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Sigurdsson Lab Sigurdsson Lab Publications

Sigurdsson Lab Publications

Investigators in the Sigurdsson Lab publish the results of their research in leading publications. Read the latest papers to learn more about our work.

Recent Publications

Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy mice

Martín-Ávila, Alejandro; Modak, Swananda R; Rajamohamedsait, Hameetha B; Dodge, Andie; Shamir, Dov B; Krishnaswamy, Senthilkumar; Sandusky-Beltran, Leslie A; Walker, Marilyn; Lin, Yan; Congdon, Erin E; Sigurdsson, Einar M

Cell reports. 2025 Sep 16; 44:116291

Formaldehyde induces and promotes Alzheimer's disease pathologies in a 3D human neural cell culture system

Wu, Peipei; Chen, Danqi; Wang, Fei; Lu, Kun; Sigurdsson, Einar M; Jin, Chunyuan

bioRxiv.org : the preprint server for biology. 2025 Mar 04;

Neuronal hypofunction and network dysfunction in a mouse model at an early stage of tauopathy

Ji, Changyi; Yang, Xiaofeng; Eleish, Mohamed; Jiang, Yixiang; Tetlow, Amber M; Song, Soomin C; Martín-Ávila, Alejandro; Wu, Qian; Zhou, Yanmei; Gan, Wenbiao; Lin, Yan; Sigurdsson, Einar M

Alzheimer's & dementia. 2024 Nov ; 20:7954-7970

Anti-tau single domain antibodies clear pathological tau and attenuate its toxicity and related functional defects

Nair, Sudershana; Jiang, Yixiang; Marchal, Isabella S; Chernobelsky, Elizabeth; Huang, Huai-Wei; Suh, Sarah; Pan, Ruimin; Kong, Xiang-Peng; Ryoo, Hyung Don; Sigurdsson, Einar M

Cell death & disease. 2024 Jul 30; 15:543

Single-domain antibody-based protein degrader for synucleinopathies

Jiang, Yixiang; Lin, Yan; Tetlow, Amber M; Pan, Ruimin; Ji, Changyi; Kong, Xiang-Peng; Congdon, Erin E; Sigurdsson, Einar M

Molecular neurodegeneration. 2024 May 31; 19:44

Neuronal hypofunction and network dysfunction in a mouse model at an early stage of tauopathy

Ji, Changyi; Yang, Xiaofeng; Eleish, Mohamed; Jiang, Yixiang; Tetlow, Amber M; Song, Soomin C; Martín-Ávila, Alejandro; Wu, Qian; Zhou, Yanmei; Gan, Wenbiao; Lin, Yan; Sigurdsson, Einar M

[Zhong ji yi kan] = [Medicine for intermediate groups]. 2024 May 01;

Single-Domain Antibody-Based Protein Degrader for Synucleinopathies

Jiang, Yixiang; Lin, Yan; Tetlow, Amber M; Pan, Ruimin; Ji, Changyi; Kong, Xiang-Peng; Congdon, Erin E; Sigurdsson, Einar M

[Zhong ji yi kan] = [Medicine for intermediate groups]. 2024 Apr 30;

Tau Immunotherapies for Alzheimer's Disease and Related Tauopathies: Status of Trials and Insights from Preclinical Studies

Sigurdsson, Einar M

Journal of Alzheimer's disease. 2024 May ; 101:S129-S140

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