Walker Laboratory
Dr. Peter Walker's lab at NYU Langone studies early interventions for osteoarthritis and unicompartmental and total knee replacement.
Cronstein Lab | NYU Langone Health
The Cronstein Lab at NYU Langone focuses on the anti-inflammatory effects of adenosine and its role in wound healing and bone metabolism.
Multinuclear MRI to Assess Joint Homeostasis After Knee Injury
The purpose of this research study is to study joint health after an anterior cruciate ligament (ACL) injury both in the short and long term. We will look at how the body responds to injury by gathering images of participants' knees with magnetic resonance imaging (MRI).
Multiparametric Mapping of Knee Joint with Magnetic Resonance Fingerprinting
The purpose of this study is to develop a non-invasive way (non-invasive meaning that no medical instruments will breach your skin) of taking pictures using a magnetic resonance imaging (MRI) that can help identify the early stages of osteoarthritis (OA) in the knees and predict OA progression. MRI is a technique for making detailed pictures of structures in the body without radiation.
Rapid Quantitative Assessment of Knee Joint with Compressed Sensing
The purpose of this study is to develop a non-invasive way (non-invasive meaning that no medical instruments will breach your skin) of taking pictures using a Magnetic Resonance Imaging (MRI) that can help identify the early stages of osteoarthritis (OA) in the knees and predict OA progression. MRI is a technique for making detailed pictures of structures in the body without radiation. If you have knee OA, your participation will involve 3 visits that are detailed below. If you are a healthy control subject, your participation will involve 1 visit that is detailed below.
A Phase 3 Prospective Multicenter Double-Blind Randomized Placebo Controlled Study to Evaluate the Efficacy of Amniotic Suspension Allograft (ASA) in Patients with Osteoarthritis of the Knee
The purpose of this clinical research study is to learn more about the use of the study drug, amnion suspension allograft (written as ‘ASA’ in this form), for the treatment of osteoarthritis (OA) of the knee. The ASA injection is being studied to see if it improves the knee pain and function in people with knee OA.
Data-Driven Learning Framework for Fast Quantitative Knee Joint Mapping
The purpose of this research study is to develop and improve current 3D MRI sequences in the assessment of the human knee joint in patients with early osteoarthritis and in healthy controls. This study will utilize 3D MRI and data-driven learning-based compressed sensing (DDL-CS), to analyze the knee joint and provide a better understanding of cartilage (a type of connective tissue) and menisci (crescent-shaped bands of thick, rubbery cartilage that is attached to your shin bone) of the knee joint.
Duration of Time After Knee Intra-articular Injection to Pain Relief
The purpose of this study is to determine the timeline and level of improvement experienced by patients after receiving intra-articular injections in the knee. You are being asked to take part in this research study because you have osteoarthritis of the knee and you are scheduled to undergo intraarticular injection of corticosteroids, hyaluronic acid, or platelet rich plasma (PRP).
Feasibility and Safety of Geniculate Artery Embolization for Treatment of Mild to Moderate Knee Osteoarthritis
The purpose of this study is to evaluate the safety and feasibility of genicular artery embolization using EmbozeneTM microspheres for mild-to-moderate knee osteoarthritis (OA) detected on knee x-ray in patients with knee pain resistant to conservative treatment. Embolization is a minimally invasive surgical technique. The purpose of embolization is to prevent blood flow to an area of the body. Embolization of the geniculate artery will be performed using Embozene™ Microspheres. Embozene™ microspheres are embolization material that are approved by the Food and Drug Administration (FDA) for other indications including arteriovenous malformations (AVM) or tangled blood vessels, certain types of tumors, and embolization of arteries in the prostate for treatment of symptomatic benign prostatic hyperplasia (BPH). In this study, Embozene™ microspheres are considered investigational because they are not FDA-approved for embolization of the geniculate artery for the treatment of knee pain in patients with knee osteoarthritis.
SWIFT TRIAL: SURGICAL WEIGHT-LOSS TO IMPROVE FUNCTIONAL STATUS TRAJECTORIES FOLLOWING TOTAL KNEE ARTHROPLASTY
In many patients, obesity is associated with arthritis in the knee that causes pain and difficulty moving or walking, which may get worse over time as the arthritis progresses. Many patients choose TKA to reduce the knee pain and improve mobility and quality of life. However, TKA surgery in patients with obesity may have a higher risk of complications than TKA surgery in patients without obesity. Because of these concerns, patients with obesity are encouraged by many orthopedic centers to lose weight prior to undergoing TKA surgery. Several recent studies suggest that having weight loss surgery before TKA surgery may lower the risk of the TKA surgery and improve long-term outcomes in patients with obesity. The purpose of this study is to determine whether weight-loss surgery prior to TKA surgery reduces risk and improves long-term outcomes.
