmitry S; Fieremans, Els

Human brain mapping. 2025 Mar; 46(4):e70142

Microstructurally informed subject-specific parcellation of the corpus callosum using axonal water fraction

Chung, Sohae; Fieremans, Els; Novikov, Dmitry S; Lui, Yvonne W

Brain structure & function. 2024 Dec 13; 230(1):1

In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI

Wu, Dan; Lee, Hong-Hsi; Ba, Ruicheng; Turnbill, Victoria; Wang, Xiaoli; Luo, Yu; Walczak, Piotr; Fieremans, Els; Novikov, Dmitry S; Martin, Lee J; Northington, Frances J; Zhang, Jiangyang

Science advances. 2024 Jul 19; 10(29):eadk1817

Signatures of microstructure in gradient-echo and spin-echo signals

Storey, Pippa; Novikov, Dmitry S

Magnetic resonance in medicine. 2024 Jul; 92(1):269-288

Callosal Interhemispheric Communication in Mild Traumatic Brain Injury: A Mediation Analysis on WM Microstructure Effects

Chung, Sohae; Bacon, Tamar; Rath, Joseph F; Alivar, Alaleh; Coelho, Santiago; Amorapanth, Prin; Fieremans, Els; Novikov, Dmitry S; Flanagan, Steven R; Bacon, Joshua H; Lui, Yvonne W

AJNR. American journal of neuroradiology. 2024 Jun 07; 45(6):788-794

See All Publications (113)

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