Inflammatory Bowel Disease Research Program
The Inflammatory Bowel Disease Research Program at NYU Langone Health bridges basic, clinical, and educational disciplines and brings together faculty who build on the breadth of our immunology, microbiology, and cell biology research to foster cross-disciplinary collaborations and studies. Our mission is to build on our institution’s tradition of turning basic science discoveries into treatments for inflammatory bowel diseases (IBD) including Crohn’s disease and ulcerative colitis.
Following their research on immune signaling molecules, NYU Langone microbiologists worked with pharmaceutical companies to develop the drug infliximab, which blocks one such molecule called TNF-α. It remains among the most commonly used therapies for IBD.
Faculty at the Inflammatory Bowel Disease Research Program work hand-in-hand with gastroenterologists and surgeons at NYU Langone’s clinical Inflammatory Bowel Disease Center with the goal of discovering new treatment strategies and how best to apply them to improve patient care.
Our Leadership
Jordan E. Axelrad, MD, MPH, is our program director. Dr. Axelrad is recognized for his research on malignant and infectious complications of IBD, specifically, in elucidating how exposures such as gastrointestinal infections may complicate IBD or trigger it to develop.
David P. Hudesman, MD, is the director of our Inflammatory Bowel Disease Center. Together with Dr. Axelrad, they manage IBD research studies and clinical trials representing partnerships among clinicians, scientists, and industry.
Available Positions
We are hiring research scientists to join our team. Learn more about our available positions.
Select Faculty Publications
Preexisting Skin-Resident CD8 and γδ T-cell Circuits Mediate Immune Response in Merkel Cell Carcinoma and Predict Immunotherapy Efficacy
Cancer discovery. 2024 Sep 04; 14:1631-1652
Decline in use of high-risk agents for tight glucose control among older adults with diabetes in New York City: 2017-2022
Journal of the American Geriatrics Society. 2024 Sep ; 72:2721-2729
Sarcopenia Is a Risk Factor for Postoperative Complications Among Older Adults With Inflammatory Bowel Disease
Inflammatory bowel diseases. 2024 Aug 23;
Severe Polypharmacy Increases Risk of Hospitalization Among Older Adults with IBD
American journal of gastroenterology. 2024 Aug 20;
A Platelet Reactivity ExpreSsion Score derived from patients with peripheral artery disease predicts cardiovascular risk
Nature communications. 2024 Aug 20; 15:6902
Cardiometabolic Comorbidity Burden and Circulating Biomarkers in Patients with Chronic Coronary Disease in the ISCHEMIA Trials
American journal of cardiology. 2024 Aug 15; 225:118-124
Clinical validation of digital assessment tools and machine learning models for remote measurement of psoriasis and psoriatic arthritis: a proof-of-concept study
Journal of rheumatology. 2024 Aug 01; 51:781-789
The Burden of Work Productivity and Activity Impairment in Patients with Psoriasis, Psoriatic Arthritis, Ulcerative Colitis, and Crohn's Disease
Digestive diseases & sciences. 2024 Aug ; 69:2784-2795