Tsien Lab | NYU Langone Health

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Tsien Lab

We study how neuronal networks meet the demands of information processing in the brain.

The Tsien Lab at NYU Langone works in many areas of neuroscience, with multiple approaches, but there is a unifying question: How are neuronal networks attuned to meeting the demands of information processing in the brain?

We have seen our share of controversial issues over the years. Do neurotransmitters work exclusively by opening ligand-gated channels or do they modulate voltage-gated channels as well? Do calcium channels exist, are there multiple types, and if so, how many? Do ion channels switch between different patterns of opening and closing—gating modes—and is this switching central to how channels are modulated? Is activity-dependent control of neuronal gene expression more than a matter of raising calcium concentration in the nucleus? While these issues were once hotly debated, most neuroscientists would now regard them as settled long in the distant past.

In our current work, we do not seek controversy, but are willing to deal with it in order to test unconventional ideas. With past progress in mind, we’re tackling today’s unresolved questions with the guiding principle that new tool development is paramount to successfully pushing science forward.

Contact Us

Richard W. Tsien, PhD
Chair, Department of Neuroscience and Physiology
Director, Neuroscience Institute
The Druckenmiller Professor of Neuroscience, Department of Neuroscience and Physiology
Professor, Department of Neurology

Neuroscience Institute
435 East 30th Street
Science Building, 12th Floor, Room 1216
New York, NY 10016
Phone: 646-501-4520
Fax: 646-501-4529
Email: richard.tsien@nyulangone.org