Role of the Decision-Making Reference Point in Cognition and Psychopathology
Mood disorders are characterized by a tendency to subjectively evaluate objectively positive outcomes in a negative light. A fundamental feature of nearly all standard models of decision-making is the idea that the subjective value of any choice option is shaped by a psychological and neurobiological variable called the reference point. The reference point serves as an internal benchmark against which values of all possible future events are weighed. Whether any given activity is viewed as an improvement or decrement in the quality of life is determined by whether that activity yields an outcome evaluated as better or worse than the reference point. Using behavioral decision-making tasks informed by an understanding of how human expectations are set, here propose to test the hypothesis that affective mood impacts the decision-making reference point—the computational instantiation of our expectations—and thus drives shifts in subjective value that mark mood pathologies like major depressive disorder (MDD). Our core hypothesis is that the affective changes associated with MDD can be largely captured as a pathological over-setting of the neurobiological reference point, such that nearly all activities appear as undesirable outcomes that lie well below the pathologically high reference point mark.
Role of the oral cavity in inflammatory bowel disease
The purpose of this investigation is to create a study bank of clinical data, peripheral blood, oral and gut microbiomes, and mucosal pinch biopsy specimens obtained during clinically indicated oral examinations or endoscopies in subjects with and without inflammatory bowel disease. This study bank will allow us to examine relationships between the oral cavity and IBD.
Ronald O. Perelman Center for Emergency Services | NYU Langone Health
NYU Langone’s Ronald O. Perelman Center for Emergency Services offers emergency care for illness and injuries.
Rosacea | NYU Langone Health
NYU Langone doctors offer many treatment options for rosacea, a chronic skin condition that causes facial redness, inflammation, and blemishes.
Rotator cuff sparing total shoulder arthroplasty - A prospective randomized clinical trial
The purpose of this study is to collect and evaluate long-term clinical data on patients whose total shoulder replacement (TSR) is performed using the traditional surgical approach (called the subscapularis release approach) as compared to patients who have a TSR procedure done using a newer surgical approach (called the rotator cuff sparing approach). Our study proposes to enroll two groups of patients with shoulder arthritis. The first group will be treated with the traditional TSR procedure. The second group will be treated with this new rotator cuff sparing surgical technique for TSR where the rotator cuff is never violated. After surgery, we will examine motion, strength, and functional use of the shoulder. In addition, we will specifically test the rotator cuff strength after the surgery. In this fashion, we plan to test the hypothesis that rotator cuff sparing TSR can improve the rotator cuff function while maintaining the excellent pain relief and motion that is normally observed after the traditional TSR procedure. For patients with arthritis, TSR can successfully improve pain and restore function. As a result, TSR has become the treatment of choice for patients with shoulder arthritis. Despite these generally good outcomes, however, there are concerns that rotator cuff function is suboptimal after surgery. One of the rotator cuff tendons is usually cut during the TSR procedure to insert the prosthesis and then repaired at the end of the surgery. If the tendon does not heal adequately, patients may experience persistent weakness, pain, and even failure of the replacement. Recently, a surgical technique called rotator cuff sparing TSR has been described where the procedure can be performed without ever cutting any of the rotator cuff tendons. As such, there should be minimized risk to the rotator cuff function after the surgery.
Running Performance Programs | NYU Langone Health
NYU Langone’s Sports Performance Center provides customized evaluations to help you become a better runner.
Rusk Rehabilitation | NYU Langone Health
At NYU Langone’s Rusk Rehabilitation, you receive care that meets your physical, social, emotional, cognitive, and psychological needs.
Rusk Rehabilitation at Joan H. & Preston Robert Tisch Center at Essex Crossing | NYU Langone Health
At Rusk Rehabilitation at Joan H. & Preston Robert Tisch Center at Essex Crossing, our team provides physical therapy.
Rusk Rehabilitation at Joan H. & Preston Robert Tisch Center at Essex Crossing Doctors | NYU Langone Health
Find a doctor at the Rusk Rehabilitation at Joan H. & Preston Robert Tisch Center at Essex Crossing at NYU Langone.
Rusk Rehabilitation at NYU Langone Advanced Orthopedic Associates—Long Island, East Patchogue | NYU Langone Health
At Rusk Rehabilitation at NYU Langone Advanced Orthopedic Associates—Long Island, East Patchogue, our team provides physical therapy.