Charvet Lab | NYU Langone Health

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Charvet Lab

Advancing technology to provide accessible symptom management to those living with MS and other neurological conditions

We are studying ways to measure how the so-called “silent” symptoms of MS can be better detected and treated.

Measurement

New and advanced measures of cognitive performance can help us understand how even subtle cognitive changes can influence quality of life. These measures can be linked to disease markers using advanced neuroimaging and real world functioning on a daily basis.

Management

We are studying new treatments such as computerized cognitive training, transcranial direct current stimulation (tDCS), and Virtual Reality (VR).

Transcranial Direct Current Stimulation (tDCS)

tDCS is a noninvasive brain stimulation technique. Using a small handheld device, low levels of electrical current are passed through scalp electrodes to target specific brain regions. tDCS is very safe and well-tolerated, and can be paired with a training activity such as cognitive or motor exercises. We are studying ways that this treatment can be most effectively used to help those living with MS and other neurological disorders.

Woman wearing transcranial direct current stimulation headset
The tDCS device delivers current that is passed through electrodes placed on the scalp.  We use a headset to hold the electrodes (enclosed in sponges) in position.

Treatment delivered at home with telemedicine: RS-tDCS

A unique feature of our tDCS program is that we provide remotely supervised or RS-tDCS to deliver treatment to our participants in their homes. We provide all equipment and training, and connect live with participants during their sessions.

Current study opportunities with RS-tDCS

We are currently recruiting MS participants for clinical trials to treat fatigue and upper extremity motor functioning using tDCS paired with cognitive and motor rehabilitation, respectively.  Additionally, we are completing an imaging study with tDCS where a research MRI is completed before and after a series of RS-tDCS treatment sessions targeting fatigue.

Virtual Reality (VR)

Virtual reality (VR) is a computer-based application that places users into a simulated three-dimensional environment. The engaging qualities of VR, which can include high-resolution images, surround sound audio, binocular overlap, haptic feedback, and tracking headset perspective, can construct realistic virtual environments for patients. Through headset movement or use of hand controllers, sensors, and trackers, VR results in an experience of sensory immersion with the option for interaction in real-time.

VR can be used as a treatment for individuals with neurological disorders by distracting from acute symptoms, such as pain or fatigue, as well as training individuals to use therapeutic self-management strategies.

Woman wearing virtual reality headset uses handheld controllers
 VR is experienced through a headset, with handheld controllers used to navigate the virtual environment.

Contact Us

If you are interested in learning more about any of our studies, please complete this form. (Please note that Internet Explorer users should consider disabling their ad blocker or using a different browser to properly access the form.)

If you would like to reach us directly:
Email: charvetlab@nyulangone.org
Phone: 646-501-7511