Cryo–Electron Microscopy Laboratory Featured Publications

Our staff members and collaborators frequently publish their research in leading peer-reviewed publications. Here is a selection of their recent accomplishments.

Selected Publications

BRAF oncogenic mutants evade autoinhibition through a common mechanism

Lavoie, Hugo; Jin, Ting; Lajoie, Driss; Decossas, Marion; Gendron, Patrick; Wang, Bing; Filandr, Frantisek; Sahmi, Malha; Hwa Jo, Chang; Weber, Sandra; Arseneault, Geneviève; Tripathy, Sasmita; Beaulieu, Pierre; Schuetz, Doris A; Schriemer, David C; Marinier, Anne; Rice, William J; Maisonneuve, Pierre; Therrien, Marc

Science (New York, N.Y.). 2025 May 29; 388:eadp2742

Substrate translocation and inhibition in human dicarboxylate transporter NaDC3

Li, Yan; Song, Jinmei; Mikusevic, Vedrana; Marden, Jennifer J; Becerril, Alissa; Kuang, Huihui; Wang, Bing; Rice, William J; Mindell, Joseph A; Wang, Da-Neng

Nature structural & molecular biology. 2025 Mar ; 32:502-512

Structural insights into the diversity and DNA cleavage mechanism of Fanzor

Xu, Peiyu; Saito, Makoto; Faure, Guilhem; Maguire, Samantha; Chau-Duy-Tam Vo, Samuel; Wilkinson, Max E; Kuang, Huihui; Wang, Bing; Rice, William J; Macrae, Rhiannon K; Zhang, Feng

Cell. 2024 Sep 19; 187:5238-5252.e20

Applying 3D ED/MicroED workflows toward the next frontiers

Aragon, Mahira; Bowman, Sarah E J; Chen, Chun Hsing; de la Cruz, M Jason; Decato, Daniel A; Eng, Edward T; Flatt, Kristen M; Gulati, Sahil; Li, Yuchen; Lomba, Charles J; Mercado, Brandon; Miller, Jessalyn; Palatinus, LukÃ¡Å¡; Rice, William J; Waterman, David; Zimanyi, Christina M

Acta crystallographica. Section C, Structural chemistry. 2024 Jun 01; 80:179-189

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1

Thomas, Jonathan F; Valencia-SÃ¡nchez, Marco Igor; Tamburri, Simone; Gloor, Susan L; Rustichelli, Samantha; GodÃnez-LÃ³pez, Victoria; De Ioannes, Pablo; Lee, Rachel; Abini-Agbomson, Stephen; Gretarsson, Kristjan; Burg, Jonathan M; Hickman, Allison R; Sun, Lu; Gopinath, Saarang; Taylor, Hailey F; Sun, Zu-Wen; Ezell, Ryan J; Vaidya, Anup; Meiners, Matthew J; Cheek, Marcus A; Rice, William J; Svetlov, Vladimir; Nudler, Evgeny; Lu, Chao; Keogh, Michael-Christopher; Pasini, Diego; Armache, Karim-Jean

Science advances. 2023 Aug 09; 9:eadg9832

Measuring the Effect of Ice Thickness and Microscope Configuration on Resolution in Single Particle Cryo-EM

Chua, Eugene Y D; Neselu, Kasahun; Wang, Bing; Rice, William J; Potter, Clinton S; Carragher, Bridget

Microscopy & microanalysis. 2023 Jul 22; 29:1040

CD19 CAR antigen engagement mechanisms and affinity tuning

He, Changhao; Mansilla-Soto, Jorge; Khanra, Nandish; Hamieh, Mohamad; Bustos, Victor; Paquette, Alice J; Garcia Angus, Andreina; Shore, Derek M; Rice, William J; Khelashvili, George; Sadelain, Michel; Meyerson, Joel R

Science immunology. 2023 Mar 10; 8:eadf1426

Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1

Thomas, Jonathan F; Valencia-Sánchez, Marco Igor; Tamburri, Simone; Gloor, Susan L; Rustichelli, Samantha; Godínez-López, Victoria; De Ioannes, Pablo; Lee, Rachel; Abini-Agbomson, Stephen; Gretarsson, Kristjan; Burg, Jonathan M; Hickman, Allison R; Sun, Lu; Gopinath, Saarang; Taylor, Hailey; Meiners, Matthew J; Cheek, Marcus A; Rice, William; Nudler, Evgeny; Lu, Chao; Keogh, Michael-Christopher; Pasini, Diego; Armache, Karim-Jean

bioRxiv : the preprint server for biology. 2023 Feb 23;

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Cryo–Electron Microscopy Laboratory Featured Publications | NYU Langone Health