Prospective Multicenter Single-Arm Study of VanquishTM Water Vapor Ablation for Prostate Cancer
This study will look at how well the Vanquish Water Vapor Ablation Device works to treat people with Gleason Grade Group 2 (GGG2) localized intermediate-risk prostate cancer. People who are in the study will get the Vanquish System treatment. The doctors will levaluate the results of people who received the treatment for 12 months and then decide if the treatment is safe and how effective it works. The doctors will also look at the results from 36 months of follow-up. This will help investigators learn more about the treatment and how well it works. The doctors will follow the people in the study for 60 months. If participants have cancer that remains in their body, they may be able to receive more treatment.
Prospective NIPT Sample Collection Protocol
The purpose of this study is to collect blood samples from volunteers to develop a new noninvasive prenatal test, that can detect these genetic abnormalities in blood samples. The intended clinical benefit of the new test is to provide physicians and laboratories with a test that provides an opportunity for early detection of these genetic abnormalities without harming the fetus or the pregnant mother. This test is still being developed and validated and is not Food and Drug Administration (FDA) approved for clinical use.
Prospective Pilot Study on Geniculate Artery Embolization for Treatment of Persistent Knee Pain Post Total Knee Arthroplasty
The goal of this proposed prospective, single-center, single-arm trial is to evaluate the safety and efficacy of Geniculate Artery Embolization (GAE) for treatment of persistent postsurgical knee pain following total knee arthroplasty (TKA). Knee replacement surgery (total knee arthroplasty-TKA) is an effective intervention for the treatment of chronic knee pain and disability in patients with knee osteoarthritis (OA). However, approximately 10% to 34% of patients experience persistent chronic pain after TKA. Persistent postsurgical pain is defined as persistent pain of at least three to six months duration that develops or increases in intensity after surgery and affects health-related quality of life. While the etiology of persistent pain following TKA is multifactorial, there is growing evidence that inflammation (synovitis) and patient-specific inflammatory response to surgery may influence the long-term clinical outcome following knee replacement. Over the past decade, embolization of the genicular arteries (genicular artery embolization- GAE) has been evaluated for the treatment of knee OA, showing significant improvement in knee pain, function, and quality of life.
Prospective Randomized Placebo-Controlled Trial of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE)
You can participate in this study if you are newly diagnosed with brain cancer (glioblastoma). The purpose of this study is to evaluate a peptide vaccine (SurVaxM) in emulsion with Montanide given together with locally administered sargramostim plus adjuvant oral temozolomide (TMZ) (Arm A) versus saline-Montanide emulsion with locally administered saline (instead of sargramostim) plus adjuvant oral temozolomide (TMZ) (Arm B). Patients will be randomized 3:2 = A:B to treatment with SurVaxM in emulsion with Montanide plus sargramostim (local injection) and standard-of-care TMZ (Arm A), or placebo (saline in emulsion with Montanide) plus saline (local injection) and standard-of-care TMZ (Arm B). To be eligible to participate, patients must have undergone a contrast enhanced, post-operative MRI scan within 72 hours of surgical resection. All patients must undergo randomization within 16 weeks of surgical tumor resection in order to participate.
Prostate Artery Embolization for Male Urinary Dysfunction | NYU Langone Health
NYU Langone doctors treat some types of urinary problems with nonsurgical embolization to improve bladder function.
Prostate Cancer | NYU Langone Health
Doctors at NYU Langone’s Perlmutter Cancer Center are experts in the most advanced techniques for prostate cancer diagnosis.
Prostate Cancer Diagnosis | NYU Langone Health
Doctors at NYU Langone’s Perlmutter Cancer Center are experts in the most advanced techniques for diagnosing prostate cancer.
Prostate Cancer Recovery & Support | NYU Langone Health
Doctors at NYU Langone’s Perlmutter Cancer Center provide support for men and their families during and after treatment for prostate cancer.
Prostate Cancer Screening | NYU Langone Health
Doctors at NYU Langone’s Perlmutter Cancer Center help men understand the benefits and risks of prostate cancer screening.
PRostate Cancer Treatment with the AQUABEAM Robotic System
This study is testing a special machine called the AQUABEAM Robotic System. This machine is designed to treat cancer tissue in the prostate. It does this by using a strong waterjet to remove the cancer tissue in a way that's less invasive than surgery. The machine is used with the help of ultrasound images and a tiny camera to make sure it is running properly. Before the treatment, the doctor plans where to use the machine. During the treatment, a device is inserted into the urethra (a tube in the body), and it sprays the waterjet to remove the prostate tissue as planned by the doctor. This study is being done at different hospitals, and it's trying to find out if this machine is safe for treating prostate cancer. The study team expects to enroll patients over six months, and each patient will be followed for a year after the treatment. The whole study, from the first patient joining to the last check-up, will take around 18 months. The study team is doing this to make sure the machine works well and effectively helps treat patients with prostate cancer.