Rodent Genetic Engineering Laboratory Featured Publications

Our staff members and collaborators frequently publish their research in leading peer-reviewed publications. Here is a selection of their recent accomplishments.

Selected Publications

Genome writing to dissect consequences of SVA retrotransposon disease X-Linked Dystonia Parkinsonism

Zhang, Weimin; Zhao, Yu; Prakash, Priya; Appleby, Heather L; Barriball, Kelly; Capponi, Simona; Jiang, Qingwen; Wudzinska, Aleksandra M; Vaine, Christine A; Ellis, Gwen; Rahman, Neha; Markovic, Stefan; Mishkit, Orin; Limberg, Kerry C; Maurano, Matthew T; Wadghiri, Youssef Z; Kim, Sang Yong; Timmers, H T Marc; Bragg, D Cristopher; Liddelow, Shane A; Brosh, Ran; Boeke, Jef D

bioRxiv : the preprint server for biology. 2025 Oct 08;

Oxytocin induces embryonic diapause

Minder, Jessica L; Winokur, Sarah B; Stephens, Janaye; Tong, Jie; Cassel, Naomi L; Schuster, Luisa; Issa, Habon A; Cammer, Michael; Khatri, Latika; Moisan, Gaia; Alvarado-Torres, Maria; Aristizábal, Orlando; Wadghiri, Youssef Z; Kim, Sang Yong; Valtcheva, Silvana; Lu, Catherine Pei-Ju; Chao, Moses V; Froemke, Robert C

Science advances. 2025 Mar 07; 11:eadt1763

Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries

Ortabozkoyun, Havva; Huang, Pin-Yao; Gonzalez-Buendia, Edgar; Cho, Hyein; Kim, Sang Y; Tsirigos, Aristotelis; Mazzoni, Esteban O; Reinberg, Danny

Molecular cell. 2024 Sep 19; 84:3406-3422.e6

T4 DNA polymerase prevents deleterious on-target DNA damage and enhances precise CRISPR editing

Yang, Qiaoyan; Abebe, Jonathan S; Mai, Michelle; Rudy, Gabriella; Kim, Sang Y; Devinsky, Orrin; Long, Chengzu

EMBO journal. 2024 Sep ; 43:3733-3751

On the genetic basis of tail-loss evolution in humans and apes

Xia, Bo; Zhang, Weimin; Zhao, Guisheng; Zhang, Xinru; Bai, Jiangshan; Brosh, Ran; Wudzinska, Aleksandra; Huang, Emily; Ashe, Hannah; Ellis, Gwen; Pour, Maayan; Zhao, Yu; Coelho, Camila; Zhu, Yinan; Miller, Alexander; Dasen, Jeremy S; Maurano, Matthew T; Kim, Sang Y; Boeke, Jef D; Yanai, Itai

Nature. 2024 Feb ; 626:1042-1048

Mouse genome rewriting and tailoring of three important disease loci

Zhang, Weimin; Golynker, Ilona; Brosh, Ran; Fajardo, Alvaro; Zhu, Yinan; Wudzinska, Aleksandra M; OrdoÃ±ez, Raquel; Ribeiro-Dos-Santos, AndrÃ© M; Carrau, Lucia; Damani-Yokota, Payal; Yeung, Stephen T; Khairallah, Camille; Vela Gartner, Antonio; Chalhoub, Noor; Huang, Emily; Ashe, Hannah J; Khanna, Kamal M; Maurano, Matthew T; Kim, Sang Yong; tenOever, Benjamin R; Boeke, Jef D

Nature. 2023 Nov ; 623:423-431

A conditional counterselectable Piga knockout in mouse embryonic stem cells for advanced genome writing applications

Zhang, Weimin; Brosh, Ran; McCulloch, Laura H; Zhu, Yinan; Ashe, Hannah; Ellis, Gwen; Camellato, Brendan R; Kim, Sang Yong; Maurano, Matthew T; Boeke, Jef D

iScience. 2022 Jun 17; 25:104438

Germline Transmission of a Circular Human Artificial Chromosome in the Mouse

Wudzinska, Aleksandra; Mitchell, Leslie A.; Brosh, Ran; Bosco, Nazario; Boccalatte, Francesco; Aifantis, Ioannis; Kim, Sang Y.; Davoli, Teresa; Boeke, Jef D.

bioRxiv.org : the preprint server for biology. 2022; 1-17

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Rodent Genetic Engineering Laboratory Featured Publications | NYU Langone Health