Research in Obstetrics and Gynecology

Epidemiology Research

Our division participates in the NYU Women's Health Study. To learn more about the study, including current projects, findings to date and other information, please visit the NYU Women's Health Study website.

Gynecologic Oncology Research

Our division participates in Gynecologic Oncology Group (GOG) clinical research trials evaluating new and novel treatment regimen for all gynecologic malignancies. In addition, we coordinate the National Ovarian Cancer Early Detection Program which combines genetics, ultrasound, and gynecologic oncology and is committed to the establishment of effective means for the accurate detection of early stage ovarian cancer especially in the high risk population. We also have National Cancer Institute (NCI) support for our pioneering research on the use of contrast sonography for the detection of early stage ovarian cancer.

Additionally our basic science laboratory focuses on the molecular and biochemical regulation of ovarian and endometrial metastasis.

Reproductive Biology Research

Current research in the laboratory of Frederick Naftolin, MD, D.Phil. focuses on studying the potential effects of fetal growth during development on common adult diseases. A National Institutes of Health (NIH) grant has been awarded to advance these studies. In addition, Dr. Naftolin and Lila Nachtigall, MD serve as Co-Directors of the Interdisciplinary Program in Menopause Medicine, which is dedicated to exploring possible links between menopause and a variety of chronic diseases, including cancers, Alzheimer's disease, and diabetes.

Stem Cell Research

Our department is one of the very few in the nation conducting human stem cell research. Fellows in the Division of Maternal-Fetal Medicine participate in this research in the laboratory under the direction of Dr. Bruce K. Young. One current study addresses the problem of determining the effects on the fetus of drugs taken by pregnant women. Currently only animal models or epidemiologic data acquired from human exposure can be used. Our study, “Testing pharmacologic effects on human amniotic fluid derived cell cultures for fetal risk” has developed a system for testing drugs in the laboratory using human fetal cells to predict outcomes of drug exposure during pregnancy. A series of studies under the broad title “Human amniotic fluid derived stem cells for clinical transplantation” has shown that these stem cells are an abundant and potentially useful source for stem cell transplants. Another project is in collaboration with Drs. Kirk Campbell and Thorsten Kirsch in the Department of Orthopedics to use a rabbit model for treating arthritis with stem cell transplants.

Current Clinical Trials in Obstetrics and Gynecology

A clinical trial is a research study in human volunteers to answer specific health questions. Carefully conducted investigational trials are the fastest and safest way to find treatments that work in people and ways to improve health. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings.

Additional Information

Search a database of open trials, learn more about the various types and different phases of clinical trials, and read about eligibility requirements.