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Oded Gonen

Oded Gonen, PhD

Professor Emeritus of Radiology, Department of Radiology

Magnetic Resonance Spectroscopy and its applications to cancer, neurodegenerative diseases and psychiatric disorders, development of MR-spectroscopy tools to support to medical and biomedical research, imaging

In vivo localized MR spectroscopy (MRS) facilitates non-invasive investigations of the physiology and biochemistry (as opposed to the anatomic and morphologic information from MRI). The primarily focus of our research is the human brain, and to a lesser extent, other organs, e.g., the liver and pancreas, probed by 3-dimensional localized proton (but also phosphorus-31 and fluorine-19) MRS. An example of the differences and similarities between MRI and MRS is illustrated in the figure below. Our research projects propagate along three, parallel paths: First, technique development - the design of new localization methods, based on Fourier and Hadamard spatial encoding, to accommodate the higher magnetic fields that are now becoming available, and to tailor these methods to anatomies that traditionally have been inaccessible to existing methodologies, e.g., the spinal cord, optic nerve and cortex. Second, application of these methods to characterize normal and pathological metabolism by quantitatively comparing metabolic levels in the different anatomical structures. Our current clinical focuses are the processes of normal aging, multiple sclerosis and traumatic brain injury. Finally, the third direction is post- processing and visualization methodology and software development, to display the copious 3D information in a manner that will not hide the forest for the trees, because, after all, this is a department of radiology, so here, image is everything.



Academic office

660 First Avenue

Fourth Floor

New York, NY 10016

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PhD from Hebrew University of Jerusalem

McKenna, Faye; Gupta, Pradeep Kumar; Sui, Yu Veronica; Bertisch, Hilary; Gonen, Oded; Goff, Donald C; Lazar, Mariana

Schizophrenia bulletin. 2023 Nov 29; 49(6):1542-1553

Lee, Jakleen J; Piras, Enrica; Tamburini, Sabrina; Bu, Kevin; Wallach, David S; Remsen, Brooke; Cantor, Adam; Kong, Jennifer; Goetz, Deborah; Hoffman, Kevin W; Bonner, Mharisi; Joe, Peter; Mueller, Bridget R; Robinson-Papp, Jessica; Lotan, Eyal; Gonen, Oded; Malaspina, Dolores; Clemente, Jose C

Psychiatry research. 2023 May 30; 326:115279

Mueller, Bridget; Robinson-Papp, Jessica; Suprun, Maria; Suarez-Farinas, Mayte; Lotan, Eyal; Gonen, Oded; Malaspina, Dolores

Clinical autonomic research. 2023 Apr; 33(2):101-110

Joe, Peter; Clemente, Jose C; Piras, Enrica; Wallach, David S; Robinson-Papp, Jessica; Boka, Emeka; Remsen, Brooke; Bonner, Mharisi; Kimhy, David; Goetz, Deborah; Hoffman, Kevin; Lee, Jakleen; Ruby, Eugene; Fendrich, Sarah; Gonen, Oded; Malaspina, Dolores

Schizophrenia research. 2022 Sep; 247:101-115

Fendrich, Sarah J; Koralnik, Lauren R; Bonner, Mharisi; Goetz, Deborah; Joe, Peter; Lee, Jakleen; Mueller, Bridget; Robinson-Papp, Jessica; Gonen, Oded; Clemente, Jose C; Malaspina, Dolores

Psychiatry research. 2022 Jun; 312:114526

Pires, A; Nayak, G; Zan, E; Hagiwara, M; Gonen, O; Fatterpekar, G

AJNR. American journal of neuroradiology. 2021 10; 42(10):1847-1852

Tal, Assaf; Zhao, Tiejun; Schirda, Claudiu; Hetherington, Hoby P; Pan, Jullie W; Gonen, Oded

NMR in biomedicine. 2021 Mar 23; e4507

Pan, Jullie W; Antony, Arun; Tal, Assaf; Yushmanov, Victor; Fong, Joanna; Richardson, Mark; Schirda, Claud; Bagic, Anto; Gonen, Oded; Hetherington, Hoby P

NMR in biomedicine. 2021 Mar 10; e4492