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Sigurdsson Lab Sigurdsson Lab Publications

Sigurdsson Lab Publications

Investigators in the Sigurdsson Lab publish the results of their research in leading publications. Read the latest papers to learn more about our work.

Recent Publications

Tau-targeting therapies for Alzheimer disease: current status and future directions

Congdon, Erin E; Ji, Changyi; Tetlow, Amber M; Jiang, Yixiang; Sigurdsson, Einar M

Nature reviews. Neurology. 2023 Dec ; 19:715-736

Single-domain antibody-based noninvasive in vivo imaging of α-synuclein or tau pathology

Jiang, Yixiang; Lin, Yan; Krishnaswamy, Senthilkumar; Pan, Ruimin; Wu, Qian; Sandusky-Beltran, Leslie A; Liu, Mengyu; Kuo, Min-Hao; Kong, Xiang-Peng; Congdon, Erin E; Sigurdsson, Einar M

Science advances. 2023 May 10; 9:eadf3775

Development of brain-penetrable antibody radioligands for in vivo PET imaging of amyloid-β and tau

Banka, Vinay; Kelleher, Andrew; Sehlin, Dag; Hultqvist, Greta; Sigurdsson, Einar M; Syvänen, Stina; Ding, Yu-Shin

Frontiers in nuclear medicine (Lausanne, Switzerland). 2023 Sep ; 3:

Amyloid-β targeting immunisation in aged non-human primate (Microcebus murinus).

Trouche, Stéphanie G; Boutajangout, Allal; Asuni, Ayodeji; Fontés, Pascaline; Sigurdsson, Einar M; Verdier, Jean-Michel; Mestre-Francés, Nadine

Brain, behavior & immunity. 2022 Dec 30; 109:63-77

Single domain antibodies targeting pathological tau protein: Influence of four IgG subclasses on efficacy and toxicity

Congdon, Erin E; Pan, Ruimin; Jiang, Yixiang; Sandusky-Beltran, Leslie A; Dodge, Andie; Lin, Yan; Liu, Mengyu; Kuo, Min-Hao; Kong, Xiang-Peng; Sigurdsson, Einar M

EBioMedicine. 2022 Sep 10; 84:104249

Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly

Congdon, Erin E; Jiang, Yixiang; Sigurdsson, Einar M

Seminars in cell & developmental biology. 2022 Jun ; 126:125-137

Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in Sydney

Sexton, Claire E; Anstey, Kaarin J; Baldacci, Filippo; Barnum, C J; Barron, Anna M; Blennow, Kaj; Brodaty, Henry; Burnham, Samantha; Elahi, Fanny M; Götz, Jürgen; Jeon, Yun-Hee; Koronyo-Hamaoui, Maya; Landau, Susan M; Lautenschlager, Nicola T; Laws, Simon M; Lipnicki, Darren M; Lu, Hanzhang; Masters, Colin L; Moyle, Wendy; Nakamura, Akinori; Pasinetti, Giulio Maria; Rao, Naren; Rowe, Christopher; Sachdev, Perminder S; Schofield, Peter R; Sigurdsson, Einar M; Smith, Kate; Srikanth, Velandai; Szoeke, Cassandra; Tansey, Malú G; Whitmer, Rachel; Wilcock, Donna; Wong, Tien Y; Bain, Lisa J; Carrillo, Maria C

Alzheimer's & dementia. 2022 Jan ; 18:178-190

Current Status of Clinical Trials on Tau Immunotherapies

Ji, Changyi; Sigurdsson, Einar M

Drugs. 2021 Jul ; 81:1135-1152