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Wong Lab Publications

Learn more about research being performed in the Wong Lab by reading our latest publications.

Recent Publications

Acquired Cross-resistance in Small Cell Lung Cancer due to Extrachromosomal DNA Amplification of MYC paralogs

Pal Choudhuri, Shreoshi; Girard, Luc; Lim, Jun Yi Stanley; Wise, Jillian F; Freitas, Braeden; Yang, Di; Wong, Edmond; Hamilton, Seth; Chien, Victor D; Kim, Yoon Jung; Gilbreath, Collin; Zhong, Jun; Phat, Sarah; Myers, David T; Christensen, Camilla L; Mazloom-Farsibaf, Hanieh; Stanzione, Marcello; Wong, Kwok-Kin; Hung, Yin P; Farago, Anna F; Meador, Catherine B; Dyson, Nicholas J; Lawrence, Michael S; Wu, Sihan; Drapkin, Benjamin J

Cancer discovery. 2024 May 01; 14:804-827

Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer

Pillai, Ray; LeBoeuf, Sarah E; Hao, Yuan; New, Connie; Blum, Jenna L E; Rashidfarrokhi, Ali; Huang, Shih Ming; Bahamon, Christian; Wu, Warren L; Karadal-Ferrena, Burcu; Herrera, Alberto; Ivanova, Ellie; Cross, Michael; Bossowski, Jozef P; Ding, Hongyu; Hayashi, Makiko; Rajalingam, Sahith; Karakousi, Triantafyllia; Sayin, Volkan I; Khanna, Kamal M; Wong, Kwok-Kin; Wild, Robert; Tsirigos, Aristotelis; Poirier, John T; Rudin, Charles M; Davidson, Shawn M; Koralov, Sergei B; Papagiannakopoulos, Thales

Science advances. 2024 Mar 29; 10:eadm9859

EML4-ALK fusions drive lung adeno-to-squamous transition through JAK-STAT activation

Qin, Zhen; Yue, Meiting; Tang, Shijie; Wu, Fengying; Sun, Honghua; Li, Yuan; Zhang, Yongchang; Izumi, Hiroki; Huang, Hsinyi; Wang, Wanying; Xue, Yun; Tong, Xinyuan; Mori, Shunta; Taki, Tetsuro; Goto, Koichi; Jin, Yujuan; Li, Fei; Li, Fu-Ming; Gao, Yijun; Fang, Zhaoyuan; Fang, Yisheng; Hu, Liang; Yan, Xiumin; Xu, Guoliang; Chen, Haiquan; Kobayashi, Susumu S; Ventura, Andrea; Wong, Kwok-Kin; Zhu, Xueliang; Chen, Liang; Ren, Shengxiang; Chen, Luo-Nan; Ji, Hongbin

Journal of experimental medicine. 2024 Mar 04; 221:

EZH2 inhibition promotes tumor immunogenicity in lung squamous cell carcinomas

DuCote, Tanner J; Song, Xiulong; Naughton, Kassandra J; Chen, Fan; Plaugher, Daniel R; Childress, Avery R; Gellert, Abigail R; Skaggs, Erika M; Qu, Xufeng; Liu, Jinze; Liu, Jinpeng; Li, Fei; Wong, Kwok-Kin; Brainson, Christine F

Cancer research communications. 2024 Feb 13; 4:388-403

A Phase 1/2 multicenter trial of DKN-01 as monotherapy or in combination with docetaxel for the treatment of metastatic castration-resistant prostate cancer (mCRPC)

Wise, David R; Pachynski, Russell K; Denmeade, Samuel R; Aggarwal, Rahul R; Deng, Jiehui; Febles, Victor Adorno; Balar, Arjun V; Economides, Minas P; Loomis, Cynthia; Selvaraj, Shanmugapriya; Haas, Michael; Kagey, Michael H; Newman, Walter; Baum, Jason; Troxel, Andrea B; Griglun, Sarah; Leis, Dayna; Yang, Nina; Aranchiy, Viktoriya; Machado, Sabrina; Waalkes, Erika; Gargano, Gabrielle; Soamchand, Nadia; Puranik, Amrutesh; Chattopadhyay, Pratip; Fedal, Ezeddin; Deng, Fang-Ming; Ren, Qinghu; Chiriboga, Luis; Melamed, Jonathan; Sirard, Cynthia A; Wong, Kwok-Kin

Prostate cancer & prostatic diseases. 2024 Feb 10;

FGFR inhibition augments anti-PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression

Okato, Atsushi; Utsumi, Takanobu; Ranieri, Michela; Zheng, Xingnan; Zhou, Mi; Pereira, Luiza D; Chen, Ting; Kita, Yuki; Wu, Di; Hyun, Hyesun; Lee, Hyojin; Gdowski, Andrew S; Raupp, John D; Clark-Garvey, Sean; Manocha, Ujjawal; Chafitz, Alison; Sherman, Fiona; Stephens, Janaye; Rose, Tracy L; Milowsky, Matthew I; Wobker, Sara E; Serody, Jonathan S; Damrauer, Jeffrey S; Wong, Kwok-Kin; Kim, William Y

Journal of clinical investigation. 2024 Jan 16; 134:

Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy

Mukhopadhyay, Suman; Huang, Hsin-Yi; Lin, Ziyan; Ranieri, Michela; Li, Shuai; Sahu, Soumyadip; Liu, Yingzhuo; Ban, Yi; Guidry, Kayla; Hu, Hai; Lopez, Alfonso; Sherman, Fiona; Tan, Yi Jer; Lee, Yeuan Ting; Armstrong, Amanda P; Dolgalev, Igor; Sahu, Priyanka; Zhang, Tinghu; Lu, Wenchao; Gray, Nathanael S; Christensen, James G; Tang, Tracy T; Velcheti, Vamsidhar; Khodadadi-Jamayran, Alireza; Wong, Kwok-Kin; Neel, Benjamin G

Cancer research. 2023 Dec 15; 83:4095-4111

Correction to: Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis

Jin, Yujuan; Zhao, Qiqi; Zhu, Weikang; Feng, Yan; Xiao, Tian; Zhang, Peng; Jiang, Liyan; Hou, Yingyong; Guo, Chenchen; Huang, Hsinyi; Chen, Yabin; Tong, Xinyuan; Cao, Jiayu; Li, Fei; Zhu, Xueliang; Qin, Jun; Gao, Dong; Liu, Xin-Yuan; Zhang, Hua; Chen, Luonan; Thomas, Roman K; Wong, Kwok-Kin; Zhang, Lei; Wang, Yong; Hu, Liang; Ji, Hongbin

National science review. 2023 Dec ; 10:nwac224