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Boeke Lab Boeke Lab Publications

Boeke Lab Publications

Below are select publications that highlight the work done in the Boeke Lab.

Selected Publications

De novo assembly and delivery to mouse cells of a 101 kb functional human gene

Mitchell, Leslie A; McCulloch, Laura H; Pinglay, Sudarshan; Berger, Henri; Bosco, Nazario; Brosh, Ran; Bulajić, Milica; Huang, Emily; Hogan, Megan S; Martin, James A; Mazzoni, Esteban O; Davoli, Teresa; Maurano, Matthew T; Boeke, Jef D

Genetics. 2021 Mar 20;

A versatile platform for locus-scale genome rewriting and verification

Brosh, Ran; Laurent, Jon M; Ordoñez, Raquel; Huang, Emily; Hogan, Megan S; Hitchcock, Angela M; Mitchell, Leslie A; Pinglay, Sudarshan; Cadley, John A; Luther, Raven D; Truong, David M; Boeke, Jef D; Maurano, Matthew T

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2021 Mar 09; 118:

Application of counter-selectable marker PIGA in engineering designer deletion cell lines and characterization of CRISPR deletion efficiency

Li, Donghui; Sun, Xiaoji; Yu, Fangzhou; Perle, Mary Ann; Araten, David; Boeke, Jef D

Nucleic acids research. 2021 Mar 18; 49:2642-2654

Genetic interaction mapping informs integrative structure determination of protein complexes

Braberg, Hannes; Echeverria, Ignacia; Bohn, Stefan; Cimermancic, Peter; Shiver, Anthony; Alexander, Richard; Xu, Jiewei; Shales, Michael; Dronamraju, Raghuvar; Jiang, Shuangying; Dwivedi, Gajendradhar; Bogdanoff, Derek; Chaung, Kaitlin K; Hüttenhain, Ruth; Wang, Shuyi; Mavor, David; Pellarin, Riccardo; Schneidman, Dina; Bader, Joel S; Fraser, James S; Morris, John; Haber, James E; Strahl, Brian D; Gross, Carol A; Dai, Junbiao; Boeke, Jef D; Sali, Andrej; Krogan, Nevan J

Science. 2020 12 11; 370:

Pathway engineering in yeast for synthesizing the complex polyketide bikaverin

Zhao, Meng; Zhao, Yu; Yao, Mingdong; Iqbal, Hala; Hu, Qi; Liu, Hong; Qiao, Bin; Li, Chun; Skovbjerg, Christine A S; Nielsen, Jens Christian; Nielsen, Jens; Frandsen, Rasmus J N; Yuan, Yingjin; Boeke, Jef D

Nature communications. 2020 12 03; 11:6197

BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells

Mita, Paolo; Sun, Xiaoji; Fenyö, David; Kahler, David J; Li, Donghui; Agmon, Neta; Wudzinska, Aleksandra; Keegan, Sarah; Bader, Joel S; Yun, Chi; Boeke, Jef D

Nature structural & molecular biology. 2020 Feb ; 27:179-191

Superloser: A Plasmid Shuffling Vector for Saccharomyces cerevisiae with Exceedingly Low Background

Haase, Max A B; Truong, David M; Boeke, Jef D

G3 : genes - genomes - genetics. 2019 Aug 08; 9:2699-2707

Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast

Luo, Jingchuan; Sun, Xiaoji; Cormack, Brendan P; Boeke, Jef D

Nature. 2018 08 ; 560:392-396