SELECT-SLE: A Phase 3 Program to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Moderately to Severely Active SLE
The purpose of this program is to assess the safety and efficacy of upadacitinib compared with placebo (fake drug) for the treatment of signs and symptoms in adults with moderately to severely active systemic lupus erythematosus (SLE). Upadacitinib is an experimental drug that blocks the actions of proteins known as Janus kinases (Jaks). Jaks are involved in the immune response and cell growth including blood cells. The study drug has been approved by regulatory authorities to treat other medical conditions such as rheumatoid arthritis, psoriatic arthritis, and axial spondylarthritis but is not approved to treat lupus. Therefore, the use of the study drug is investigational (experimental) for the purposes of this program.
Selective Mutism Service | NYU Langone Health
The Selective Mutism Service is located at the Child Study Center, part of Hassenfeld Children’s Hospital at NYU Langone.
Seligman Center for Advanced Therapeutics | NYU Langone Health
NYU Langone’s Seligman Center for Advanced Therapeutics connects patients who have rheumatic conditions with clinical trials.
Seligman Center for Advanced Therapeutics Doctors | NYU Langone Health
Find a doctor at the Seligman Center for Advanced Therapeutics at NYU Langone.
SendSafe Email | NYU Langone Health
We have a secure email system, SendSafe, for external (outside of NYU Langone Health) email communications.
Sepsis in Children | NYU Langone Health
Experts at Hassenfeld Children’s Hospital at NYU Langone look for early warning signs of sepsis, a serious inflammatory condition.
Septal Myectomy Surgery for Hypertrophic Cardiomyopathy | NYU Langone Health
NYU Langone cardiac surgeons may perform septal myectomy surgery to manage a severe form of hypertrophic cardiomyopathy (HCM).
Serologic Testing and Genomic Analysis of Autoimmune Immune-Mediated and Rheumatic Patients with COVID-19 (SAGA)
This is a prospective cohort study involving all subjects enrolled in the Web-based Assessment of Autoimmune, Immune-Mediated, and Rheumatic Patients during the COVID-19 Pandemic (WARCOV) study (study number: i20-00389). Subjects with immune-mediated inflammatory disorders (IMID) previously enrolled in WARCOV will be asked to provide blood samples for SARS-CoV-2 antibody testing, blood typing, genomic analysis, inflammatory cytokine measurements, and biobanking purposes and nasal swabs for detection of SARS-CoV 2 receptor such as ACE2 and TMPRSS2. An optional directed musculoskeletal examination will also be performed by a study physician. Clinico-epidemiologic information will be obtained from the WARCOV database.
Services at NYU Langone Ambulatory Care Rego Park | NYU Langone Health
Doctors at NYU Langone Ambulatory Care Rego Park specialize in cardiology, gynecology, urology, sports medicine, and diagnostic imaging.
Services at NYU Langone at Great Neck Medical | NYU Langone Health
NYU Langone at Great Neck Medical offers internal medicine, as well as a variety of medical specialties, all in one convenient location.