Rodent Genetic Engineering Laboratory Featured Publications

Our staff members and collaborators frequently publish their research in leading peer-reviewed publications. Here is a selection of their recent accomplishments.

Selected Publications

Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries

Ortabozkoyun, Havva; Huang, Pin-Yao; Gonzalez-Buendia, Edgar; Cho, Hyein; Kim, Sang Y; Tsirigos, Aristotelis; Mazzoni, Esteban O; Reinberg, Danny

Molecular cell. 2024 Sep 19; 84:3406-3422.e6

T4 DNA polymerase prevents deleterious on-target DNA damage and enhances precise CRISPR editing

Yang, Qiaoyan; Abebe, Jonathan S; Mai, Michelle; Rudy, Gabriella; Kim, Sang Y; Devinsky, Orrin; Long, Chengzu

EMBO journal. 2024 Sep ; 43:3733-3751

On the genetic basis of tail-loss evolution in humans and apes

Xia, Bo; Zhang, Weimin; Zhao, Guisheng; Zhang, Xinru; Bai, Jiangshan; Brosh, Ran; Wudzinska, Aleksandra; Huang, Emily; Ashe, Hannah; Ellis, Gwen; Pour, Maayan; Zhao, Yu; Coelho, Camila; Zhu, Yinan; Miller, Alexander; Dasen, Jeremy S; Maurano, Matthew T; Kim, Sang Y; Boeke, Jef D; Yanai, Itai

Nature. 2024 Feb ; 626:1042-1048

Mouse genome rewriting and tailoring of three important disease loci

Zhang, Weimin; Golynker, Ilona; Brosh, Ran; Fajardo, Alvaro; Zhu, Yinan; Wudzinska, Aleksandra M; OrdoÃ±ez, Raquel; Ribeiro-Dos-Santos, AndrÃ© M; Carrau, Lucia; Damani-Yokota, Payal; Yeung, Stephen T; Khairallah, Camille; Vela Gartner, Antonio; Chalhoub, Noor; Huang, Emily; Ashe, Hannah J; Khanna, Kamal M; Maurano, Matthew T; Kim, Sang Yong; tenOever, Benjamin R; Boeke, Jef D

Nature. 2023 Nov ; 623:423-431

A conditional counterselectable Piga knockout in mouse embryonic stem cells for advanced genome writing applications

Zhang, Weimin; Brosh, Ran; McCulloch, Laura H; Zhu, Yinan; Ashe, Hannah; Ellis, Gwen; Camellato, Brendan R; Kim, Sang Yong; Maurano, Matthew T; Boeke, Jef D

iScience. 2022 Jun 17; 25:104438

Klf5 establishes bi-potential cell fate by dual regulation of ICM and TE specification genes

Kinisu, Martin; Choi, Yong Jin; Cattoglio, Claudia; Liu, Ke; Roux de Bezieux, Hector; Valbuena, Raeline; Pum, Nicole; Dudoit, Sandrine; Huang, Haiyan; Xuan, Zhenyu; Kim, Sang Yong; He, Lin

Cell reports. 2021 Nov 09; 37:109982

Analysis of urgent/emergent conversions from monitored anesthesia care to general anesthesia with airway instrumentation

Kim, Sang; Chang, Brian A; Rahman, Amreen; Lin, Hung-Mo; DeMaria, Samuel; Zerillo, Jeron; Wax, David B

BMC anesthesiology. 2021 Jun 29; 21:183

Genetic variation of staphylococcal LukAB toxin determines receptor tropism

Perelman, Sofya S; James, David B A; Boguslawski, Kristina M; Nelson, Chase W; Ilmain, Juliana K; Zwack, Erin E; Prescott, Rachel A; Mohamed, Adil; Tam, Kayan; Chan, Rita; Narechania, Apurva; Pawline, Miranda B; Vozhilla, Nikollaq; Moustafa, Ahmed M; Kim, Sang Y; Dittmann, Meike; Ekiert, Damian C; Bhabha, Gira; Shopsin, Bo; Planet, Paul J; Koralov, Sergei B; Torres, Victor J

Nature microbiology. 2021 Jun ; 6:731-745

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Rodent Genetic Engineering Laboratory Featured Publications | NYU Langone Health