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Guillaume Madelin

Guillaume Madelin, PhD

Assistant Professor, Department of Radiology

Magnetic Resonance Imaging (MRI), X-Nuclei (Sodium, Phosphorus, Deuterium, Oxygen) MRI, Metabolic Imaging, Non-Cartesian MRI, Ultrashort Echo Time (UTE) MRI, Neuroimaging, Musculoskeletal Imaging, Cancer Imaging, MR Physics

I am developing a global project of "quantitative metabolic X-nuclei magnetic resonance imaging (MRI) in vivo for medical applications". X-nuclei MRI is based on the detection of nuclei other than the nucleus of hydrogen (or proton, 1H) from water molecules in the body, as is used in standard MRI. MRI of the sodium (23Na), phosphorus (31P), deuterium (2H), or oxygen (17O) nuclei, for example, can provide brand new metabolic information in tissues as a complement to standard structural 1H MRI. In particular, imaging of endogenous sodium is a non-invasive quantitative technique that can assess fundamental biochemical information related to the tissue ionic homeostasis, which is not available with any other imaging technique in vivo. Overall, X-nuclei MRI could therefore generate unique imaging biomarkers for detecting early signs of loss of tissue viability due to the disruption of the cellular energetic metabolism in many diseases, but also for monitoring the early effects of therapies targeting different aspects of cellular metabolism, and thus help design personalized treatment protocols.




Academic office

Center for Biomedical Imaging, 660 First Avenue

4th Floor

New York, NY 10016

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PhD from University of Bordeaux

Yu, Zidan; Hodono, Shota; Dergachyova, Olga; Hilbert, Tom; Wang, Bili; Zhang, Bei; Brown, Ryan; Sodickson, Daniel K; Madelin, Guillaume; Cloos, Martijn A

Magnetic resonance in medicine. 2022 May; 87(5):2299-2312

X-Nuclei Magnetic Resonance Imaging

Madelin, Guillaume

X-Nuclei Magnetic Resonance Imaging. [S.l.] : Jenny Stanford Publishing, 2022. 1st ed. (5181842)

Gerhalter, Teresa; Cloos, Martijn; Chen, Anna M; Dehkharghani, Seena; Peralta, Rosemary; Babb, James S; Zarate, Alejandro; Bushnik, Tamara; Silver, Jonathan M; Im, Brian S; Wall, Stephen; Baete, Steven; Madelin, Guillaume; Kirov, Ivan I

European radiology. 2022 Feb; 32(2):1308-1319

Krahe, Janna; Dogan, Imis; Didszun, Claire; Mirzazade, Shahram; Haeger, Alexa; Joni Shah, Nadim; Giordano, Ilaria A; Klockgether, Thomas; Madelin, Guillaume; Schulz, Jörg B; Romanzetti, Sandro; Reetz, Kathrin

NeuroImage: Clinical. 2022 Mar; 34:103025

Wang, Bili; Zhang, Bei; Yu, Zidan; Ianniello, Carlotta; Lakshmanan, Karthik; Paska, Jan; Madelin, Guillaume; Cloos, Martijn; Brown, Ryan

NMR in biomedicine. 2021 Sep 03; e4608

Gajdošík, Martin; Landheer, Karl; Swanberg, Kelley M; Adlparvar, Fatemeh; Madelin, Guillaume; Bogner, Wolfgang; Juchem, Christoph; Kirov, Ivan I

NMR in biomedicine. 2021 May 06; e4538

Tordjman, Mickael; Madelin, Guillaume; Gupta, Pradeep Kumar; Cordova, Christine; Kurz, Sylvia C; Orringer, Daniel; Golfinos, John; Kondziolka, Douglas; Ge, Yulin; Wang, Ruoyu Luie; Lazar, Mariana; Jain, Rajan

Journal of neuro-oncology. 2021 Apr; 152(2):347-355

Ianniello, Carlotta; Moy, Linda; Fogarty, Justin; Schnabel, Freya; Adams, Sylvia; Axelrod, Deborah; Axel, Leon; Brown, Ryan; Madelin, Guillaume

Scientific reports. 2021 Mar 04; 11(1):5156